Results 41 to 50 of about 551 (135)

Interaction of akirin and pannier during embryogenesis of Drosophila melanogaster

, 2022
Akirin, a highly conserved protein found in nearly all eukaryote species, is a transcriptional cofactor that has been known to play a critical role in the muscular development in Drosophila.
Wandji, Georgette-vanelle
core   +2 more sources

Subolesin vaccination inhibits blood feeding and reproduction of Haemaphysalis longicornis in rabbits

Parasites & Vectors, 2020
Background Ticks can transmit numerous tick-borne pathogens and cause a huge economic loss to the livestock industry. Tick vaccines can contribute to the prevention of tick-borne diseases by inhibiting tick infestation or reproduction.
Seung-Hun Lee, Jixu Li, Paul Franck Adjou Moumouni, Kiyoshi Okado, Weiqing Zheng, Mingming Liu, Shengwei Ji, Soochong Kim, Rika Umemiya-Shirafuji, Xuenan Xuan   +9 more
doaj   +1 more source

Tick subolesin is an ortholog of the akirins described in insects and vertebrates

Developmental & Comparative Immunology, 2009
The tick protective antigen, subolesin, is a regulatory protein involved in the control of multiple cellular pathways. Subolesin is evolutionary conserved in invertebrates and vertebrates with sequence homology to akirins, a recently renamed group of proteins that were proposed to function as transcription factors in Drosophila and mice.
Galindo, Ruth C., Doncel-Pérez, Ernesto, Zivkovic, Zorica, Naranjo, Victoria, Gortazar, Christian, Mangold, Atilio Jose, Martín-Hernando, María Paz, Kocan, Katherine M., Rodríguez de la Fuente, José Javier   +8 more
openaire   +4 more sources

miR‐181c‐5p Exacerbates Hypoxia/Reoxygenation‐Induced Cardiomyocyte Apoptosis via Targeting PTPN4

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Background. Activation of cell apoptosis is a major form of cell death during myocardial ischemia/reperfusion injury (I/RI). Therefore, examining ways to control cell apoptosis has important clinical significance for improving postischemic recovery.
Liang Ge, Yin Cai, Fan Ying, Hao Liu, Dengwen Zhang, Yanjing He, Lei Pang, Dan Yan, Aimin Xu, Haichun Ma, Zhengyuan Xia, Rodrigo Franco   +11 more
wiley   +1 more source

A Review of the Genetics and Pathogenesis of Syndactyly in Humans and Experimental Animals: A 3‐Step Pathway of Pathogenesis

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3‐step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the suppression of the Bone ...
Mohammad M. Al-Qattan, Przemko Tylzanowski   +1 more
wiley   +1 more source

Gene Expression Profiling in Behcet’s Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy

Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Behçet disease (BD) is a chronic inflammatory multisystem disease characterized by oral and genital ulcers, uveitis, and skin lesions. Disease etiopathogenesis is still unclear. We aim to elucidate some aspects of BD pathogenesis and to identify specific gene signatures in peripheral blood cells (PBCs) of patients with active disease using novel gene ...
Antonio Puccetti, Piera Filomena Fiore, Andrea Pelosi, Elisa Tinazzi, Giuseppe Patuzzo, Giuseppe Argentino, Francesca Moretta, Claudio Lunardi, Marzia Dolcino, Marcella Reale   +9 more
wiley   +1 more source

In Silico Characterization and Structural Modeling of Dermacentor andersoni p36 Immunosuppressive Protein

Advances in Bioinformatics, Volume 2018, Issue 1, 2018., 2018
Ticks cause approximately $17–19 billion economic losses to the livestock industry globally. Development of recombinant antitick vaccine is greatly hindered by insufficient knowledge and understanding of proteins expressed by ticks. Ticks secrete immunosuppressant proteins that modulate the host’s immune system during blood feeding; these molecules ...
Martin Omulindi Oyugi, Johnson Kangethe Kinyua, Esther Nkirote Magiri, Milcah Wagio Kigoni, Evenilton Pessoa Costa, Naftaly Wang’ombe Githaka, David A. McClellan   +6 more
wiley   +1 more source

Analysis of the Role of Akirin Interactions with Nuclear Body Proteins During Myogenesis [PDF]

, 2021
Akirin is a highly conserved, small nuclear protein of indeterminate structure ubiquitously expressed in non-fungal eukaryotic species. It was first discovered in the innate immune response, but many other functions have since been found, including ...
Yorke, Laura
core   +2 more sources

Ubiquitin signalling in Drosophila innate immune responses

The FEBS Journal, Volume 291, Issue 20, Page 4397-4413, October 2024.
Drosophila innate immunity against bacterial infection relies on humoral responses regulated by the Imd and Toll pathways activating NF‐κB transcription factors, as well as JNK activation and JAK/STAT signalling. These pathways are characterised by E3 ligases and deubiquitinating enzymes that determine ubiquitination of signalling molecules followed by
Anna L. Aalto, Veera Luukkonen, Annika Meinander   +2 more
wiley   +1 more source

The use of cell and larval assays to identify target genes for RNA interference‐meditated control of the Australian sheep blowfly (Lucilia cuprina)

Pest Management Science, Volume 80, Issue 9, Page 4686-4698, September 2024.
Two research models for Lucilia cuprina targets screening were established. The results contribute to the development of sustainable RNAi mediated bio‐control strategies for this agricultural pest. Abstract BACKGROUND Flystrike, primarily caused by Lucilia cuprina, is a major health and welfare issue for sheep wool industries.
Yunjia Yang, Bing Zhang, Jiaxi Yong, Peter James, Zhi Ping Xu, Neena Mitter, Timothy J Mahony, Karishma T Mody   +7 more
wiley   +1 more source