Results 51 to 60 of about 551 (135)
CNS Neuroscience &Therapeutics, Volume 30, Issue 9, September 2024.Transcranial direct current stimulation treatment alleviates oxidative stress and activates Akirin2‐PTEN signaling pathway, and enhances the neuroprotective effect of isoflurane pretreatment on ischemic stroke, highlighting the potential of combination therapy for ischemic stroke.
Xiangyi Kong +9 more
wiley +1 more source
BMC Research Notes, 2011 Background Marbling defined by the amount and distribution of intramuscular fat, so-called Shimofuri, is an economically important trait of beef cattle in Japan.
Muramatsu Youji +7 more
doaj +1 more source
Akirin protein is broadly distributed throughout the genome.
, 2012 (A,B) Polytene chromosomes were prepared from wild-type larvae, immunostained with antibody against Akirin and counterstained with DAPI to visualize DNA.
Hitoshi Aihara (180458) +4 more
core +1 more source
Identification of a candidate akirin enhancer sequence
Akirin, a small nuclear protein with conserved function across eukaryotes, is a critical determinant in the development of functional, robust cardiac and skeletal patterning and musculature.
Nowak, Scott J., DeSantis, Alyssa
core +2 more sources
Akirin‐1 expression blocks dexmethosone induced satellite cell dysfunction
The FASEB Journal, 2013 Glucocorticoids are elevated in many pathological conditions and are associated with muscle loss, but the mechanisms are not fully understood. Defects in satellite cell function contribute to the development of muscle atrophy. Here, we demonstrated a new mechanism of dexamethasone‐induced muscle atrophy by suppression of satellite ...
Yanjun Dong +4 more
openaire +1 more source
Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice [PDF]
Nature Immunology, 2007 During a genome-wide screen with RNA-mediated interference, we isolated CG8580 as a gene involved in the innate immune response of Drosophila melanogaster. CG8580, which we called Akirin, encoded a protein that acted in parallel with the NF-kappaB transcription factor downstream of the Imd pathway and was required for defense against Gram-negative ...
Tajima-Goto, Akira +9 more
openaire +2 more sources
Investigating the molecular function of Akirin during skeletal myogenesis in Drosophila melanogaster [PDF]
, 2018 The specification and differentiation of muscle precursor cells, or myoblasts, by the action of the mesodermal and muscle transcription regulator Twist is a key event in the formation of the Drosophila larval musculature.
Rowland, Kristina
core +2 more sources
Akirin interacts both genetically and physically with Twist.
, 2012 (A) Lateral views of stage 16 wild-type (wt) and embryos heterozygous for both twist and akirin (twi1/+; akirin2/+ and twi1/+; akirin3/+) stained with tropomyosin antibodies to visualize body wall muscles.
Hitoshi Aihara (180458) +4 more
core +1 more source
Analysis of novel heart defects in akirin mutants
, 2021 Among the metazoans the heart is one of the earliest discrete organ structures to form during embryogenesis, in a process highly conserved across the phyla.
core +2 more sources
Akirin specifies NF‐κB selectivity of Drosophila innate immune response via chromatin remodeling
The EMBO Journal, 2014 The network of NF-κB-dependent transcription that activates both pro- and anti-inflammatory genes in mammals is still unclear. As NF-κB factors are evolutionarily conserved, we used Drosophila to understand this network. The NF-κB transcription factor Relish activates effector gene expression following Gram-negative bacterial immune challenge. Here, we
Bonnay, François +8 more
openaire +3 more sources