Results 51 to 60 of about 513 (121)

Hyd ubiquitinates the NF-κB co-factor Akirin to activate an effective immune response in Drosophila

, 2018
One Sentence SummaryUpon microbial infection in Drosophila, the E3-ubiquitin ligase Hyd ubiquitinylates the NF-κB co-factor Akirin for its efficient binding to the NF-κB factor Relish and subsequent activation of immune effectors genes.ABSTRACTThe ...
Marie-Odile Fauvarque, François Bonnay, Akira Goto, Jean-Marc Reichhart, Amir Orian, Nicolas Matt, Xuan-Hung Nguyen, Michael Boutros, Alexandre Cammarata-Mouchtouris   +8 more
core   +1 more source

The Role of Akirin and Its Conserved SYLS Motif in Muscle Development

Akirin is a small protein involved in diverse processes, from mounting immune response to tissue development and nuclear trafficking. A mechanistic model that could explain such variety remains elusive.
Akter, Shaila
core  

Drosophila as a Model Organism to Study Basic Mechanisms of Longevity. [PDF]

Int J Mol Sci, 2022
Ogienko AA, Omelina ES, Bylino OV, Batin MA, Georgiev PG, Pindyurin AV.   +5 more
europepmc   +1 more source

Nuclear destruction: A suicide mission by AKIRIN2 brings intact proteasomes into the nucleus. [PDF]

Mol Cell, 2022
Chen X, Walters KJ.
europepmc   +1 more source

Function of cofactor Akirin2 in the regulation of gene expression in model human Caucasian neutrophil-like HL60 cells. [PDF]

Biosci Rep, 2021
Artigas-Jerónimo S, Villar M, Estrada-Peña A, Velázquez-Campoy A, Alberdi P, de la Fuente J.   +5 more
europepmc   +1 more source

Characterising the effect of Akirin knockdown on Anopheles arabiensis (Diptera: Culicidae) reproduction and survival, using RNA-mediated interference. [PDF]

PLoS One, 2020
Letinić BD, Dahan-Moss Y, Koekemoer LL.
europepmc   +1 more source

Tick Vaccines and Concealed versus Exposed Antigens. [PDF]

Pathogens, 2023
Antunes S, Domingos A.
europepmc   +1 more source

Examining genetic interactions between the akirin and MTA-Like loci for cardiac and skeletal muscle development​

Congenital heart disease is a cardiac abnormality that is caused due to improper development of the heart. The severity of heart defects this disease produces can range from minor to severe, with some of the most severe cases being deformed or missing ...
Craft, Ariana, Nowak, Scott
core   +1 more source

Applying genome editing to modify the Akirin gene in the fruit fly for research

The highly conserved gene Akirin is present in flies and humans and regulates a variety of processes, from immune responses to muscle development. However, the regulatory mechanisms governing its expression and function remain largely unexplored.
Akter, Shaila, Bryantsev, Anton
core   +1 more source

Correction: Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila. [PDF]

PLoS Pathog
Cammarata-Mouchtouris A, Nguyen XH, Acker A, Bonnay F, Goto A, Orian A, Fauvarque MO, Boutros M, Reichhart JM, Matt N.   +9 more
europepmc   +1 more source