Acute hypoxia stress mediates HIF-1α-Yki-Cactus axis to facilitate the infection of Vibrio parahaemolyticus in Litopenaeus vannamei [PDF]
Frontiers in ImmunologyIntroductionHypoxia stress renders aquatic animals more susceptible to bacterial disease, yet the underlying mechanism remains elusive.MethodsWe conducted an acute hypoxia stress experiment to investigate the impact of stress on the immune response of ...
Honghui He +18 more
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Identification and comparative analysis of subolesin/akirin ortholog from Ornithodoros turicata ticks [PDF]
Parasites & Vectors, 2015 Background Subolesin is an evolutionary conserved molecule in diverse arthropod species that play an important role in the regulation of genes involved in immune responses, blood digestion, reproduction and development.
Hameeda Sultana +3 more
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The biological role of akirin in anopheles arabiensis
, 2020 A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Faculty of Health Sciences, School of Pathology, University of the Witwatersrand, Johannesburg, 2020Anopheles arabiensis is an opportunistic malaria ...
Letinić, Blaženka Danica
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Reduction in Oviposition of Poultry Red Mite (Dermanyssus gallinae) in Hens Vaccinated with Recombinant Akirin [PDF]
Vaccines, 2019 The poultry red mite (PRM), Dermanyssus gallinae, is a hematophagous ectoparasite of birds with worldwide distribution that causes economic losses in the egg-production sector of the poultry industry.
Jose Francisco Lima-Barbero +10 more
doaj +4 more sources
Association of a single nucleotide polymorphism in
BMC Research Notes, 2009 Background Marbling defined by the amount and distribution of intramuscular fat, so-called Shimofuri, is an economically important trait of beef cattle in Japan.
Takahagi Youichi +10 more
doaj +3 more sources
Akirin proteins in development and disease: critical roles and mechanisms of action. [PDF]
Cell Mol Life Sci, 2020 The Akirin genes, which encode small, nuclear proteins, were first characterized in 2008 in Drosophila and rodents. Early studies demonstrated important roles in immune responses and tumorigenesis, which subsequent work found to be highly conserved.
Bosch PJ +3 more
europepmc +4 more sources
The gut commensal bacterium Enterococcus faecalis LX10 contributes to defending against Nosema bombycis infection in Bombyx mori. [PDF]
Pest Manag Sci, 2022 According to the microsporidia–Bombyx mori model, we revealed that Enterococcus with anti‐Nosema bombycis activity might play an important role in protecting silkworms from microsporidia. The present study provides a clear profile of the complex interplay among microsporidia, silkworms, and gut microbiome.
Zhang X +7 more
europepmc +2 more sources
Roles of Akirin1 in early prediction and treatment of graft kidney ischemia‒reperfusion injury. [PDF]
Smart MedProposed model for how UM‐EVs mitigate ferroptosis and protect against graft kidney IRI. Akirin1, which is prominently elevated in the kidney IRI process, promotes EGR1‐mediated TP53 expression and suppresses MDM2‐mediated TP53 ubiquitination and degradation, accordingly upregulating TP53 in two ways.
Li X +16 more
europepmc +2 more sources
Investigation into the Akirin Subcellular Localization and Developmental Interactions [PDF]
, 2021 Akirin is a highly conserved nuclear protein ubiquitously expressed in nonfungal eukaryotic species and is known to be involved in many biological processes such as embryonic muscle patterning and innate immune function. Akirin functionality is essential
Wildeman, Riley
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BioArchitecture, 2012 Embryonic patterning relies upon an exquisitely timed program of gene regulation. While the regulation of this process via the action of transcription factor networks is well understood, new lines of study have highlighted the importance of a concurrently regulated program of chromatin remodeling during development.
Nowak, Scott J., Baylies, Mary K.
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