Results 21 to 30 of about 513 (121)

Reduction in Oviposition of Poultry Red Mite (Dermanyssus gallinae) in Hens Vaccinated with Recombinant Akirin [PDF]

open access: yesVaccines, 2019
The poultry red mite (PRM), Dermanyssus gallinae, is a hematophagous ectoparasite of birds with worldwide distribution that causes economic losses in the egg-production sector of the poultry industry. Traditional control methods, mainly based on acaricides, have been only partially successful, and new vaccine-based interventions are required for the ...
Jose Lima-Barbero   +10 more
openaire   +5 more sources

The biological role of akirin in anopheles arabiensis

open access: yes, 2020
A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Faculty of Health Sciences, School of Pathology, University of the Witwatersrand, Johannesburg, 2020Anopheles arabiensis is an opportunistic malaria ...
Letinić, Blaženka Danica
core   +2 more sources

Identification, Expression, Characteristic Analysis, and Immune Function of Two Akirin Genes in Grass Carp (Ctenopharyngodon idella) [PDF]

open access: yesAnimals (Basel)
Intensive aquaculture of grass carp often leads to decreased immunity and increased disease prevalence, resulting in economic losses. Improving grass carp immunity is therefore a critical strategy for addressing these challenges.
Boya Yang   +9 more
core   +2 more sources

Evolution of the multifaceted eukaryotic akirin gene family [PDF]

open access: yesBMC Evolutionary Biology, 2009
Akirins are nuclear proteins that form part of an innate immune response pathway conserved in Drosophila and mice. This studies aim was to characterise the evolution of akirin gene structure and protein function in the eukaryotes.akirin genes are present throughout the metazoa and arose before the separation of animal, plant and fungi lineages.
Macqueen, Daniel J, Johnston, Ian A
openaire   +5 more sources

Mosquito Akirin as a potential antigen for malaria control [PDF]

open access: yesMalaria Journal, 2014
The control of vector-borne diseases is important to improve human and animal health worldwide. Malaria is one of the world's deadliest diseases and is caused by protozoan parasites of the genus Plasmodium, which are transmitted by Anopheles spp. mosquitoes.
da Costa, Mário   +8 more
openaire   +3 more sources

Evolutionary plasticity in the innate immune function of Akirin [PDF]

open access: yesPLOS Genetics, 2017
ABSTRACT Eukaryotic gene expression requires the coordinated action of transcription factors, chromatin remodelling complexes and RNA polymerase. The conserved nuclear protein Akirin plays a central role in immune gene expression in insects and mammals, linking the SWI/SNF chromatin-remodelling complex with the ...
Jolanta Polanowska   +9 more
openaire   +5 more sources

Subolesin/Akirin Vaccines for the Control of Arthropod Vectors and Vectorborne Pathogens [PDF]

open access: yesTransboundary and Emerging Diseases, 2013
Diseases transmitted by arthropod vectors such as mosquitoes, ticks and sand flies greatly impact human and animal health, and therefore, their control is important for the eradication of vectorborne diseases (VBD). Vaccination is an environmentally friendly alternative for vector control that allows control of several VBD by targeting their common ...
Fuente, José de la   +8 more
openaire   +3 more sources

A Novel Combined Scientific and Artistic Approach for the Advanced Characterization of Interactomes: The Akirin/Subolesin Model [PDF]

open access: yesVaccines, 2020
The main objective of this study was to propose a novel methodology to approach challenges in molecular biology. Akirin/Subolesin (AKR/SUB) are vaccine protective antigens and are a model for the study of the interactome due to its conserved function in the regulation of different biological processes such as immunity and development throughout the ...
Sara Artigas-Jerónimo   +11 more
openaire   +7 more sources

Identification and comparative analysis of subolesin/akirin ortholog from Ornithodoros turicata ticks [PDF]

open access: yesParasites & Vectors, 2015
Subolesin is an evolutionary conserved molecule in diverse arthropod species that play an important role in the regulation of genes involved in immune responses, blood digestion, reproduction and development. In this study, we have identified a subolesin ortholog from soft ticks Ornithodoros turicata, the vector of the relapsing fever spirochete in the
Sultana, Hameeda   +3 more
openaire   +4 more sources

Tick subolesin is an ortholog of the akirins described in insects and vertebrates

open access: yesDevelopmental & Comparative Immunology, 2009
The tick protective antigen, subolesin, is a regulatory protein involved in the control of multiple cellular pathways. Subolesin is evolutionary conserved in invertebrates and vertebrates with sequence homology to akirins, a recently renamed group of proteins that were proposed to function as transcription factors in Drosophila and mice.
Galindo, Ruth C.   +8 more
openaire   +4 more sources

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