Results 11 to 20 of about 513 (121)

Role of Akirin in Skeletal Myogenesis [PDF]

International Journal of Molecular Sciences, 2013
Akirin is a recently discovered nuclear factor that plays an important role in innate immune responses. Beyond its role in innate immune responses, Akirin has recently been shown to play an important role in skeletal myogenesis.
Guangmang Liu, Gang Jia, Xiulan Guo, Zhiqing Huang, Renyong Tang, Xiaoling Chen, Dingbiao Long, Huan Wang   +7 more
core   +5 more sources

Akirin is Critical for Early tinman Induction and Subsequent Formation of the Heart in Drosophila melanogaster [PDF]

Developmental Biology, 2021
The regulation of formation of the Drosophila heart by the Nkx 2.5 homologue Tinman is a key event during embryonic development. In this study, we identify the highly conserved transcription cofactor Akirin as a key factor in the earliest induction of ...
Hupp, Madison, Nowak, Scott J., Howard, Austin, Milner, Hayley, Willett, Courtney, Palermino, Kristina   +5 more
core   +4 more sources

Additional evidence on the efficacy of different Akirin vaccines assessed on Anopheles arabiensis (Diptera: Culicidae) [PDF]

Parasites & Vectors, 2021
[Background]: Anopheles arabiensis is an opportunistic malaria vector that rests and feeds outdoors, circumventing current indoor vector control methods. Furthermore, this vector will readily feed on both animals and humans.
Fuente, José de la, Koekemoer, Lizette L., Letinić, Blaženka D., Linnekugel, Ingrid, Dahan-Moss, Yael, Contreras, Marinela, Lizette L. Koekemoer, Blaženka D. Letinić, Ingrid Linnekugel, José de la Fuente, Yael Dahan-Moss, Marinela Contreras   +11 more
core   +6 more sources

Role of nuclear protein Akirin in the modulation of female reproduction in Nilaparvata lugens (Hemiptera: Delphacidae) [PDF]

Frontiers in Physiology
Introduction: Akirin as a highly conserved transcription factor, exerts a profound influence on the growth, development, immune response, and reproductive processes in animals. The brown planthopper (BPH), Nilaparvata lugens, a major pest in rice production in Asia, possesses high reproductive capacity, a critical factor contributing to reduced rice ...
Feiyan Gou, Daowei Zhang, Siqi Chen, Mingjing Zhang, Jing Chen   +4 more
exaly   +6 more sources

Characterization of the Akirin Gene and Its Role in the NF-κB Signaling Pathway of Sogatella furcifera [PDF]

Frontiers in Physiology, 2018
Akirin is an essential nuclear protein involved in the regulation of NF-κB signaling pathway. In most invertebrates, Akirin regulates NF-κB-related Imd and Toll pathways, however, in Drosophila, it only controls the Imd pathway, whereas its role in NF-κB signaling pathway in other insect species is unclear.
Jing Chen, Dao-Wei Zhang, Xing Jin, Xian-Lin Xu, Bo-Ping Zeng   +4 more
exaly   +6 more sources

Akirin proteins in development and disease: critical roles and mechanisms of action [PDF]

Cellular and Molecular Life Sciences, 2020
The Akirin genes, which encode small, nuclear proteins, were first characterized in 2008 in Drosophila and rodents. Early studies demonstrated important roles in immune responses and tumorigenesis, which subsequent work found to be highly conserved.
Peter J. Bosch, Stacey L. Peek, Sarit Smolikove, Joshua A. Weiner   +3 more
openaire   +3 more sources

Akirin [PDF]

BioArchitecture, 2012
Embryonic patterning relies upon an exquisitely timed program of gene regulation. While the regulation of this process via the action of transcription factor networks is well understood, new lines of study have highlighted the importance of a concurrently regulated program of chromatin remodeling during development.
Nowak, Scott J., Baylies, Mary K.
openaire   +5 more sources

Association of the SNP in akirin 2 Gene With Growth and Carcass Traits in Zavot Cattle [PDF]

Veterinary Medicine and Science
ABSTRACTUnderstanding the genetic factors that influence meat yield is crucial due to the economic importance of average daily live weight gain (ADWG) in livestock. This study investigates the relationship between the c.*188G>A SNP in the 3′‐UTR region of the akirin 2 gene and growth traits in Zavot cattle, focusing on the gene's role in muscle ...
Osman Tufan Ertan, Yunus Arzik, Fadime Daldaban, Korhan Arslan, Bilal Akyuz   +4 more
openaire   +5 more sources

Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila [PDF]

PLOS Pathogens, 2020
La vía de la inmunodeficiencia (IMD) en Drosophila melanogaster se activa tras la exposición microbiana a bacterias gramnegativas para desencadenar la respuesta inmune innata. Para descifrar esta vía de señalización del factor nuclear κB (NF-κB), realizamos un cribado de ARNi in vitro dirigido específicamente a las ubiquitina ligasas E3 e identificamos
Alexandre Cammarata-Mouchtouris, Xuan‐Hung Nguyen, Adrian Acker, François Bonnay, Ayumu Goto, Amir Orian, Marie-Odile Fauvarque, Michael Boutros, Jean‐Marc Reichhart, Nicolas Matt   +9 more
openaire   +6 more sources

Characterization of Aedes albopictus akirin for the control of mosquito and sand fly infestations

Vaccine, 2010
The control of arthropod vectors of pathogens that affect human and animal health is important for the eradication of vector-borne diseases. Recent evidences showed a reduction in the survival and/or fertility of mosquitoes, sand flies and poultry red mites fed in vitro with antibodies against the recombinant Aedes albopictus akirin.
Moreno-Cid, J. A., Jimenez, M., /Cornélie, Sylvie, Molina, R., Alarcon, P., Lacroix, M. N., Pinal, R., Delacour, S., Lucientes, J., Canales, M., de la Lastra, J. M. P., Villar, M., de la Fuente, J.   +12 more
openaire   +5 more sources