Results 101 to 110 of about 573,336 (261)
Neuropsychiatric Disease and Treatment, 2021 Wei Zeng,1,2 Chunyuan Zhang,2 Qingshan Long,3 Yalan Li1 1Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong, People’s Republic of China; 2Department of Anesthesiology, Affiliated Boai ...
Zeng W, Zhang C, Long Q, Li Y
doaj
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Exquisit schnelläufer Schnellpressenfabrik Akt. Ges. Heidelberg
EXQUISIT SCHNELLÄUFER SCHNELLPRESSENFABRIK AKT. GES. HEIDELBERG Exquisit schnelläufer Schnellpressenfabrik Akt. Ges. Heidelberg ( -
Schnellpressenfabrik Akt. Ges.
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Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes [PDF]
, 2010 名古屋大学NAGOYA University博士(リハビリテーション療法学)Skeletal muscle cells are hypertrophied by mechanical stresses, but the underlying molecular mechanisms are not fully understood.
SASAI, NOBUAKI, 笹井, 宣昌
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Repetitive Stretching Prevents Muscle Atrophy in Denervated Soleus Muscle via Akt/mTOR/p70S6K Pathways [PDF]
, 2009 名古屋大学NAGOYA University博士(医療技術学)This study was conducted to examine whether stretch-related mechanical loading on skeletal muscle can suppress denervation-induced muscle atrophy, and if so, to depict the underlying molecular mechanism.
Agata, Nobuhide, 縣, 信秀
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EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells [PDF]
, 2009 The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma.
Jauch, Karl-Walter +8 more
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Advanced Functional Materials, EarlyView.This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu +14 more
wiley +1 more source
B7-H3 Induces Ovarian Cancer Drugs Resistance Through An PI3K/AKT/BCL-2 Signaling Pathway
Cancer Management and Research, 2019 Li Zhou,1 Yangchun Zhao2 1Department of Gynecology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of Obstetrics and Gynecology, The Second Affiliated ...
Zhou L, Zhao Y
doaj
, 2018 Figure S2 Total AKT level is not changed in Mig-6 d/d mice after P4 treatment. (A) The expression of AKT in the uteri of vehicle (a) and P4 (b) treated Mig-6 d/d mice and (B) H-score of AKT in the uteri of vehicle and P4 treated Mig-6 d/d mice. (PPTX 407
Jung-Yoon Yoo (462528) +5 more
core +1 more source