Results 81 to 90 of about 532,309 (312)
AKT signaling mediates IGF-I survival actions on otic neural progenitors
, 2012 Background: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes.
Sanchez-Calderon, Hortensia +19 more
core +1 more source
Lukijatutkimus AKT-lehdelle [PDF]
, 2023 Järjestölehdille on erityisen tärkeää tuntea lukijakuntansa, sekä mitä he haluavat lehdeltä. Tutkimalla lehden lukijoita ja palautetta keräämällä pyritään tilanteeseen, jossa lehden lukijat ovat mahdollisimman tyytyväisiä.
Iivari, Arttu
core
Cancer Biology & Medicine, 2020 Objective: Heat shock protein 47 (HSP47) is a collagen-specific molecular chaperone that facilitates collagen maturation. Its role in cancer remains largely unknown.
Yijye Chern +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells
, 2017 Mouse embryonic stem cells (ES cells) can proliferate indefinitely. To identify potential signals involved in suppression of self-renewal, we previously screened a kinase/phosphatase expression library in ES cells, and observed that inhibition of Dual ...
呂立 +1 more
core +1 more source
Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]
, 2008 To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Chan, W-C. +11 more
core +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
TLR3-mediated apoptosis and activation of phosphorylated Akt in the salivary gland epithelial cells of primary Sjögren’s syndrome patients [PDF]
, 2013 This study aimed at ascertain whether innate immunity is involved in the apoptosis of primary cultured salivary gland epithelial cells (SGECs) in primary Sjögren's syndrome (pSS). Induction of apoptosis of SGECs was performed using a TLR3 ligand, poly (I:
Horai, Yoshiro +7 more
core +1 more source
Archiwa - Kancelarie - Zbiory, 2015 Artykuł omawia dzieje oraz zawartość kolekcji dokumentacji technicznej z lat 1919–1939, wchodzącej w skład przechowywanego w zasobie Archiwum Akt Nowych zespołu akt Ministerstwa Spraw Wewnętrznych w Warszawie 1918–1939.
Adam Grzegorz Dąbrowski
doaj
Phosphorylation of Akt at the C-terminal tail triggers Akt Activation [PDF]
Cell Cycle, 2014 Aberrant hyper-activation of the protein kinase Akt plays a critical role in promoting tumorigenesis. Mechanistically, previous studies establish that phosphorylation of Akt at S473 and T308 by mTORC2 and PDK1, respectively, is necessary for its full activation, thereby having been used as Akt activation markers.
Pengda, Liu, Zhiwei, Wang, Wenyi, Wei
openaire +2 more sources