Results 281 to 290 of about 972,716 (314)
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Science Signaling, 2012
ATP and ADP regulate a conformational switch that determines the kinase activity of Akt.
Sean J, Humphrey, David E, James
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ATP and ADP regulate a conformational switch that determines the kinase activity of Akt.
Sean J, Humphrey, David E, James
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Current Topics in Medicinal Chemistry, 2020
Cancer is a devastating disease that has plagued humans from ancient times to this day. After decades of slow research progress, promising drug development, and the identification of new targets, the war on cancer was launched, in 1972. The P13K/Akt pathway is a growth-regulating cellular signaling pathway, which in many human cancers is over ...
Nne E, Uko +3 more
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Cancer is a devastating disease that has plagued humans from ancient times to this day. After decades of slow research progress, promising drug development, and the identification of new targets, the war on cancer was launched, in 1972. The P13K/Akt pathway is a growth-regulating cellular signaling pathway, which in many human cancers is over ...
Nne E, Uko +3 more
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2018
AKT is a serine/threonine kinase member of the AGC family of protein kinases. The three isoforms of AKT (AKT1/2/3) play a central role in growth, proliferation, glucose uptake, metabolism, protein translation and cell survival. Given the importance of the AKT pathway in all these processes it is not surprising that its deregulation is associated with a
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AKT is a serine/threonine kinase member of the AGC family of protein kinases. The three isoforms of AKT (AKT1/2/3) play a central role in growth, proliferation, glucose uptake, metabolism, protein translation and cell survival. Given the importance of the AKT pathway in all these processes it is not surprising that its deregulation is associated with a
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2000
An increasing number of publications have underscored the importance of the serine/threonine kinase Akt in the regulation of cell survival, proliferation, and insulin-dependent metabolic cell responses. Critical to the understanding of Akt signaling in cells are experimental methods that assess its activation and phosphorylation state. In this chapter,
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An increasing number of publications have underscored the importance of the serine/threonine kinase Akt in the regulation of cell survival, proliferation, and insulin-dependent metabolic cell responses. Critical to the understanding of Akt signaling in cells are experimental methods that assess its activation and phosphorylation state. In this chapter,
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Knidia oder: Des Aktes erster Akt
2016kritische berichte - Zeitschrift für Kunst- und Kulturwissenschaften, Bd. 17, Nr.
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