Results 171 to 180 of about 79,953 (279)

Tau PET overlap index correlation with neuropathological findings

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.
Seokbeen Lim, Jeyeon Lee, Paul H. Min, Christina M. Moloney, Carly T. Mester, Sujala Ghatamaneni, Matthew L. Senjem, Hugo Botha, David S. Knopman, Stuart J. McCarter, Vijay K. Ramanan, Rodolfo Savica, Julie A. Fields, Mary M. Machulda, Dennis W. Dickson, R. Ross Reichard, Aivi T. Nguyen, Jonathan Graff‐Radford, Christopher G. Schwarz, Jeffrey L. Gunter, Kejal Kantarci, Bradley Boeve, Prashanthi Vemuri, David T. Jones, Clifford R. Jack Jr., Ronald C. Petersen, Melissa E. Murray, Val J. Lowe   +27 more
wiley   +1 more source

Concurrent TTR and AL Amyloidosis: Diagnostic Challenges and Clinical Implications. [PDF]

JACC Case Rep
Wats K, Chakraborty R, Navarro-Torres M, Siegelin MD, D'Agati VD, Maurer MS.   +5 more
europepmc   +1 more source

Obstructive sleep apnea severity, Alzheimer's disease plasma markers, and CSF brain amyloidosis and tau pathology

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION We examined obstructive sleep apnea (OSA) severity's association with Alzheimer's disease (AD) plasma biomarkers, independent or synergistic with cerebrospinal fluid (CSF) amyloid, and as a proof of concept, whether plasma amyloid beta (Aβ)42/Aβ40 with OSA severity improves detection of amyloidosis and tau pathology.
Omonigho Michael Bubu, Anna E. Mullins, Shreshtha Shah, Joshua L. Gills, Korey Kam, Ankit Parekh, Ogie Q. Umasabor‐Bubu, Arlener D. Turner, Mark Bernard, Anthony Briggs, Jaime Ramos‐Cejudo, Elena Valkanova, Alfred K. Mbah, Purbanka Pahari, Ludovic Debure, Mobeena Ghuman, Allal Boutajangout, Natasha J. Williams, Jeongyeon Hwang, Masrai K. Williams, David M. Rapoport, Indu Ayappa, Mony de Léon, Girardin Jean‐Louis, Andrew W. Varga, Ricardo S. Osorio   +25 more
wiley   +1 more source

Case Report: Contrast adenosine stress echocardiography revealing microvascular dysfunction in cardiac AL amyloidosis. [PDF]

Front Cardiovasc Med
Dai Y, Deng Y, Lin N, Che F, Li C, Yin L.   +5 more
europepmc   +1 more source

Genetic correlation analysis identifies TMEM106B, ACE, and ERC2 as genetic loci shared between Alzheimer's disease and primary psychiatric disorders

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Neuropsychiatric symptoms (NPSs) occur in up to 85% of Alzheimer's disease (AD) cases. Current treatments – repurposed from psychiatric disorders despite limited understanding of etiologic overlap – are often ineffective. METHODS To characterize the genetic overlap between AD and major psychiatric disorders and identify shared ...
Ajneesh Kumar, Nicholas R. Ray, Jiji T. Kurup, Pamela Del Rosario, Masood Manoochehri, Colin Stein, Alyssa N. De Vito, Brenna Cholerton, Robert A. Sweet, Phil L. de Jager, Hans‐Ulrich Klein, Michael L. Cuccaro, Gary W. Beecham, Edward D. Huey, Christiane Reitz   +14 more
wiley   +1 more source

Clinical significance of t(11;14) translocation in systemic AL amyloidosis in the era of daratumumab therapy. [PDF]

Clin Exp Med
Nishimura N, Kawano Y, Yasunaga JI.
europepmc   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae, Jessica Marie Hunter Alberhasky, Marion Baillet, Debra A. Bangasser, Michael E. Belloy, Anne S. Berry, Chiara Berteotti, Hannah Bow, Rachel Buckley, Jessica Z. K. Caldwell, Matteo Carpi, Benjamin J. Clark, Claire J. Ciampa, Alexander C. Conley, Martin J. Dahl, Zoe R. Donaldson, Alexander J. Ehrenberg, Gillian Einstein, Neus Falgàs, Haley A. Fenlon, Megan C. Fitzhugh, Robert C. Froemke, Clara Gallay, Lea Tenenholz Grinberg, Derek A. Hamilton, Zia Hasan, Oihane Uriarte Huarte, Shaista Jabeen, Heidi I. L. Jacobs, Louis John Kolling, Elouise A. Koops, Sabrina Lenzoni, Claudio Liguori, Riccardo Manca, Catherine A. Marcinkiewcz, Tamunotonye Omoluabi, Rademene Oria, Caitlin A. Orsini, Nancy Elizabeth Ortega, Judy Pa, Nathan S. Pentkowski, Joana B. Pereira, Rhudovic Ramos, Derya Sargin, Abhijit Satpati, Maria Clara Selles, Mabel Seto, Shabana M. Shaik, Shireen Sindi, Gowoon Son, Valentine Ucheagwu, Maxime Van Egroo, Qi Yuan, Michael A. Kelberman   +53 more
wiley   +1 more source

Serum and Tissue Light-Chains as Disease Biomarkers in AL Amyloidosis. [PDF]

Int J Mol Sci
Aimo A, Ferrari Chen YF, Chianca M, Mori F, Pucci A, Castiglione V, Musetti V, Caponi L, Fabiani I, Vergaro G, Franzini M, Emdin M, Cardinale D.   +12 more
europepmc   +1 more source

Myocardial deformation imaging to monitor treatment response in AL amyloidosis: is it worth the strain? [PDF]

Eur Heart J Open
Castiglione V, Gentile F, Vergaro G.
europepmc   +1 more source

Renal‐Limited Thrombotic Microangiopathy due to Anti‐VEGF/TKI Immunotherapy for Metastatic Renal Cell Carcinoma Presenting as Nephrotic Syndrome: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Vascular endothelial growth factor (VEGF) inhibition may result in proteinuria, worsening hypertension, chronic kidney injury, or glomerular disease. Recently, systemic VEGF inhibition has been reported to cause nephrotic disorders and thrombotic microangiopathy (TMA).
Sundus Sardar, Ahmad Matarneh, Omar K. Salameh, Abdel‐Rauof M. Akkari, Monika Joshi, Erik Washburn, Nasrollah Ghahramani, Naman Trivedi   +7 more
wiley   +1 more source