Results 11 to 20 of about 54,210 (294)

Expert recommendation from the Swiss Amyloidosis Network (SAN) for systemic AL-amyloidosis [PDF]

Swiss Medical Weekly, 2020
Systemic amyloidosis is a heterogeneous group of diseases associated with protein misfolding into insoluble beta-sheet rich structures that deposit extracellularly in different organs, eventually compromising their function.
Rahel Schwotzer, Andreas J. Flammer, Sabine Gerull, Thomas Pabst, Paolo Arosio, Manuela Averaimo, Ulrike Bacher, Peter Bode, Andrea Cavalli, Adalgisa Condoluci, Stefan Dirnhofer, Nadia Djerbi, Stephan W. Dobner, Thomas Fehr, Maura Garofalo, Ariana Gaspert, Raphael Heimgartner, Annemarie Hübers, Hans H. Jung, Chiara Kessler, Raphael Knöpfel, Natallia Laptseva, Robert Manka, Luca Mazzucchelli, Martin Meyer, Violeta Mihaylova, Pierre Monney, Alessio Mylonas, René Nkoulou, Aju P. Pazhenkottil, Otmar Pfister, Axel Rüfer, Adrian Schmidt, Harald Seeger, Simon F. Stämpfli, Guido Stirnimann, Thomas Suter, Marie Théaudin, Giorgio Treglia, Alexandar Tzankov, Friederike Vetter, Markus Zweier, Bernhard Gerber   +42 more
doaj   +4 more sources

Misdiagnosis of Hereditary Amyloidosis as AL (Primary) Amyloidosis [PDF]

New England Journal of Medicine, 2002
Hereditary, autosomal dominant amyloidosis, caused by mutations in the genes encoding transthyretin, fibrinogen A alpha-chain, lysozyme, or apolipoprotein A-I, is thought to be extremely rare and is not routinely included in the differential diagnosis of systemic amyloidosis unless there is a family history.We studied 350 patients with systemic ...
Lachmann, H.J., Booth, D.R., Booth, S.E., Bybee, A., Gilbertson, J.A., Gillmore, J.D., Pepys, M.B., Hawkins, P.N.   +7 more
openaire   +4 more sources

A Case of Systemic AL Amyloidosis Diagnosed by Screening Colonoscopy

Case Reports in Gastrointestinal Medicine, 2022
Amyloidosis encompasses several diseases associated with deposition of low-molecular-weight proteins in an abnormal configuration. In light-chain amyloidosis (AL), monoclonal free lambda (λ) or kappa (κ) light chains are the amyloid proteins involved and
Lynna Alnimer, Ali Zakaria, Jalpa Patel, Yazan Samhouri, Samira Ahsan, Lyle Goldman, Serge Sorser   +6 more
doaj   +2 more sources

Gastroparesis in a Patient with Gastric AL Amyloidosis

Case Reports in Gastroenterology, 2018
Systemic amyloidosis is a group of complex disorders characterized by the extracellular deposition of nonbranching fibrils in various tissues, ultimately leading to a variety of clinical presentations including isolated or multiorgan dysfunction. Amyloid
Matthew Hoscheit, Afrin Kamal, Michael Cline   +2 more
doaj   +2 more sources

Real‐World Diagnostic Workup of Patients Suspected for Light Chain Amyloidosis and Wild‐Type Transthyretin Amyloid Cardiomyopathy: A Retrospective Cohort Study Using US Electronic Health Records

eJHaem
Introduction Light chain (AL) amyloidosis and transthyretin amyloid cardiomyopathy (ATTR‐CM) are the most common types of cardiac amyloidosis. Despite similar manifestations, prognosis and treatments are distinct, emphasizing the importance of accurate ...
Muhamed Baljevic, Haechung Chung, Jose Alvir, Patrick Feron, Aaron Crowley, Darrin Benjumea, Yong Chen, Cindi Pankratova   +7 more
doaj   +2 more sources

AL amyloidosis enhances development of amyloid A amyloidosis [PDF]

British Journal of Dermatology, 2007
Contains fulltext : 52125.pdf (Publisher’s version ) (Open Access)
Hilst, J.C.H. van der, Meer, J.W.M. van der, Drenth, J.P.H., Simon, A.   +3 more
openaire   +1 more source

Dysregulation of miRNAs In AL Amyloidosis [PDF]

Blood, 2010
Abstract Abstract 4648 Bone marrow plasma cells (BMPC) were purified from aspirates obtained from patients with AL amyloidosis using anti-CD138 immunomagnetic beads, and from controls. Expression levels of micro RNAs (miRNAs) were compared by microarray.
Liangping, Weng, Brian H, Spencer, Pamela T, SoohHoo, Lawreen H, Connors, Carl J, O'Hara, David C, Seldin   +5 more
openaire   +2 more sources

Severe Obstructive Cholestasis and Hypercalcemia Caused by Light-Chain Amyloidosis: A Case Report [PDF]

Iranian Journal of Medical Sciences, 2022
Gastrointestinal amyloidosis is a condition caused by the deposition of extracellular protein fragments. It can be associated with complex and diverse pathways and can have numerous manifestations and etiologies.
Zahra Davoudi, Farahnaz Bidari, Elena Jamali, Shahriar Nikpour   +3 more
doaj   +1 more source

Be SMART About AL Amyloidosis [PDF]

Mayo Clinic Proceedings, 2021
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Palladini, Giovanni, Merlini, Giampaolo
openaire   +4 more sources

Structural analysis of ex vivo amyloid fibrils from AL amyloidosis

, 2023
The disease AL amyloidosis is caused by the misfolding of immunoglobulin light chains (LC). Due to an underlying plasma cell dyscrasia, amyloidogenic LCs are overproduced and their high serum concentrations lead to aggregation and amyloid fibril ...
Radamaker, Lynn
core   +1 more source