Immunoglobulin Light Chain Amyloidosis
Waxy, purple nodules and plaques distributed across the distal fingers and thenar eminences. ABSTRACT Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon +3 more
wiley +1 more source
The molecular landscape of AL amyloidosis. [PDF]
Zvida-Bloch T +4 more
europepmc +1 more source
ABSTRACT Dialysis‐related amyloidosis (DRA) results from β2‐microglobulin accumulation in patients on long‐term hemodialysis, typically manifesting after 5–10 years. While well‐documented in developed countries, reports from sub‐Saharan Africa remain scarce.
Yannick Laurent Tchenadoyo Bayala +8 more
wiley +1 more source
Progressive Macroglossia and Dysphagia as the Initial Manifestation of Systemic Amyloid Light-Chain (AL) Amyloidosis Associated With Multiple Myeloma: A Case Report and Literature Review. [PDF]
Biswas N +4 more
europepmc +1 more source
Myocardial deformation imaging to monitor treatment response in AL amyloidosis: is it worth the strain? [PDF]
Castiglione V, Gentile F, Vergaro G.
europepmc +1 more source
Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo +3 more
wiley +1 more source
Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus‐Associated Disorders
ABSTRACT Background Kaposi sarcoma herpes virus (KSHV) is associated with multiple clinical manifestations, including primary effusion lymphoma, an aggressive CD38+ B cell lymphoma with a plasmablastic phenotype. Case This case describes an antiretroviral therapy‐adherent person with HIV who presented with concurrent KSHV‐related disorders of Kaposi ...
Kandice Roberts +13 more
wiley +1 more source
Hematologic response and kidney outcomes of monoclonal gammopathy of renal significance excluding AL amyloidosis: a report of six cases. [PDF]
Nobayashi H +9 more
europepmc +1 more source
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz +15 more
wiley +1 more source
Comparative evaluation of free light chain assays in AL amyloidosis: Performance of Sebia versus Freelite and N-Latex. [PDF]
Zhao F, Pretorius C, Mollee P.
europepmc +1 more source

