Results 211 to 220 of about 17,175,483 (375)
Magnetic Resonance in Medicine, EarlyView.Abstract Purpose To develop an experimental method for measuring the labeling efficiency of pseudo‐continuous arterial spin labeling (pCASL) MRI in mice. Methods We propose a method using bidirectional crusher gradients to modulate vascular signals in the azygos pericallosal artery (azPA) of the mouse brain, applied with and without pCASL labeling. The
Xiuli Yang +5 more
wiley +1 more source
Treatment options for severe cardiac amyloidosis: heart transplantation combined with chemotherapy and stem cell transplantation for patients with AL-amyloidosis and heart and liver transplantation for patients with ATTR-amyloidosis☆ [PDF]
, 2007 Falk‐Udo Sack +6 more
openalex +1 more source
Sural/Radial Amplitude Ratio: A Useful Tool to Diagnose Non‐Length‐Dependent Neuropathy
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Patients with non‐length‐dependent neuropathy (NLDN) exhibit reduced sensory nerve action potential (SNAP) amplitudes in both lower and upper limbs. This study aimed to determine a threshold for the sural/radial amplitude ratio (SRAR) suggestive of NLDN.
Antoine Pegat +6 more
wiley +1 more source
State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna +4 more
wiley +1 more source
Localized primary AL-type amyloidosis of the jejunum diagnosed by double-balloon enteroscopy [PDF]
, 2007 Michael Bellutti +6 more
openalex +1 more source
Effect of dialysate buffer on serum beta-2-microglobulin levels in chronic hemodialysis [PDF]
, 1998 Küchle, Claudius +2 more
core +1 more source
Small Science, EarlyView.Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello +5 more
wiley +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, EarlyView.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source