Results 51 to 60 of about 614,051 (372)

Chiral Symmetry Breaking in Magnetoelectrochemical Etching with Chloride Additives

Molecules, 2017
Magnetoelectrolysis (electrolysis under magnetic fields) produces chiral surfaces on metal thin films, which can recognize the enantiomers of amino acids.
Iwao Mogi, Ryoichi Aogaki, Kohki Takahashi   +2 more
doaj   +1 more source

Yield and Metabolite Production of Pelargonium sidoides DC. in Response to Irrigation and Nitrogen Management

Metabolites, 2020
Competition for water between agricultural and non-agricultural economic sectors hampers agricultural production, especially in water-scarce regions.
Motiki M. Mofokeng, Gerhard Prinsloo, Hintsa T. Araya, Christian P. du Plooy, Ntshakga R. Sathekge, Stephen O. Amoo, J. Martin Steyn   +6 more
doaj   +1 more source

Alanine aminotransferase controls seed dormancy in barley

Nature Communications, 2016
Dormancy allows wild barley grains to survive dry summers in the Near East. After domestication, barley was selected for shorter dormancy periods.
Kazuhiro Sato, M. Yamane, N. Yamaji, H. Kanamori, A. Tagiri, J. Schwerdt, G. Fincher, T. Matsumoto, K. Takeda, T. Komatsuda   +9 more
semanticscholar   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Combination of Alanine and Glutathione as Targeting Ligands of Nanoparticles Enhances Cargo Delivery into the Cells of the Neurovascular Unit

Pharmaceutics, 2020
Inefficient drug delivery across the blood–brain barrier (BBB) and into target cells in the brain hinders the treatment of neurological diseases. One strategy to increase the brain penetration of drugs is to use vesicular nanoparticles functionalized ...
Gergő Porkoláb, Mária Mészáros, András Tóth, Anikó Szecskó, András Harazin, Zsolt Szegletes, Györgyi Ferenc, András Blastyák, Lajos Mátés, Gábor Rákhely, Mária A. Deli, Szilvia Veszelka   +11 more
doaj   +1 more source

Utilization of amino acid for selective leaching of critical metals from spent hydrodesulfurization catalyst

Frontiers in Chemistry, 2022
While spent catalysts can cause serious environmental pollution, they can be considered an essential secondary metal source due to their high critical metal grades.
Idol Phann, Yu Tanaka, Sae Yamamoto, Naoko Okibe   +3 more
doaj   +1 more source

Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β‐alanine transamination

Journal of Physiology, 2016
Using recombinant DNA technology, the present study provides the first strong and direct evidence indicating that β‐alanine is an efficient substrate for the mammalian transaminating enzymes 4‐aminobutyrate‐2‐oxoglutarate transaminase and alanine ...
L. Blancquaert, S. Baba, S. Kwiatkowski, J. Stautemas, Sanne Stegen, S. Barbaresi, Weiliang Chung, A. Boakye, J. Hoetker, A. Bhatnagar, J. Delanghe, B. Vanheel, M. Veiga-da-Cunha, W. Derave, I. Everaert   +14 more
semanticscholar   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Markerless Mutagenesis inMethanococcus maripaludisDemonstrates Roles for Alanine Dehydrogenase, Alanine Racemase, and Alanine Permease [PDF]

Journal of Bacteriology, 2005
ABSTRACTAmong the archaea,Methanococcus maripaludishas the unusual ability to usel- ord-alanine as a nitrogen source. To understand how this occurs, we tested the roles of three adjacent genes encoding homologs of alanine dehydrogenase, alanine racemase, and alanine permease.
John A. Leigh, Brian C. Moore
openaire   +3 more sources

Interaction Entropy for Computational Alanine Scanning

Journal of Chemical Information and Modeling, 2017
The theoretical calculation of protein-protein binding free energy is a grand challenge in computational biology. Accurate prediction of critical residues along with their specific and quantitative contributions to protein-protein binding free energy is ...
Yuna Yan, Maoyou Yang, Changge Ji, J. H. Zhang   +3 more
semanticscholar   +1 more source