Results 121 to 130 of about 457,916 (395)
The Role of Structure in the Protein Dynamical Transition [PDF]
arXiv, 2008 The protein dynamical transition is investigated as a function of protein structure using terahertz time domain spectroscopy (THz-TDS). Measurements performed for native state and denatured hen egg white lysozyme (HEWL) show that protein structure is not necessary for the dynamical transition.
arxiv
Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]
, 2013 PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S +14 more
core +2 more sources
Open Heart, 2015 Objective Aspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio, reflecting liver disease severity, has been associated with increased risk of cardiovascular disease (CVD).
S. Weng, J. Kai, I. Guha, N. Qureshi
semanticscholar +1 more source
Advanced Materials, EarlyView.ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac +7 more
wiley +1 more source
Chiral selectivity of amino acid adsorption on chiral surfaces - the case of alanine on Pt [PDF]
, 2014 We study the binding pattern of the amino acid alanine on the naturally chiral Pt surfaces Pt(531), Pt(321) and Pt(643). These surfaces are all vicinal to the {111} direction but have different local environments of their kink sites and are thus a model for realistic roughened Pt surfaces.
arxiv +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos +5 more
wiley +1 more source
Fission of charged alanine dipeptides [PDF]
arXiv, 2004 In this work we have performed for the first time a systematic analysis of the dissociation and fission pathways of neutral, singly and doubly charged alanine dipeptide ions with the aim to identify the fission mechanism and the most probable fragmentation channels of these type of molecules.
arxiv
Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]
, 2017 Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth +6 more
core +1 more source
Taper-in-Taper Fiber Structure-based LSPR Sensor for Alanine Aminotransferase Detection
Optics Express, 2021 Zhi Wang +5 more
semanticscholar +1 more source
Yonsei medical journal, 2015 Purpose Recent studies have revealed close relationships between hepatic injury, metabolic pathways, and gut microbiota. The microorganisms in the intestine also cause irritable bowel syndrome (IBS).
Seung-Hwa Lee +3 more
semanticscholar +1 more source