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Concentration matters!! ppGpp, from a whispering to a strident alarmone
Molecular Microbiology, 2011SummaryBacteria have developed sophisticated signal transduction pathways to sense and respond to environmental stresses. These pathways include intracellular regulators that elicit adaptive changes in the physiology of the cell. Extensive work, mostly performed in Escherichia coli, showed that the modified nucleotide ppGpp plays a key regulatory role ...
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Alarmone-dependent regulators in Rhizobium etli.
Communications in agricultural and applied biological sciences, 2011info:eu-repo/semantics ...
Vercruysse, M +2 more
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A conserved alarmone as a direct regulator of purine metabolism
Nature Microbiology, 2022openaire +2 more sources
Do stalled replication forks synthesize a specific alarmone?
Journal of Theoretical Biology, 1983Potential causes of premature arrest of a replication fork in vivo include an encounter with a chemical lesion in the DNA, inhibition of one of the essential enzymes of the fork, and spontaneous failure of the fork due to its finite degree of processivity.
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Regulatory Themes and Variations by the Stress-Signaling Nucleotide Alarmones (p)ppGpp in Bacteria
Annual Review of Genetics, 2021Jue D Wang +2 more
exaly
The alarmones (p)ppGpp directly regulate translation initiation during entry into quiescence
Proceedings of the National Academy of Sciences of the United States of America, 2020Kelvin Caban +2 more
exaly
Np 4 A alarmones function in bacteria as precursors to RNA caps
Proceedings of the National Academy of Sciences of the United States of America, 2020Joel Belasco +2 more
exaly

