Results 11 to 20 of about 18,462 (120)

Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. [PDF]

open access: yesPLoS ONE, 2014
Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. No method is currently available for measuring albendazole and its metabolites in silkworm hemolymph.
Li Li   +5 more
doaj   +3 more sources

Comparison of albendazole cytotoxicity in terms of metabolite formation in four model systems

open access: yesJournal of Veterinary Research, 2017
Introduction: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone.
Radko Lidia   +3 more
doaj   +3 more sources

Hapten Synthesis and Monoclonal Antibody Preparation for Simultaneous Detection of Albendazole and Its Metabolites in Animal-Origin Food

open access: yesFoods, 2021
Albendazole (ABZ) is one of the benzimidazole anthelmintics, and the overuse of ABZ in breeding industry can lead to drug resistance and a variety of toxic effects in humans.
Shibei Shao   +8 more
doaj   +2 more sources

LC-MS/MS Analysis of albendazole and its metabolites in animal tissues [PDF]

open access: yesMedicamentul Veterinar, 2010
Treating the animals with veterinary medicines raise the issue of residues that can persist in their edible tissues. In order to establish the withdrawal time necessary for depletion of the residues to sufficiently low concentration not to affect human ...
Ana Csuma,, Ana Cismileanu
doaj   +2 more sources

Impact of Anthelminthic Treatment in Pregnancy and Childhood on Immunisations, Infections and Eczema in Childhood : A Randomised Controlled Trial [PDF]

open access: yes, 2012
Helminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the hypothesis that anthelminthic treatment in pregnancy and early childhood would improve responses to ...
Mpairwe, Harriet   +20 more
core   +5 more sources

Recent Advances in Visible‐Light‐Driven C−S Bond Formation

open access: yesAdvanced Synthesis &Catalysis, Volume 365, Issue 20, Page 3413-3431, October 24, 2023., 2023
Abstract Due their multifaced applications, the access to organosulfur derivatives in an efficient and economical way is a challenge in organic synthesis. In this context photochemistry and photocatalysis play a crucial role in the development of innovative (and selective) Carbon‐Sulphur bond formation processes.
Jiaxu Feng   +7 more
wiley   +1 more source

Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole

open access: yesPLoS Pathogens, 2022
Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ).
Edar O. Pech-Santiago   +7 more
doaj   +2 more sources

Nanocrystal Suspensions for Enhancing the Oral Absorption of Albendazole

open access: yesNanomaterials, 2022
Albendazole (ABZ), an effective benzimidazole antiparasitic drug is limited by its poor solubility and oral bioavailability. In order to overcome its disadvantages, ABZ nanocrystals were prepared using a novel bottom-up method based on acid-base ...
Zhiwei Liang   +4 more
doaj   +1 more source

Effects of triclabendazole and its metabolite exposure on the heart‐rate–corrected QT intervals: A randomized, placebo‐ and positive‐controlled thorough QT study in healthy individuals

open access: yesClinical and Translational Science, Volume 16, Issue 10, Page 1758-1767, October 2023., 2023
Abstract Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of therapeutic (10 mg/kg twice daily [b.i.d.] for 1 day) and supratherapeutic (10 mg/kg b.i.d. for 3 days) oral doses
William T. Prince   +7 more
wiley   +1 more source

Simple method for the determination of anthelmintic drugs in milk intended for human consumption using liquid chromatography–tandem mass spectrometry

open access: yesJournal of the Science of Food and Agriculture, Volume 102, Issue 1, Page 322-329, 15 January 2022., 2022
Abstract BACKGROUND Helminth infections in animals to be consumed by humans are an important medical and public health problem. Pharmaceutical research has focused on developing new anthelmintic drugs for parasite control in these animals. However, the incorrect use of anthelmintics can leave residues in animal products intended for human consumption ...
Myriam Bustamante‐Rangel   +2 more
wiley   +1 more source

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