Results 11 to 20 of about 18,462 (120)
Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. [PDF]
Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. No method is currently available for measuring albendazole and its metabolites in silkworm hemolymph.
Li Li +5 more
doaj +3 more sources
Comparison of albendazole cytotoxicity in terms of metabolite formation in four model systems
Introduction: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone.
Radko Lidia +3 more
doaj +3 more sources
Albendazole (ABZ) is one of the benzimidazole anthelmintics, and the overuse of ABZ in breeding industry can lead to drug resistance and a variety of toxic effects in humans.
Shibei Shao +8 more
doaj +2 more sources
LC-MS/MS Analysis of albendazole and its metabolites in animal tissues [PDF]
Treating the animals with veterinary medicines raise the issue of residues that can persist in their edible tissues. In order to establish the withdrawal time necessary for depletion of the residues to sufficiently low concentration not to affect human ...
Ana Csuma,, Ana Cismileanu
doaj +2 more sources
Impact of Anthelminthic Treatment in Pregnancy and Childhood on Immunisations, Infections and Eczema in Childhood : A Randomised Controlled Trial [PDF]
Helminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the hypothesis that anthelminthic treatment in pregnancy and early childhood would improve responses to ...
Mpairwe, Harriet +20 more
core +5 more sources
Recent Advances in Visible‐Light‐Driven C−S Bond Formation
Abstract Due their multifaced applications, the access to organosulfur derivatives in an efficient and economical way is a challenge in organic synthesis. In this context photochemistry and photocatalysis play a crucial role in the development of innovative (and selective) Carbon‐Sulphur bond formation processes.
Jiaxu Feng +7 more
wiley +1 more source
Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ).
Edar O. Pech-Santiago +7 more
doaj +2 more sources
Nanocrystal Suspensions for Enhancing the Oral Absorption of Albendazole
Albendazole (ABZ), an effective benzimidazole antiparasitic drug is limited by its poor solubility and oral bioavailability. In order to overcome its disadvantages, ABZ nanocrystals were prepared using a novel bottom-up method based on acid-base ...
Zhiwei Liang +4 more
doaj +1 more source
Abstract Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of therapeutic (10 mg/kg twice daily [b.i.d.] for 1 day) and supratherapeutic (10 mg/kg b.i.d. for 3 days) oral doses
William T. Prince +7 more
wiley +1 more source
Abstract BACKGROUND Helminth infections in animals to be consumed by humans are an important medical and public health problem. Pharmaceutical research has focused on developing new anthelmintic drugs for parasite control in these animals. However, the incorrect use of anthelmintics can leave residues in animal products intended for human consumption ...
Myriam Bustamante‐Rangel +2 more
wiley +1 more source

