Results 71 to 80 of about 1,204 (151)

UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus

Frontiers in Physiology, 2020
The nematode Haemonchus contortus, a gastrointestinal parasite of ruminants, can severely burden livestock production. Although anthelmintics are the mainstay in the treatment of haemonchosis, their efficacy diminishes due to drug-resistance development ...
Pavlína Kellerová, Martina Navrátilová, Linh Thuy Nguyen, Diana Dimunová, Lucie Raisová Stuchlíková, Karolína Štěrbová, Lenka Skálová, Petra Matoušková   +7 more
doaj   +1 more source

Differential toxicities of albendazole and its two main metabolites to Balb/c 3T3, HepG2, and FaO lines and rat hepatocytes

Journal of Veterinary Research, 2016
Introduction: The cytotoxicity of anthelmintic agent, albendazole (ABZ) and its two major metabolites, sulfoxide (ABZSO) and sulfone (ABZ-SO2), on non-hepatic Balb/c 3T3 line, two hepatoma cell lines (FaO, HepG2), and isolated rat hepatocytes was ...
Radko Lidia, Minta Maria, Stypuła-Trębas Sylwia   +2 more
doaj   +1 more source

EFFECT OF AIBENDAZOLE ON HUMAN HYDATID CYST: REPORT OF 10 CASES

Journal of Research in Medical Sciences, 2001
Introduction: Operation is the most common treatment for hydatid cysts. However, operation would be useless in some patients with diffuse organ involvement, special anatomic spaces or poor general conditions.
A GHAFOURI, A.A NASR ESFAHANI
doaj  

Depletion of Albendazole and Its Metabolites and Their Impact on the Gut Microbial Community Following Multiple Oral Dosing in Yellow River Carp (Cyprinus carpio haematopterus)

Fishes
Healthy Yellow River carp (Cyprinus carpio haematopterus) reared at a water temperature of 23 ± 0.6 °C were orally administered albendazole (ABZ) at a dose of 12 mg/kg body weight (BW) once daily for seven consecutive days.
Yue Liu, Yan Dai, Yan-Ni Zhang, Wen-Rui Wang, Yu-Xin Chen, Yang-Guang Jin, Long-Ji Sun, Shi-Hao Li, Fang Yang, Xing-Ping Li, Fan Yang   +10 more
doaj   +1 more source

Simultaneous LC-MS/MS Method for the Quantitation of Probenecid, Albendazole, and Its Metabolites in Human Plasma and Dried Blood Spots

Separations
Millions of individuals throughout the world suffer from lymphatic filariasis (LF), which is a morbid disease caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori.
Mamunur Rashid, Yashpal S. Chhonker, Sandeep K. Singh, Daryl J. Murry   +3 more
doaj   +1 more source

Metabolically targeted NIR-II theranostic nanoplatform enabling efficient synergistic phototherapy and chemotherapy for Alveolar echinococcosis

Materials & Design
Alveolar echinococcosis (AE) is a malignant tumor-like parasitic disease whose treatment is limited by poor lesion accessibility and insufficient chemotherapeutic efficacy.
Zenghao Zhao, Bingshuai Zhou, Jun Li, Meiling Wang, Chi Zhang, Jiabao Xiong, Zhong Du, Wenbao Zhang, Biao Dong, Nuernisha Alifu   +9 more
doaj   +1 more source

New benzimidazole derivative compounds with in vitro fasciolicidal properties

Parasites & Vectors
Background Control of the zoonotic food-borne parasite Fasciola hepatica remains a major challenge in humans and livestock. It is estimated that annual economic losses due to fasciolosis can reach US$3.2 billion in agriculture and livestock.
Elora Valderas-García, Verónica Castilla-Gómez de Agüero, Laura González del Palacio, Giulio Galli, Nerea Escala, Marta Ruiz-Somacarrera, Marta González-Warleta, Esther del Olmo, Rafael Balaña-Fouce, María Martínez-Valladares   +9 more
doaj   +1 more source

Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats. [PDF]

BMC Vet Res, 2015
Aksit D, Yalinkilinc HS, Sekkin S, Boyacioğlu M, Cirak VY, Ayaz E, Gokbulut C.   +6 more
europepmc   +1 more source

Post-market surveillance of albendazole tablet brands in Kenya: Implications for deworming programs and clinical outcomes. [PDF]

PLoS Negl Trop Dis
Yator EK, Njogu PM.
europepmc   +1 more source

Biological Safety of Camel Milk After Albendazole and Ivermectin Treatment. [PDF]

Vet Sci
Konuspayeva G, Bilal Z, Akhmetsadykov N, Akhmetsadykova S, Musyaev Z, Amutova F, Kabdullina Z, Utemuratova D, Faye B.   +8 more
europepmc   +1 more source