Results 21 to 30 of about 1,044,683 (223)

Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer [PDF]

Cancer Chemotherapy and Pharmacology, 2019
Gastric cancer (GC) is the third cause of cancer-related death worldwide. Patients with unresectable GC can be treated with chemotherapy such as paclitaxel, which is a microtubule stabilizer. The use of nanoparticle albumin-bound paclitaxel (nab-ptx) avoids hypersensitivity reactions due to the absence of solvent needed to dissolve paclitaxel and it ...
Roviello G., Conter F. U., Mini E., Generali D., Traversini M., Lavacchi D., Nobili S., Sobhani N.   +7 more
openaire   +6 more sources

Development of a Two-Dimensional Liquid Chromatography Online Deproteinization Method for Determining Paclitaxel-Related Substances in a Paclitaxel Injection (Albumin-Bound)

Separations
To determine the paclitaxel-related substances in a paclitaxel injection (albumin-bound), it is necessary to remove human blood albumin from the sample via solid-phase extraction and subsequently perform high-performance liquid chromatography analysis ...
Jing Yao, Xuejia Zhao, Yifei Jiang, Limin Zuo, Xiaodan Qiu, Xiaofang Lian, Huiyi Liu, Qingying Jia, Huimin Sun, Guangzhi Shan   +9 more
doaj   +2 more sources

Albumin-Bound Paclitaxel: The Benefit of This New Formulation in the Treatment of Various Cancers

Journal of Chemotherapy, 2011
Paclitaxel and docetaxel are established as the standards of care, either as monotherapy or in combination with other cytotoxic agents in metastasic breast cancer. In order to improve the efficiency of solvent-based paclitaxel and to overcome its drawbacks in terms of safety, a solvent-free formulation has been developed.
Montana, M., Ducros, C., Verhaeghe, P., Terme, T., Vanelle, P., Rathelot, P.   +5 more
openaire   +4 more sources

First line treatment of advanced non-small-cell lung cancer – specific focus on albumin bound paclitaxel

International Journal of Nanomedicine, 2013
Neha Gupta, Hassan Hatoum, Grace K DyDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USAAbstract: Lung cancer is the leading cause of cancer mortality worldwide in both men and women.
Gupta N, Hatoum H, Dy GK
doaj   +1 more source

Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) as second-line chemotherapy in HER2-negative, taxane-pretreated metastatic breast cancer patients: prospective evaluation of activity, safety, and quality of life

Drug Design, Development and Therapy, 2015
Raffaella Palumbo,1 Federico Sottotetti,1 Giuseppe Trifirò,2 Elena Piazza,3 Antonella Ferzi,4 Anna Gambaro,3 Elena Giulia Spinapolice,2 Emma Pozzi,1 Barbara Tagliaferri,1 Cristina Teragni,1 Antonio Bernardo1 1Departmental Unit of Oncology, IRCCS ...
Palumbo R, Sottotetti F, Trifirò G, Piazza E, Ferzi A, Gambaro A, Spinapolice EG, Pozzi E, Tagliaferri B, Teragni C, Bernardo A   +10 more
doaj   +2 more sources

Efficacy and safety of camrelizumab combined with albumin-bound paclitaxel as third- or later-line regimen in patients with advanced non-small cell lung cancer

Frontiers in Immunology, 2023
BackgroundThe clinical efficacy and safety of camrelizumab as a third- or later-line regimen in patients with advanced non-small cell lung cancer (NSCLC) have not been determined in large clinical trials.ObjectiveThis study aimed to evaluate the clinical
Jianfeng Zhu, Yanyan Yu, Jiaqi Mei, Shiyao Chen, Jiufei Li, Sicong Jiang   +5 more
doaj   +1 more source

Role of Xihuang capsule combined with albumin-bound paclitaxel on the treatment of stage III breast cancer and T cell subsets, survival rate and adverse reactions

Pakistan Journal of Pharmaceutical Sciences, 2023
To investigate the impact of Xihuang Capsule combined with albumin-bound paclitaxel on the treatment of stage III breast cancer and T cell subsets, survival rate and adverse reactions.
Xiaoyu Zhang, Huixin Li, Feng Wu, Dan Sun, Hengle Zhang, Lijun Jin, Xiaoning Kang, Zunyi Wang   +7 more
doaj   +1 more source

Carboplatin plus nanoparticle albumin‑bound paclitaxel for the treatment of thymic carcinoma

Molecular and Clinical Oncology, 2022
Thymic carcinoma is a relatively rare type of malignant tumor. The present retrospective study evaluated the efficacy and safety of carboplatin plus nanoparticle albumin-bound paclitaxel for the treatment of advanced thymic carcinoma. The study included data from 12 patients with advanced thymic carcinoma treated in the Nippon Medical School Hospital ...
Takahashi, Akiko, Noro, Rintaro, Takano, Natsuki, Hisakane, Kakeru, Takahashi, Satoshi, Fukuizumi, Aya, Omori, Miwako, Sugano, Teppei, Takeuchi, Susumu, Nakamichi, Shinji, Miyanaga, Akihiko, Minegishi, Yuji, Kubota, Kaoru, Seike, Masahiro, Gemma, Akihiko   +14 more
openaire   +3 more sources

Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review

Frontiers in Oncology, 2021
Angiographically silent cystoid macular edema (CME) is a rare complication from nab-paclitaxel. Here we report a 45-year-old woman with breast cancer who developed CME after several months of treatment with albumin-bound paclitaxel (nab-paclitaxel).
Suna Ye, Suna Ye, Qiqi Fang, Jinyu Yao, Jianqiang Xing, Shibo Tang, Shibo Tang, Jacey Hongjie Ma, Jacey Hongjie Ma   +8 more
doaj   +1 more source

Cremophor-Induced Lupus Erythematosus-Like Reaction with Taxol Administration: A Case Report and Review of the Literature

Case Reports in Oncology, 2011
We report the first case of Cremophor EL-induced cutaneous lupus erythematosus-like reaction in a 40-year-old female undergoing treatment for breast cancer.
Anthony Q. Pham, David Berz, Patricia Karwan, Gerald A. Colvin   +3 more
doaj   +1 more source