Results 81 to 90 of about 1,044,683 (223)
CellsGlioblastoma remains the most aggressive primary brain malignancy, with poor survival despite maximal safe resection, radiotherapy, and temozolomide-based chemotherapy.
Myung Geun Song, Keon Wook Kang
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Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application
Responsive Materials, EarlyView.Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li +5 more
wiley +1 more source
, 2013 TAILORED NEOADJUVANT EPIRUBICIN AND CYCLOPHOSPHAMIDE AND NANOPARTICLE ALBUMIN BOUND (NAB) PACLITAXEL FOR NEWLY DIAGNOSED BREAST ...
K White (9583325) +13 more
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Responsive Materials, EarlyView.This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang +6 more
wiley +1 more source
Albumin-Bound Paclitaxel in the Treatment of Metastatic Breast Cancer
Clinical Medicine Reviews in Oncology, 2010 The taxanes, paclitaxel and docetaxel, are an important class of antineoplastic agents with relevant clinical activity in both early and advanced breast cancer. Nanoparticle albumin-bound paclitaxel (Abraxane®) is a 130–nm particle cremophor-free formulation of paclitaxel.
openaire +1 more source
Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists
SmartBot, EarlyView.Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu +12 more
wiley +1 more source
Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin [PDF]
, 2019 We describe the design, synthesis, and antitumor activity of an 18 carbon α,ω-dicarboxylic acid monoconjugated via an ester linkage to paclitaxel (PTX). This 1,18-octadecanedioic acid-PTX (ODDA-PTX) prodrug readily forms a noncovalent complex with human ...
Hennis, Robert +15 more
core +2 more sources
Zhongguo aizheng zazhi, 2015 Background and purpose: Pancreatic cancer is often diagnosed at advanced stage, therefore, chemotherapy remains the cornstone of treatment for advanced pancreatic cancer.
彭小波, 颜芳
doaj
Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
Albumin-bound paclitaxel for treatment of patients with refractory metastatic breast cancer
Zhongguo aizheng zazhi, 2014 Background and purpose: Nab-paclitaxel (Abraxane) is an albumin-bound form of paclitaxel that utilizes the natural properties of albumin to improve paclitaxel delivery to the tumor.
梁旭 +8 more
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