Results 41 to 50 of about 1,480,572 (357)

Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy

open access: yesPharmaceutics, 2021
Prodrugs are bioreversible medications that should undergo an enzymatic or chemical transformation in the tumor microenvironment to release active drugs, which improve cancer selectivity to reduce toxicities of anticancer drugs.
Hanhee Cho   +8 more
doaj   +1 more source

PENGARUH PEMBERIAN SUPLEMENTASI SUPEROXIDE DISMUTASE (SOD) TERHADAP KADAR ALBUMIN SERUM PADA LANSIA [PDF]

open access: yes, 2015
Background: Levels of serum albumin can be used as a predictor of morbidity and mortality in the elderly. Reduced serum albumin concentration can be caused by oxidative modification due to aging or insufficient protein intake.
Nalaresi, Andyta   +2 more
core  

Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB. [PDF]

open access: yes, 2018
BackgroundHIV infection and opportunistic infections cause oxidative stress (OS), which is associated with tissue damage. Anti-retroviral therapy (ART) is used to treat HIV and decrease the risk of opportunistic infections, but it is unclear whether ART ...
Andama, Alfred   +14 more
core   +3 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

How Different Albumin-Binders Drive Probe Distribution of Fluorescent RGD Mimetics

open access: yesFrontiers in Chemistry, 2021
The biodistribution of medical imaging probes depends on the chemical nature of the probe and the preferred metabolization and excretion routes. Especially targeted probes, which have to reach a certain (sub)cellular destination, have to be guided to the
Carsten Höltke   +9 more
doaj   +1 more source

Enzyme-linked immunosorbent assay for urinary albumin at low concentrations [PDF]

open access: yes, 1987
We describe an enzyme-linked immunosorbent assay (ELISA) for urinary albumin. It requires only commercially available reagents, can detect as little as 16 micrograms of albumin per liter, and analytical recovery ranges from 92 to 116%.
Jesse, U.   +4 more
core  

A mathematical model for fluid-glucose-albumin transport in peritoneal dialysis

open access: yes, 2013
A mathematical model for fluid and solute transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport with the ...
Cherniha, R.   +2 more
core   +1 more source

Release of macromolecules from albumin-heparin microspheres [PDF]

open access: yes, 1992
Hydrophilic microspheres based on albumin-heparin conjugates have been prepared as a macromolecular delivery system. The soluble albumin-heparin conjugate was synthesized and crosslinked in a water-in-oil emulsion with glutaraldehyde to form microspheres
Bae, You Han   +5 more
core   +2 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Comparison of Clinical Data Between Patients With Complications and Without Complications After Spinal Tuberculosis Surgery: A Propensity Score Matching Analysis

open access: yesFrontiers in Surgery, 2022
PurposeThis study used a propensity score matching (PSM) analysis to explore the risk factors of post-operative complications and compared the differences in clinical data between them following spinal tuberculosis surgery.MethodsThe clinical data of ...
Liyi Chen   +17 more
doaj   +1 more source

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