Results 51 to 60 of about 1,110,362 (306)

Early Albumin Exposure After Cardiac Surgery

, 2021
OBJECTIVES: To determine whether the early use of albumin after cardiac surgery in the first 24 hours in the intensive care unit (ICU) is associated with reduced mortality.
Ramanan, Mahesh, Thang, Christopher, Kumar, Aashish, Marella, Prashanti, Matebele, Mbakise, Christopher Thang, Aashish Kumar, Mbakise Matebele, Prashanti Marella, Mahesh Ramanan   +9 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Efficacy of albumin use in decompensated cirrhosis and real‐world adoption in Australia

JGH Open
The current treatment approach to patients with liver cirrhosis relies on the individual management of complications. Consequently, there is an unmet need for an overall therapeutic strategy for primary and secondary prevention of complications.
Eric Kalo, Scott Read, Asma Baig, Kate Marshall, Wai‐See Ma, Helen Crowther, Cameron Gofton, Kate D Lynch, Siddharth Sood, Jacinta Holmes, John Lubel, Alan Wigg, Geoff McCaughan, Stuart K Roberts, Paolo Caraceni, Golo Ahlenstiel, Avik Majumdar   +16 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF

Frontiers in Medicine
BackgroundIdiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronic inflammation and progressive fibrosis. The blood urea nitrogen-to-albumin ratio (BAR) is a comprehensive parameter associated with inflammation status;
Shaobo Ge, Yuer Li, Rui Li, Jin Liu, Rui Zhang, Hongyan Fu, Jingjing Tang, Jie Zhang, Nali Zhang, Ming Zhang, Ming Zhang   +10 more
doaj   +1 more source

C-Reactive Protein/Albumin Ratio Correlates With Disease Severity and Predicts Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage

Frontiers in Neurology, 2019
Aim: The purpose of the present study was to determine if C-reactive protein (CRP)/albumin ratio was associated with disease severity and unfavorable outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH).Methods: One hundred and twenty-three
Dingding Zhang, Huiying Yan, Yongxiang Wei, Xiangyu Liu, Zong Zhuang, Wei Dai, Jinsong Li, Wei Li, Chunhua Hang   +8 more
doaj   +1 more source

Albumin-Mediated Biomineralization of Shape-Controllable and Biocompatible Ceria Nanomaterials

, 2017
Although ceria-based nanostructures have emerged as fascinating materials with diverse biological activities, developing a facile, rapid, and biocompatible method of their preparation remains a major challenge.
Shenglin Luo (552020), Zhangyou Yang (552019), Yiping Zeng (156254), Rong Li (72042), Chunmeng Shi (2861873)   +4 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Decision-making in wildlife forensics: comparing complex and simple cases at the Wyoming Game and Fish Laboratory

Frontiers in Ecology and Evolution
This study compares the decision-making processes and workflows of complex and simple wildlife forensic cases at the Wyoming Game and Fish Wildlife Forensic Laboratory.
Kimberly M. Frazier, Tasha L. Bauman
doaj   +1 more source

Intracellular delivery of cytochrome c by galactosylated albumin to hepatocarcinoma cells

, 2017
In some cancer cells, translocation of cytochrome c (Cyt c) from mitochondria to the cytoplasma is inhibited. This inhibition prevents cells from undergoing apoptotic cell death and can lead to uncontrolled cell growth.
Yeh, Tzyy-Harn;Wu, Fe-Lin Lin;Shen, Li-Jiuan, 林慧玲;沈麗娟   +1 more
core   +1 more source