Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer [PDF]
, 2001 G.D. Castro +3 more
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Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families [PDF]
, 2001 Aritoshi Iida +9 more
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Cell Proliferation, EarlyView.Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng +10 more
wiley +1 more source
Construction and Screening of Metagenomic Libraries Derived from Enrichment Cultures: Generation of a Gene Bank for Genes Conferring Alcohol Oxidoreductase Activity on Escherichia coli [PDF]
, 2003 Anja Knietsch +4 more
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The FEBS Journal, EarlyView.The authors identify PbfF (previously annotated as a NAD‐dependent dehydrogenase) as a hitherto unknown enzyme in phosphonate catabolism. Guided by genome context analysis, they show that PbfF is actually a racemase, serving to degrade the natural compound (S)‐2‐amino‐1‐hydroxyethylphosphonate (S‐HAEP).
Francesca Ruffolo +8 more
wiley +1 more source
Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?
Internal Medicine Journal, EarlyView.Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman +4 more
wiley +1 more source
Molecular Microbiology, EarlyView.In Hyphomicrobium denitrificans, the use of thiosulfate as a supplemental electron donor is regulated by two homologous sulfane‐sulfur responsive ArsR‐type transcriptional repressors, sHdrR and SoxR, that act cooperatively. Remarkably, the regulation by sHdrR/SoxR extends far beyond sulfur oxidation and deeply affects anaerobic metabolism, particularly
Jingjing Li +3 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.Summary OSW‐1 is a cholestane saponin uniquely produced in Ornithogalum saundersiae and exhibits a potential antitumor activity. The enzymes responsible for OSW‐1 biosynthesis in O. saundersiae, however, remain unclear. Herein, cholesterol was confirmed to be the precursor of OSW‐1 using stable‐isotope labeling method.
Shu‐Yue Zhang, Jian‐Qiang Kong
wiley +1 more source
Metatranscriptome profile of agricultural microbial communities enriched for plastitrophy
mLife, EarlyView.
Fatai A. Olabemiwo +7 more
wiley +1 more source
Physiological Entomology, EarlyView.Biosynthesis of the fatty acid components of the Apis mellifera mandibular gland pheromones takes place in a stepwise manner. Differential gene expression in the mandibular gland tissue of workers from two subspecies of African honey bees with differing reproductive potentials and at two age groups was investigated.
Fiona Nelima Mumoki +3 more
wiley +1 more source