Results 51 to 60 of about 586,881 (303)

Alcohol Use In Mexican-Americans By Nativity: The Role Of Ethnic Identity, Acculturation, And Acculturative Stress [PDF]

open access: yes, 2013
The present study examined alcohol use disorder symptoms among Mexican-Americans. Participants consisted of a community-based sample of 237 Mexican-American adults living in the Midwest United States. The role of nativity status and cultural variables in
Vallejo, Leticia G.
core   +1 more source

Joint versus separate inpatient rehabilitation treatment for patients with alcohol use disorder or drug use disorder : an observational study [PDF]

open access: yes, 2018
Background: In many national treatment systems, patients with alcohol use disorders (AUD) and those with drug use disorders (DUD) are treated separately, while other systems provide joint treatment for both kinds of substance use disorders (SUDs ...
Bender, Stefan   +7 more
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence. [PDF]

open access: yes, 2014
The present paper summarizes the preclinical and clinical studies conducted to define the "anti-alcohol" pharmacological profile of the prototypic GABAB receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD).
Agabio R, Colombo G
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Treatment seeking for alcohol-related issues during the COVID-19 pandemic: An analysis of an addiction-specialized psychiatric treatment facility

open access: yesHeliyon, 2022
The COVID-19 pandemic and its societal impact may cause long-term behavioral changes in alcohol use due to increased psychological distress, unemployment, and time spent home.
Mitchell J. Andersson, Anders Håkansson
doaj  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Trauma exposure and alcohol use disorder among prisoners in Jimma Zone correctional institution, Southwest Ethiopia: a cross-sectional study

open access: yesBMC Research Notes, 2019
Objective Trauma exposure and alcohol use are closely related, and large proportion of trauma-exposed individuals use alcohol. The data presented in this paper were obtained as part of a study on substance use disorder and associated factors among ...
Yimenu Yitayih   +5 more
doaj   +1 more source

Prevalence of major depressive disorder among wives of men with alcohol use disorder-a cross-sectional study from a tertiary care hospital

open access: yesKerala Journal of Psychiatry, 2021
Background: Alcohol Use Disorder is highly prevalent in India. Alcohol acts as a continuous stressor, with several stressfull consequences on the wife.
Vijunath Thilakan   +2 more
doaj   +1 more source

A 10-year Study of Factors Associated with Alcohol Treatment Use and Non-use in a U.S. Population Sample [PDF]

open access: yes, 2016
Background This study seeks to identify changes in perceived barriers to alcohol treatment and predictors of treatment use between 1991–92 and 2001–02, to potentially help understand reported reductions in treatment use at this time.
Caetano, Raul   +3 more
core   +2 more sources

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