Results 41 to 50 of about 135 (134)

Electrochemical Biosensors for Cancer Biomarker Detection: Basic Concept, Design Strategy and Cutting‐Edge Development

Electrochemical Science Advances, EarlyView.
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley   +1 more source

Exploring the bio‐functional potential of polysaccharides from Morchella esculenta: A mini review

Food Biomacromolecules, EarlyView.
Abstract Polysaccharides, natural polymers of monosaccharides, exhibit diverse biological activities due to their molecular structures and functional properties. Morchella esculenta, a precious edible mushroom with higher market value, is also rich in polysaccharides (MEP) and holds potential as a bioactive compound with therapeutic and functional food
Shiva Bakshi, Vinod Kumar Paswan
wiley   +1 more source

Interface and surface engineering of MXenes and COFs for energy storage and conversion

InfoMat, EarlyView.
The work highlights key developments in MXene‐COF integration, advantages/disadvantages, mechanism, and offers insights into their applications in batteries (Li‐ion, K‐ion, Na‐ion, and Li‐S), supercapacitors, and electrocatalysis (HER, OER, RR, NRR, and ORRCO2).
Iftikhar Hussain, Murugavel Kathiresan, Karanpal Singh, B. Kalidasan, Avinash C. Mendhe, Mohammad Nahidul Islam, Kejuan Meng, Muhammad Kashif Aslam, Muhammad Bilal Hanif, Wail Al Zoubi, Kaili Zhang   +10 more
wiley   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

Interdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma, Zhihao Song, Chenlong Yang, Zijin Zhao, Guodong Tang, Jia You, Chong Zeng, Jun Yang, Qing Liu, Haoyu Li, Wei Huang   +10 more
wiley   +1 more source

Toxicological Response of the BEAS‐2B Cell After Acute Exposure at the Air–Liquid Interface to Ethylbenzene and m‐Xylene Alone and in Binary Mixtures

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzene, toluene, ethylbenzene, and xylenes (o‐, m‐, and p‐xylenes) constitute a family, named BTEX, of volatile organic compounds (VOCs) known for its toxicity. This study aimed to study the acute in vitro toxicity of ethylbenzene and m‐xylene on human bronchial epithelial cells exposed at the air–liquid interface (ALI).
Nour Jaber, Claude Emond, Fabrice Cazier, Sylvain Billet   +3 more
wiley   +1 more source

A Transcriptional Variant of Anaplastic Lymphoma Kinase Promotes Apoptosis in Ovarian High‐Grade Serous Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT The current study aims to delineate the role of a novel anaplastic lymphoma kinase (ALK) transcript, ALKATI, in ovarian high‐grade serous carcinoma (HGSC). Overexpressed ALKATI exhibited both cytoplasmic and nuclear localization in HGSC cells, whereas full‐length ALK was predominantly cytoplasmic.
Ako Yokoi, Daigo Yoshimori, Yasuko Oguri, Miki Hashimura, Makoto Saegusa   +4 more
wiley   +1 more source

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen, EarlyView.
Two genetically modified strains are designed and constructed to produce 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) by disrupting and overexpressing the aldolase gene (thl) in the genetically modified strains of Mycolicibacterium neoaurum NRRL B‐3805, respectively, which are useful ...
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
wiley   +1 more source

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

PROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo, Jeremie Zander Lindeque, Marianne Venter   +2 more
wiley   +1 more source

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

PROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre, Jens Hamar, Monica B. Urias, Dietmar Kültz   +3 more
wiley   +1 more source

Intelligent peptide‐based nanomaterials for targeted antibacterial therapy: Design, properties and applications

Responsive Materials, EarlyView.
This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou, Qi Tang, Shuaikang Yang, Guanghui Zhao, Tao Wang, Zhenduo Chen, Yucheng Zhang, Peng Tan, Xi Ma   +8 more
wiley   +1 more source