Results 61 to 70 of about 135 (134)

Mining bioactive components in agricultural crop and food production residue for sustainable solutions: In silico screening for skin anti‐ageing properties

International Journal of Cosmetic Science, EarlyView.
A workflow for identifying sustainable anti‐ageing solutions from agricultural crop and food production residues (ACFPR). A combination of in silico techniques, like database interrogations, target predictions, molecular docking, and ADME predictions can pave the way for the development of innovative, eco‐friendly anti‐ageing cosmetics.
Senka Vidović, Milan Ilić, Jelena Nakomčić, Nataša Nastić, Jelena Kvrgić, Xuanpeng Song, Dimitar Jakimov, Aleksandra Jovanović Galović, Nataša Lješković Jovanović, Mire Zloh   +9 more
wiley   +1 more source

Does the highly prevalent East Asian ALDH2 null variant magnify adverse effects of prenatal alcohol exposure on child development? A commentary

Alcohol, Clinical and Experimental Research, EarlyView.
Chloe Slaney, George Davey Smith
wiley   +1 more source

The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles

Insect Molecular Biology, EarlyView.
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork, Sihang Xu, Athula Attygalle, Tanya Renner   +3 more
wiley   +1 more source

The loss of the urea cycle and ornithine metabolism in different insect orders: An omics approach

Insect Molecular Biology, EarlyView.
Among urea cycle enzymes, only the nitric oxide synthase gene is universally present across insect genomes. All Hemiptera species lack the enzymes needed to convert citrulline to arginine, and some also lack the pathway from arginine to ornithine. Putrescine and spermidine synthesis is conserved in all insects, but aphids lack the capability to produce
Jessica Cristina Silva Martins, Héctor Antônio Assunção Romão, Carolina Kurotusch Canettieri, Amanda Caetano Cercilian, Patrícia Rasteiro Ordiale Oliveira, Clelia Ferreira, Walter R. Terra, Renata de Oliveira Dias   +7 more
wiley   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu, Juyun Zhang, Zhu Lin, Xubiao Meng   +3 more
wiley   +1 more source

Endogenous Ethanol Production in the Human Alimentary Tract: A Literature Review

Journal of Gastroenterology and Hepatology, Volume 40, Issue 4, Page 783-790, April 2025.
ABSTRACT Endogenous ethanol production, or auto‐brewery syndrome (ABS), is a rare condition of the human alimentary canal that results in intoxication without alcohol consumption. Despite its clinical significance, ABS remains largely undiagnosed because of a lack of awareness among clinicians.
Renee Stamation
wiley   +1 more source

Increased Prevalence of Barrett's Esophagus in Taiwan: A Prospective Multicenter Study

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim With rising rates of esophageal adenocarcinoma (EAC) in Western countries, Barrett's esophagus (BE) has become a growing concern. The increasing prevalence of chronic gastroesophageal reflux disease (GERD) in Taiwan suggests a potential rise in BE cases as well.
Fu‐Jen Lee, Ming‐Chang Tsai, Chien‐Lin Chen, Ming‐Wun Wong, Hsu‐Heng Yen, Jeng‐Yih Wu, Chen‐Shuan Chung, Ping‐Huei Tseng, Ying‐Nan Tsai, Ming‐Tsung Hsieh, Chi‐Yang Chang   +10 more
wiley   +1 more source

Embracing the future: Neonatal screening for epileptic syndromes

Epilepsia, EarlyView.
Rima Nabbout, Mathieu Kuchenbuch
wiley   +1 more source

Creation of fragrant peanut using CRISPR/Cas9

Journal of Integrative Plant Biology, EarlyView.
Targeted knockout of the betaine aldehyde dehydrogenase genes AhBADH1 and AhBADH2 using CRISPR/Cas9 produced peanut mutant lines with significantly elevated 2‐acetyl‐1‐pyrroline levels and a strong aroma, marking the first creation of fragrant peanut lines.
Lulu Xue, Pengyu Qu, Huanhuan Zhao, Han Liu, Bingyan Huang, Xiaobo Wang, Zhongxin Zhang, Xiaodong Dai, Li Qin, Wenzhao Dong, Lei Shi, Xinyou Zhang   +11 more
wiley   +1 more source

Cryo‐SEM and large volume FIB‐SEM of Arabidopsis cotyledons: Degradation of lipid bodies, biogenesis of glyoxysomes and reorganisation of organelles during germination

Journal of Microscopy, EarlyView.
Abstract Until recently, the lack of three‐dimensional visualisation of whole cells at the electron microscopic (EM) level has led to a significant gap in our understanding of the interaction of cellular organelles and their interconnection. This is particularly true with regard to the role of the endoplasmic reticulum (ER).
Gerhard Wanner, Elizabeth Schroeder‐Reiter, Farhah F. Assaad   +2 more
wiley   +1 more source