Results 81 to 90 of about 46,498 (194)

Proteomic associations with fluctuation and long‐term changes in BMI: A 40‐year follow‐up study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Introduction While some studies have explored associations between weight change and blood proteins, most have been intervention‐based, offering limited insight into proteomic associations with long‐term weight gain. It remains unclear whether plasma proteins are related to BMI fluctuation over time.
Alvaro Obeso, Gabin Drouard, Teemu Palviainen, Xiaoling Wang, Miina Ollikainen, Karri Silventoinen, Jaakko Kaprio   +6 more
wiley   +1 more source

Mining bioactive components in agricultural crop and food production residue for sustainable solutions: In silico screening for skin anti‐ageing properties

International Journal of Cosmetic Science, EarlyView.
A workflow for identifying sustainable anti‐ageing solutions from agricultural crop and food production residues (ACFPR). A combination of in silico techniques, like database interrogations, target predictions, molecular docking, and ADME predictions can pave the way for the development of innovative, eco‐friendly anti‐ageing cosmetics.
Senka Vidović, Milan Ilić, Jelena Nakomčić, Nataša Nastić, Jelena Kvrgić, Xuanpeng Song, Dimitar Jakimov, Aleksandra Jovanović Galović, Nataša Lješković Jovanović, Mire Zloh   +9 more
wiley   +1 more source

The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles

Insect Molecular Biology, EarlyView.
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork, Sihang Xu, Athula Attygalle, Tanya Renner   +3 more
wiley   +1 more source

The loss of the urea cycle and ornithine metabolism in different insect orders: An omics approach

Insect Molecular Biology, EarlyView.
Among urea cycle enzymes, only the nitric oxide synthase gene is universally present across insect genomes. All Hemiptera species lack the enzymes needed to convert citrulline to arginine, and some also lack the pathway from arginine to ornithine. Putrescine and spermidine synthesis is conserved in all insects, but aphids lack the capability to produce
Jessica Cristina Silva Martins, Héctor Antônio Assunção Romão, Carolina Kurotusch Canettieri, Amanda Caetano Cercilian, Patrícia Rasteiro Ordiale Oliveira, Clelia Ferreira, Walter R. Terra, Renata de Oliveira Dias   +7 more
wiley   +1 more source

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis

New Phytologist, EarlyView.
Summary Sarpagan and akuammiline monoterpenoid indole alkaloids (MIAs) are a class of bioactive plant‐derived compounds with significant pharmaceutical potential. These alkaloids are formed through oxidative cyclization of geissoschizine, catalyzed by homologous cytochrome P450 monooxygenases (CYP) known as sarpagan bridge enzymes (SBEs) and rhazimal ...
Scott Galeung Alexander Mann, Melina Paz‐Galeano, Mohammadamin Shahsavarani, Jacob Owen Perley, Jun Guo, Jorge Jonathan Oswaldo Garza‐Garcia, Yang Qu   +6 more
wiley   +1 more source

Engineering Gypsophila elegans hairy root cultures to produce endosomal escape‐enhancing saponins

Plant Biotechnology Journal, EarlyView.
Summary The limited cytosolic delivery of DNA and protein‐based therapeutics due to endosomal entrapment reduces drug efficacy, increasing treatment costs and possible side effects in human and veterinary medicine as a consequence of higher administered dosages.
Elia Lacchini, Tongtong Qu, Tessa Moses, Alexander N. Volkov, Alain Goossens   +4 more
wiley   +1 more source

Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri.

, 2004
Intracellular symbiosis is very common in the insect world. For the aphid Cinara cedri, we have identified by electron microscopy three symbiotic bacteria that can be characterized by their different sizes, morphologies, and electrodensities.
García-Verdugo, José Manuel, Gómez-Valero, Laura, Heddi, Abdelaziz, Latorre, Amparo, Moya, Andrés, Pérez-Brocal, Vicente, Soriano-Navarro, Mario   +6 more
core   +2 more sources

A Genome‐Wide Association Screen for Genes Affecting Leaf Trichome Development and Epidermal Metal Accumulation in Arabidopsis

Plant, Cell &Environment, Volume 48, Issue 5, Page 3708-3734, May 2025.
ABSTRACT To identify novel genes engaged in plant epidermal development, we characterized the phenotypic variability of rosette leaf epidermis of 310 sequenced Arabidopsis thaliana accessions, focusing on trichome shape and distribution, compositional characteristics of the trichome cell wall, and histologically detectable metal ion distribution.
Radek Bezvoda, Yazmín Mónica Landeo‐Ríos, Zdeňka Kubátová, Eva Kollárová, Ivan Kulich, Wolfgang Busch, Viktor Žárský, Fatima Cvrčková   +7 more
wiley   +1 more source

Dealing with aflatoxin B1 dihydrodiol acute effects: Impact of aflatoxin B1-aldehyde reductase enzyme activity in poultry species tolerant to AFB1 toxic effects. [PDF]

PLoS One, 2020
Murcia H, Diaz GJ.
europepmc   +1 more source