Results 91 to 100 of about 2,516,365 (158)

Differences in Gene Expression between Sonoporation in Tumor and in Muscle

, 2010
Background Ultrasound (US) is a novel and effective tool for the local delivery of genes into target tissues. US can temporarily change the permeability of a cell membrane and thus enhance the delivery of naked DNA into cells.
TSAI, KUN-CHE;LIAO, ZHE-KANG;LIN, WIN-LI;SHIEH, MING-JIUM;HWAN,G LIH-HWA;CHEN, WEN-SHIANG, 蔡坤哲;廖哲康;林文澧;謝銘鈞;黃麗華;陳文翔   +1 more
core   +1 more source

Hypoxia-induced ALDH7A1 expression protects colorectal cancer cells from oxidative stress and DNA damage via a HIF-1-independent mechanism

Tumour hypoxia is associated with increased invasiveness, metastasis, and drug resistance; however, its impact on drug-metabolising enzymes remains poorly understood.
Mark Sutherland, Abdullahi Magaji Dauda, Krishna Khullar, Klaus Pors, Lina Elsalem, Sneha Smarakan, Jan S Moreb, Simon J Allison, Steven D Shnyder, Maria Sadiq, Syed Ali Khurram, Roger M Phillips   +11 more
core   +1 more source

Stria Gravidarum Is Genetic But Not Related With Collagen Gene Polymorphism [PDF]

, 2013
BACKGROUND: Striae Gravidarum (SG) is a common problem that complicates the pregnancies. We aimed to evaluate the possible etiologic factors of SG and the possible importance of collagen polymorphism on SG.
Gungor, Cakir A. N., Gencer, M., Silan, F., Uysal, A., Isik, S., Oguz, S., Uludag, A.   +6 more
core  

Combination Therapy with Pyridoxine and Arginine Supplementations along with a Lysine-Restricted Diet in Individuals with Pyridoxine-Dependent Epilepsy: A Comprehensive Systematic Review

Current Developments in Nutrition
Background: Pyridoxine-dependent epilepsy (PDE) is identified as a rare neurometabolic disease marked by biallelic pathogenic mutations of the ALDH7A1 gene.
Ali Jafari, Mohammad Mehdi Abbasi, Hamid Abbasi, Sama Rahnemayan, Farnush Bakhshimoghaddam, Saeid Doaei   +5 more
doaj   +1 more source

Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1

, 2015
There is growing interest in aldehyde dehydrogenases (ALDHs) because of their overexpression in cancer stem cells and the ability to mediate resistance to cancer drugs.
Kent S. Gates (1310250), Michael T. Henzl (1355046), John J. Tanner (1333191), Min Luo (258201)   +3 more
core   +1 more source

Gene Allen Oral History (part 1)

Gene Allen, Art Director of "My Fair Lady", "A Star is Born", and "Les Girls".

core  

The analyses of C677T and A1298C Polymorphisms on the MTHFR gene and Factor V Leiden mutation in Pseudotumor Cerebri Patients [PDF]

, 2013
Background: In this study, we aimed to investigate the genetic factors which may cause to thrombosis such as C677T and A1298C methylen-thetrahydropholate reductase (MTHFR) gene polymorphisms and Factor V Leiden mutation. Methods: A case-control study was
Aslan, Adem, Erdogan, Mujgan Ozdemir, Yildiz, Handan, Korkmaz, Serhat, Cosar, Murat, Eser, Betul, Eser, Olcay   +6 more
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RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing. [PDF]

, 2013
The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult
Bueno i Torrens, David, 1965-, Hernández Hernández, Victor   +1 more
core  

Gene Allen Oral History (part 2)

Gene Allen, Art Director of "My Fair Lady", "A Star is Born", and "Les Girls".

core  

Neuroimaging Applications for the Delivery and Monitoring of Gene Therapy for Central Nervous System Diseases

Neurological disease due to single gene defects represents a targetable entity for adeno-associated virus (AAV) mediated gene therapy. The delivery of AAV-mediated gene therapy to the brain is challenging, owing to the presence of the blood-brain barrier.
Vardar, Zeynep, Gray-Edwards, Heather L, Daci, Rrita, Flotte, Terence R, Shazeeb, Mohammed Salman, Cataltepe, Oguz I, Vachha, Behroze   +6 more
core   +1 more source