The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]
, 1993 There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet +4 more
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Somatic CACNA1H Mutation As a Cause of Aldosterone-Producing Adenoma
HYPERTENSION, 2020 Supplemental Digital Content is available in the text. Driver somatic mutations for aldosterone excess have been found in ≈90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2)-guided sequencing approach.
K. Nanba +10 more
semanticscholar +1 more source
Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
Kidney Research and Clinical Practice, 2015 Background: Peritoneal fibrosis is one of the major causes of technical failure in patients on peritoneal dialysis. Epithelial-to-mesenchymal transition (EMT) of the peritoneum is an early and reversible mechanism of peritoneal fibrosis. Human peritoneal
Mina Yu +6 more
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Editorial: Adrenal related hypertension: from bench to bedside, volume II. [PDF]
Front Endocrinol (Lausanne)Aminuddin A, Azizan EA.
europepmc +2 more sources
HYPERTENSION, 2020 Primary aldosteronism is an underdiagnosed cause of hypertension. Although inadequate screening is one reason for underdiagnosis, another important contributor is that clinicians may inappropriately exclude the diagnosis when screening aldosterone ...
Nicholas Yozamp +6 more
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Relationship between aldosterone and the metabolic syndrome in patients with obstructive sleep apnea hypopnea syndrome: effect of continuous positive airway pressure treatment. [PDF]
PLoS ONE, 2014 BACKGROUND: Metabolic syndrome (MS) occurs frequently in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). We hypothesized that aldosterone levels are elevated in OSAHS and associated with the presence of MS.
Antonia Barceló +9 more
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The renin‐angiotensin‐aldosterone system and its suppression
Journal of Veterinary Internal Medicine, 2019 Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic kidney disease.
M. Ames, C. Atkins, B. Pitt
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Local aldosterone synthesis in the large intestine of mouse: An incubation study
Journal of International Medical Research, 2022 Objective To investigate the regulation of local aldosterone synthesis by physiological stimulants in the murine gut. Methods Male mice were fed for 14 days with normal, high (1.6%) or low (0.01%) sodium diets.
Zan Pang +3 more
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Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study [PDF]
, 2014 Introduction: Excess aldosterone is associated with increased cardiovascular risk. Aldosterone has a permissive effect on vascular fibrosis. Cardiovascular magnetic resonance imaging (CMR) allows study of vascular function by measuring aortic ...
A McCurley +40 more
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American Journal of Preventive Cardiology, 2023 Background: Greater attainment of ideal cardiovascular health (ICH) and lower serum aldosterone are associated with lower diabetes risk. Higher levels of ICH are associated with lower aldosterone. The mediational role of aldosterone in the association of
Veena Kesireddy +15 more
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