Results 31 to 40 of about 84,187 (148)

Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection.

HYPERTENSION, 2020
Primary aldosteronism is an underdiagnosed cause of hypertension. Although inadequate screening is one reason for underdiagnosis, another important contributor is that clinicians may inappropriately exclude the diagnosis when screening aldosterone ...
Nicholas Yozamp, G. Hundemer, M. Moussa, J. Underhill, T. Fudim, B. Sacks, A. Vaidya   +6 more
semanticscholar   +1 more source

Local aldosterone synthesis in the large intestine of mouse: An incubation study

Journal of International Medical Research, 2022
Objective To investigate the regulation of local aldosterone synthesis by physiological stimulants in the murine gut. Methods Male mice were fed for 14 days with normal, high (1.6%) or low (0.01%) sodium diets.
Zan Pang, Hanna Launonen, Riitta Korpela, Heikki Vapaatalo   +3 more
doaj   +1 more source

The renin‐angiotensin‐aldosterone system and its suppression

Journal of Veterinary Internal Medicine, 2019
Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic kidney disease.
M. Ames, C. Atkins, B. Pitt
semanticscholar   +1 more source

Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure

ESC Heart Failure, 2020
Aims Activation of the renin–angiotensin–aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Masatake Kobayashi, Susan Stienen, Jozine M. terMaaten, Kenneth Dickstein, Nilesh J. Samani, Chim C. Lang, Leong L. Ng, Stefan D. Anker, Macro Metra, Gregoire Preud'homme, Kevin Duarte, Zohra Lamiral, Nicolas Girerd, Patrick Rossignol, Dirk J. vanVeldhuisen, Adriaan A. Voors, Faiez Zannad, João Pedro Ferreira   +17 more
doaj   +1 more source

Twenty-Four-Hour Urinary Aldosterone Predicts Inappropriate Left Ventricular Mass Index in Patients with Primary Aldosteronism

The Scientific World Journal, 2013
Objective. Primary aldosteronism (PA) is associated with inappropriate left ventricular hypertrophy (LVH) in relation to a given gender and body size. There is no ideal parameter to predict the presence of LVH or inappropriate LVH in patients with PA. We
Chi-Sheng Hung, Yi-Lwun Ho, Yi-Yao Chang, Vin-Cent Wu, Xue-Ming Wu, Jen-Kuang Lee, Shih-Chieh Chueh, Yen-Hung Lin, Yuan-Shian Changh, Shao-Yu Yang, Ya-Hui Hu, Ming-Jai Sui, Ming-Fong Chen, Kwan-Dun Wu   +13 more
doaj   +1 more source

The role of aldosterone and ideal cardiovascular health in incident diabetes: The Jackson Heart Study

American Journal of Preventive Cardiology, 2023
Background: Greater attainment of ideal cardiovascular health (ICH) and lower serum aldosterone are associated with lower diabetes risk. Higher levels of ICH are associated with lower aldosterone. The mediational role of aldosterone in the association of
Veena Kesireddy, Bjorn Kluwe, Neal Pohlman, Songzhu Zhao, Yubo Tan, David Kline, Guy Brock, James B. Odei, Valery S. Effoe, Justin B. Echouffo-Tcheugui, Rita R. Kalyani, Mario Sims, Herman A. Taylor, Morgana Mongraw-Chaffin, Ehimare Akhabue, Joshua J. Joseph   +15 more
doaj   +1 more source

Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

HYPERTENSION, 2019
Somatic mutations have been identified in aldosterone-producing adenomas (APAs) in genes that include KCNJ5, ATP1A1, ATP2B3, and CACNA1D. Based on independent studies, there appears to be racial differences in the prevalence of somatic KCNJ5 mutations ...
K. Nanba, K. Omata, C. Gomez-Sanchez, C. Stratakis, A. Demidowich, M. Suzuki, L. Thompson, D. Cohen, J. M. Luther, Lan Gellert, A. Vaidya, J. Barletta, T. Else, T. Giordano, S. Tomlins, W. Rainey   +15 more
semanticscholar   +1 more source

Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4‐Year Follow‐Up

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background We recently reported that normal aldosterone levels are associated with cardiovascular, renal, and metabolic disease in a sample of the US general community (Visit 1).
Alessia Buglioni, Valentina Cannone, S. Jeson Sangaralingham, Denise M. Heublein, Christopher G. Scott, Kent R. Bailey, Richard J. Rodeheffer, Riccardo Sarzani, John C. Burnett Jr   +8 more
doaj   +1 more source

The Effects of Different Calcium Channel Blockers on Aldosterone-Producing Adenoma Cells

Frontiers in Endocrinology, 2020
Purpose: The aim of this study is to examine the effects of different kinds of calcium channel blockers (CCBs) on primary aldosterone-producing adenoma (APA) mainly with KCNJ5 mutations.
Fen Wang, Fen Wang, Xiaosen Ma, Anli Tong, Yushi Zhang, Jin Wen, Yuxiu Li   +6 more
doaj   +1 more source

Aldosterone induces trained immunity: the role of fatty acid synthesis.

Cardiovascular Research, 2019
AIMS Supranormal levels of aldosterone are associated with an increased cardiovascular risk in humans, and with accelerated atherosclerosis in animal models. Atherosclerosis is a low-grade inflammatory disorder, with monocyte-derived macrophages as major
C. V. D. van der Heijden, S. Keating, L. Groh, L. Joosten, M. Netea, N. Riksen   +5 more
semanticscholar   +1 more source