Results 51 to 60 of about 232,884 (341)

Diagnosis and treatment of canine hypoadrenocorticism [PDF]

open access: yes, 2018
Canine hypoadrenocorticism (Addison’s disease), the ‘great pretender’ of internal medicine, is a disease that should be frequently considered as a differential diagnosis of several clinical presentations, albeit it is less commonly the actual cause of ...
Gunn, Eilidh   +2 more
core   +1 more source

Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension

open access: yesInternational Journal of Molecular Sciences, 2016
Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by many factors, including physiological, genetic, and lifestyle causes.
N. Muñoz-Durango   +6 more
semanticscholar   +1 more source

Despite increasing aldosterone, elevated potassium is not necessary for activating aldosterone‐sensitive HSD2 neurons or sodium appetite

open access: yesPhysiological Reports, 2021
Restricting dietary sodium promotes sodium appetite in rats. Prolonged sodium restriction increases plasma potassium (pK), and elevated pK is largely responsible for a concurrent increase in aldosterone, which helps promote sodium appetite.
Frederico S. Fazan   +3 more
doaj   +1 more source

Distal renal tubules are deficient in aggresome formation and autophagy upon aldosterone administration.

open access: yesPLoS ONE, 2014
Prolonged elevations of plasma aldosterone levels are associated with renal pathogenesis. We hypothesized that renal distress could be imposed by an augmented aldosterone-induced protein turnover challenging cellular protein degradation systems of the ...
Muhammad Umar Cheema   +6 more
doaj   +1 more source

The Effect of High Dose Total Body Irradiation on ACTH, Corticosterone, and Catecholamines in the Rat [PDF]

open access: yes, 2011
Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation.
Bruder, Eric D.   +4 more
core   +2 more sources

The Biology of Normal Zona Glomerulosa and Aldosterone-Producing Adenoma: Pathological Implications

open access: yesEndocrine reviews, 2018
The identification of several germline and somatic ion channel mutations in aldosterone-producing adenomas (APAs) and detection of cell clusters that can be responsible for excess aldosterone production, as well as the isolation of autoantibodies ...
T. Seccia   +4 more
semanticscholar   +1 more source

THE GENDER FEATURES OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN HYPERTENSIVE PATIENTS

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study the correlation of the renin-angiotensin-aldosterone system (RAAS) activity with the female sex hormone levels and markers of target organ damage in patients with arterial hypertension (HT).Material and methods. Patients with HT (20 men and
V. I. Podzolkov   +3 more
doaj   +1 more source

Aldosterone and Mineralocorticoid Receptors—Physiology and Pathophysiology

open access: yesInternational Journal of Molecular Sciences, 2017
Aldosterone is a uniquely terrestrial hormone, first appearing in lungfish, which have both gills and lungs. Mineralocorticoid receptors (MRs), on the other hand, evolved much earlier, and are found in cartilaginous and bony fish, presumptive ligand ...
J. Funder
semanticscholar   +1 more source

Possible Underlying Mechanisms Responsible for Aldosterone and Mineralocorticoid Receptor–Dependent Renal Injury

open access: yesJournal of Pharmacological Sciences, 2008
There is increasing evidence indicating the roles of aldosterone and mineralocorticoid receptor (MR) in the pathogenesis of renal injury. In rats, chronic treatment with aldosterone and salt results in severe proteinuria and renal tissue injury ...
Hideyasu Kiyomoto   +3 more
doaj   +1 more source

Activating mutations in CTNNB1 in aldosterone producing adenomas

open access: yesScientific Reports, 2016
Primary aldosteronism (PA) is the most common cause of secondary hypertension with a prevalence of 5–10% in unreferred hypertensive patients. Aldosterone producing adenomas (APAs) constitute a large proportion of PA cases and represent a surgically ...
T. Åkerström   +15 more
semanticscholar   +1 more source

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