Results 51 to 60 of about 96,578 (258)

The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients

Endocrine Regulations, 2020
Objective. The cytochrome 11B2 aldosterone synthase gene (CYP11B2) that links to aldosterone synthase enzyme synthesis changes and blood pressure regulation is of particular interest among the renin-angiotensin-aldosterone system encoding genes.
Sydorchuk Larysa, Dzhuryak Valentina, Sydorchuk Andrii, Levytska Svitlana, Petrynych Volodymyr, Knut Ruslan, Kshanovska Anna, Iftoda Oksana, Tkachuk Olexii, Kyfiak Petro, Popovich Andrii, Khomko Oleh, Sydorchuk Ruslan   +12 more
doaj   +1 more source

BLITZ‐HF: a nationwide initiative to evaluate and improve adherence to acute and chronic heart failure guidelines

European Journal of Heart Failure, Volume 24, Issue 11, Page 2078-2089, November 2022., 2022
Aims To assess adherence to guideline recommendations among a large network of Italian cardiology sites in the management of acute and chronic heart failure (HF) and to evaluate if an ad‐hoc educational intervention can improve their performance on several pharmacological and non‐pharmacological indicators.
Michele Massimo Gulizia, Francesco Orso, Andrea Mortara, Donata Lucci, Nadia Aspromonte, Leonardo De Luca, Giuseppe Di Tano, Giuseppe Leonardi, Alessandro Navazio, Giovanni Pulignano, Furio Colivicchi, Andrea Di Lenarda, Fabrizio Oliva, on behalf of BLITZ‐HF Investigators, G. Pajes, A.R. Felici, P. Midi, G. Leonardi, G. Montana, V. Randazzo, E. Guerri, E. Lo Jacono, V. Zanasi, C. Leuzzi, V. Rizzello, A. Battagliese, N. Pagnoni, G. Pulignano, M. Uguccioni, M.D. Tinti, G.M. Frigo, M. Anselmi, E. Zorzi, I. Battistoni, G.P. Perna, L. Prosseda, M. Pulcini, C. Pellizzari, C. Paolini, G. Bardelli, R. Panciarola, B. Bordoni, S. Urbinati, C. Pedone, C. Greco, E.R. Cosentino, C. Borghi, C. Cuccia, L. Caprini, C. Mariani, C. Borghi, E. Benvenuto, M.B. Zisa, G.M. Francese, M.M. Gulizia, M. Bartolotti, M. Marconi, D. Severini, K. Mboumi, E. Capati, F. Venturi, E. Savini, D. Gabrielli, A. Herbst, F. Orso, F. Sani, C. Minneci, E. Gardini, D. Nanni, C. Lirato, F. Piemonte, P. Ameri, M. Canepa, F. Mainardi, R. Ghinazzi, F. Poletti, C. Inserra, S. Arcidiacono, V. Crisci, C.C. De Carlini, S. Maggiolini, F. Napoli, A.G. Versace, I. Di Matteo, A. Sacco, A.F. Giglio, M.G. Cipriani, G. Mombelli, A. Alberti, V. Antonazzo, O. Agostoni, G. Riboni, G. Guazzotti, S. Mazzetti, A. Mortara, L. Montagna, M.G. Perrelli, L. Scelsi, S. Ghio, A. Gualco, C. Opasich, L. Filippucci, A. Burini, I. Puggia, E. Loiudice, G. Iabichella, A. Nicosia, A. Frisinghelli, G. De Angelis, P. Del Corso, F. Marzo, S. Carigi, G. Piovaccari, S. Refice, T. Nejat, S.A. Di Fusco, F. Colivicchi, D. Pini, P. Romano, G. Padula, A. Gigantino, L. Spera, A. Pagliaro, L.L. Piccioni, C. Napoletano, C. Calcagnile, P. Sbarra, D. Belloli, P.C. Sganzerla, M. Merlo, V. De Paris, M. Driussi, D. Miani, C.A. Gianonatti, L. Moretti, G. Licciardello, V. Palmieri, P. Costa, S. Zingaro, L. Tedesco, A. Iacovoni, M. Liotino, A. Ravera, A. De Castro, G. Rossetti, M. Corda, D. Armata, G. Vianello, E. Pelissero, G. Ruberti, S. D'Orazio, C. Pedrinazzi, D. Robba, A. Carbone, F. De Cian, A. Fucili, F. Grossi, N.D. Brunetti, C. Minoia, M. Pernigo, S. Costa, L. Esposito, G. Senatore, P. Pelaggi, R. Poddighe, E. Zanelli, L. Salvini, G. Galati, A. Zanocco, M. Cannillo, A. Vincenzi, M.A. Losi, L. Caliendo, V. Orrù, E. Carluccio, L. Garritano, E. Garelli, R. Poletti, M. Taglioli, G. Scopelliti, M. Lo Presti, C. Gardini, S. Iosi, C. Tota, M. Mancone, C. De Matteis, F. Rusconi, M.A. Ammirati, G. Cicia, S. Meloni, F. Menozzi, A. Cafro, M. Ribezzo, I. Parrini, S. Giacomelli, G. Russo, F. Morandi, F. Sturniolo   +197 more
wiley   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

Clinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund, Annette Haerdtlein, Wolfgang Fehrmann, Clara Weglage, Tobias Dreischulte, Ulrich Jaehde   +5 more
wiley   +1 more source

Use of guideline‐recommended medical therapy in patients with heart failure and chronic kidney disease: from physician's prescriptions to patient's dispensations, medication adherence and persistence

European Journal of Heart Failure, Volume 24, Issue 11, Page 2185-2195, November 2022., 2022
Patients with heart failure and chronic kidney disease are less likely to receive and persist on guideline‐recommended medical therapies. Aim Half of heart failure (HF) patients have chronic kidney disease (CKD) complicating their pharmacological management.
Roemer J. Janse, Edouard L. Fu, Ulf Dahlström, Lina Benson, Bengt Lindholm, Merel van Diepen, Friedo W. Dekker, Lars H. Lund, Juan‐Jesus Carrero, Gianluigi Savarese   +9 more
wiley   +1 more source

N-terminal domain Increases Activation of Elephant Shark Glucocorticoid and Mineralocorticoid Receptors [PDF]

arXiv, 2019
Cortisol, corticosterone and aldosterone activate full-length glucocorticoid receptor (GR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark GR from the MR.
arxiv  

Right ventricular dysfunction predicts outcome after transcatheter mitral valve repair for primary mitral valve regurgitation

European Journal of Heart Failure, Volume 24, Issue 11, Page 2162-2171, November 2022., 2022
RVD predicts outcome after M‐TEER for PMR. CI, confidence interval; HR, hazard ratio; PMR, primary mitral regurgitation; RVD, right ventricular dysfunction. Abstract Aims Right ventricular dysfunction (RVD), as expressed by right ventricular to pulmonary artery coupling, has recently been identified as a strong outcome predictor in patients undergoing ...
Philipp M. Doldi, Lukas Stolz, Daniel Kalbacher, Benedikt Köll, Martin Geyer, Sebastian Ludwig, Mathias Orban, Daniel Braun, Ludwig T. Weckbach, Thomas J. Stocker, Michael Näbauer, Satoshi Higuchi, Tobias Ruf, Jaqueline Da Rocha e Silva, Mirjam Wild, Noemie Tence, Matthias Unterhuber, Niklas Schofer, Aniela Petrescu, Holger Thiele, Philipp Lurz, Edith Lubos, Stephan von Bardeleben, Nicole Karam, Daryoush Samim, Jean‐Michel Paradis, Christos Iliadis, Erion Xhepa, Christian Hagl, Steffen Massberg, Jörg Hausleiter, on behalf of EuroSMR and PRIME‐MR Investigators, Roman Pfister, Philipp von Stein, Teresa Trenkwalder, Hector Alfonso Alvarez Covarrubias, Sandra Hadjadj, Dounia Rouabhia, Nicolas Brugger, Joanna Bartkowiak   +39 more
wiley   +1 more source

The potential of ACTH in the genesis of primary aldosteronism.

Frontiers in Endocrinology, 2016
Aldosterone is a homeostatic hormone, rising in volume depletion, sodium deficiency and potassium loading, in response to angiotensin11 and elevation of plasma potassium.
John Watson Funder, John Watson Funder
doaj   +1 more source

Transcriptional Activation of Elephant Shark Mineralocorticoid Receptor by Corticosteroids, Progesterone and Spironolactone [PDF]

arXiv, 2018
We report the analysis of activation by corticosteroids and progesterone of full-length mineralocorticoid receptor (MR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Based on their measured activities, aldosterone, cortisol, 11-deoxycorticosterone, corticosterone, 11-deoxcortisol, progesterone and 19 ...
arxiv  

Clinical profile, short and long‐term outcomes of non‐ischaemic cardiogenic shock: A FRENSHOCK sub‐analysis

ESC Heart Failure, EarlyView.
Abstract Aims Although predominant in routine practice, non‐ischaemic cardiogenic shock (NICS) remains underrepresented in past studies, mainly focused on ischaemic cardiogenic shock (CS). This study aims to describe the current NICS picture and define its independent correlates of short‐ and long‐term outcomes.
Miloud Cherbi, François Roubille, Edouard Gerbaud, Eric Bonnefoy, Nicolas Lamblin, Laurent Bonello, Bruno Levy, Pascal Lim, Hamid Merdji, Meyer Elbaz, Hadi Khachab, Jeremy Bourenne, Marie‐France Seronde, Guillaume Schurtz, Brahim Harbaoui, Gerald Vanzetto, Nicolas Combaret, Benoit Lattuca, Guillaume Leurent, Etienne Puymirat, Clément Delmas   +20 more
wiley   +1 more source

Plasma Aldosterone Levels Are Not Associated With Cardiovascular Events Among Patients With High‐Risk Vascular Disease: Insights From the ACCELERATE Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The failure of cholesteryl ester transfer protein inhibitor torcetrapib was associated with an off‐target increase in plasma aldosterone. We sought to evaluate the impact of evacetrapib on plasma aldosterone level and determine the association
Anirudh Kumar, Divyang R. Patel, Danielle M. Brennan, Kathy E. Wolski, A. Michael Lincoff, Giacomo Ruotolo, Ellen McErlean, Govinda Weerakkody, Jeffrey S. Riesmeyer, Stephen J. Nicholls, Steven E. Nissen, Venu Menon   +11 more
doaj   +1 more source