Results 71 to 80 of about 157,760 (344)

Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration

open access: yesRedox Biology, 2017
Aldosterone, with pro-oxidation and pro-autophagy capabilities, plays a key role in liver fibrosis. However, the mechanisms underlying aldosterone-promoted liver sinusoidal endothelial cells (LSECs) defenestration remain unknown.
Xiaoying Luo   +12 more
doaj   +1 more source

Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism

open access: yesFrontiers in Endocrinology, 2016
The major physiological regulators of aldosterone production from the adrenal zona glomerulosa are potassium and angiotensin II; other acute regulators include adrenocorticotropic hormone (ACTH) and serotonin.
Nada El Ghorayeb   +2 more
semanticscholar   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

Hypokalemia and Pendrin Induction by Aldosterone

open access: yesHYPERTENSION, 2017
Aldosterone plays an important role in regulating Na-Cl reabsorption and blood pressure. Epithelial Na+ channel, Na+-Cl− cotransporter, and Cl−/HCO3− exchanger pendrin are the major mediators of Na-Cl transport in the aldosterone-sensitive distal nephron.
Ning Xu   +7 more
semanticscholar   +1 more source

Beyond right or wrong: How partial credit scoring on multiple‐choice questions improves student performance and assessment perceptions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid   +2 more
wiley   +1 more source

The role of aldosterone and ideal cardiovascular health in incident diabetes: The Jackson Heart Study

open access: yesAmerican Journal of Preventive Cardiology, 2023
Background: Greater attainment of ideal cardiovascular health (ICH) and lower serum aldosterone are associated with lower diabetes risk. Higher levels of ICH are associated with lower aldosterone. The mediational role of aldosterone in the association of
Veena Kesireddy   +15 more
doaj  

Aldosterone induces inflammatory cytokines in penile corpus cavernosum by activating the NF-κB pathway

open access: yesAsian Journal of Andrology, 2018
Emerging evidence indicates that aldosterone and mineralocorticoid receptors (MRs) are associated with the pathogenesis of erectile dysfunction. However, the molecular mechanisms remain largely unknown.
Fei Wu   +6 more
doaj   +1 more source

Fifty years of subclinical primary aldosteronism: Importance of early diagnosis [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2012
Clinical presentation of excessive aldosterone secretion is often not specific. The presence of resistant severe hypertension (HT) and signs of hypokalemia is useful but inconsistent characteristic.
Ćirić Jasmina   +2 more
doaj   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome

open access: yesInternational Journal of Hypertension, 2011
Aldosterone facilitates cardiovascular damage by increasing blood pressure and through different mechanisms that are independent of its effects on blood pressure.
P. Stiefel   +3 more
doaj   +1 more source

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