Results 71 to 80 of about 168,526 (308)

Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites [PDF]

, 1993
Torasemide is a new loop diuretic with a longer half-life and longer action than furosemide in healthy subjects. In order to evaluate the pharmacodynamic effects, single oral doses of furosemide (80 mg) and torasemide (20 mg), which were equipotent in ...
Bertheau-Reitha, Ute, Falkner, Christine, Gerbes, Alexander L., Jüngst, Dieter, Paumgartner, Gustav   +4 more
core   +1 more source

Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundDuring high sodium intake, the renin‐angiotensin‐aldosterone system is downregulated and nitric oxide signaling is upregulated in order to remain in sodium balance.
Kelly A. Hyndman, Elena V. Mironova, Jorge F. Giani, Courtney Dugas, Jessika Collins, Alicia A. McDonough, James D. Stockand, Jennifer S. Pollock   +7 more
doaj   +1 more source

Transcriptional Activation of Elephant Shark Mineralocorticoid Receptor by Corticosteroids, Progesterone and Spironolactone [PDF]

arXiv, 2018
We report the analysis of activation by corticosteroids and progesterone of full-length mineralocorticoid receptor (MR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Based on their measured activities, aldosterone, cortisol, 11-deoxycorticosterone, corticosterone, 11-deoxcortisol, progesterone and 19 ...
arxiv  

Short-term heat acclimation is effective and may be enhanced rather than impaired by dehydration [PDF]

, 2014
Most heat acclimation data are from regimes longer than 1 week, and acclimation advice is to prevent dehydration. Objectives: We hypothesized that (i) short-term (5-day) heat acclimation would substantially improve physiological strain and exercise ...
Armstrong, Armstrong, Ashenden, Bergeron, Borg, Brandenberger, Brandenberger, Brengelmann, Buono, Buono, Burge, Casa, Casa, Cheung, Convertino, Convertino, Costill, Cotter, Creasy, Dill, Engell, Epstein, Fellman, Fleming, Fortney, Francesconi, Gabai, Gagge, Garrett, Garrett, Garrett, Gisolfi, Gonzalez-Alonso, Gore, Goulet, Graichen, Greenleaf, Harrison, Harrison, Hopkins, Hopper, Horowitz, Horowitz, Hurwitz, Joyner, Judelson, Kay, Kee-Bum, Kenefick, Lorenzo, Maresh, Marshall, McClung, McConell, Merry, Morris, Moseley, Nadel, Nagashima, Nielsen, Njemini, Noakes, Nose, Oehler, Okazaki, Okazaki, Patterson, Patterson, Patterson, Racinais, Ramanathan, Sawka, Sawka, Sawka, Sawka, Schwimmer, Scoon, Senay, Shido, Shvartz, Strydom, Tetievsky, Turk, Wall, Weller, Witney, Wyndham   +86 more
core   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Obesity, aldosterone excess, and mineralocorticoid receptor activation: Parallel or intersected circumstances?

The Journal of Clinical Hypertension
The obesity pandemic, with its associated comorbidities of hypertension and diabetes, constitutes a global public health issue. Importantly, there is an increasing prevalence of aldosterone excess related to obesity and resultant poor health outcomes ...
Houry Puzantian, Raymond Townsend, Shweta Bansal   +2 more
doaj   +1 more source

Caveolin 1 Modulates Aldosterone‐Mediated Pathways of Glucose and Lipid Homeostasis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundOveractivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in glucose/lipid homeostasis and may modulate MR signaling.
Rene Baudrand, Nidhi Gupta, Amanda E. Garza, Anand Vaidya, Jane A. Leopold, Paul N. Hopkins, Xavier Jeunemaitre, Claudio Ferri, Jose R. Romero, Jonathan Williams, Joseph Loscalzo, Gail K. Adler, Gordon H. Williams, Luminita H. Pojoga   +13 more
doaj   +1 more source

N-terminal domain Increases Activation of Elephant Shark Glucocorticoid and Mineralocorticoid Receptors [PDF]

arXiv, 2019
Cortisol, corticosterone and aldosterone activate full-length glucocorticoid receptor (GR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark GR from the MR.
arxiv  

Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]

, 2018
Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei, He, Wanbing, Huang, Hui, Lin, Ying, Liu, Pinming, Shi, Guangzi, Touyz, Rhian M., Yan, Li, Zhang, Shaoling   +8 more
core   +1 more source

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source