Results 221 to 230 of about 35,946 (260)

The depolymerization of sodium alginate by oxidative degradation

Pharmaceutical Development and Technology, 2011
Alginate has been extensively used as a carrier for macromolecules and as gene delivery vehicle. Both properties are molecular weight (Mw) dependent. Herein, we investigated factors affecting the oxidative depolymerization of alginate. The depolymerization process occurred mainly in the first 1 h.
Shirui, Mao, Tingting, Zhang, Wei, Sun, Xuhong, Ren   +3 more
openaire   +2 more sources

Effect of γ-Irradiation on Degradation of Alginate

Journal of Agricultural and Food Chemistry, 2003
The aqueous solution of alginate was irradiated by 60Co gamma-rays in the dose range of 10-500 kGy. To assess the effect of irradiation on the degradation of alginate, the irradiation-induced changes in the viscosity, molecular weight, color, monomer composition, and sequence were measured.
Lee, Dong Wook, Choi, Won Seok, Byun, Myung Woo, Park, Hyun Jin, Yu, Yong Man, Lee, Chong M.   +5 more
openaire   +3 more sources

Radiation-induced degradation of sodium alginate

Polymer Degradation and Stability, 2000
Abstract Alginates were irradiated as solids or in aqueous solution with Co 60 gamma rays in the dose range of 20 to 500 kGy to investigate the effect of radiation on alginates. Degradation was observed both in the solid state and solution. The degradation in solution was remarkably greater than that in the solid.
Naotsugu Nagasawa, Tamikazu Kume, Fumio Yoshii   +2 more
exaly   +2 more sources

Alginate Sequencing: An Analysis of Block Distribution in Alginates Using Specific Alginate Degrading Enzymes

Biomacromolecules, 2011
Distribution and proportion of β-D-mannuronic and α-L-guluronic acid in alginates are important for understanding the chemical-physical properties of the polymer. The present state of art methods, which is based on NMR, provides a statistical description of alginates.
Olav Andreas Aarstad, Anne Tøndervik, Håvard Sletta, Gudmund Skjåk-Bræk   +3 more
openaire   +2 more sources

Degradable alginate hydrogels crosslinked by the macromolecular crosslinker alginate dialdehyde

Journal of Materials Chemistry, 2012
Alginate dialdehyde (ADA) biopolymers possessing a degree of oxidation of either 10 or 50% (10-ADA and 50-ADA, respectively) were characterized using FTIR, XPS and SEC. The aldehyde vibrational mode at 1740 cm(-1) was observed only in ADA which had been equilibrated under ambient conditions while dry samples did not display this band. Spectral changes,
Jejurikar, Aparna, Seow, Xing Ting, Lawrie, Gwen, Martin, Darren, Jayakrishnan, Athipettah, Grøndahl, Lisbeth   +5 more
openaire   +4 more sources

Viscosity of degradated alginate using cellulase

AIP Conference Proceedings, 2020
Alginate consists of long chain polysaccharides, which has high molecular weight and viscosity. This high viscosity limits its use as a matrix in spray drying encapsulation. Hence, it needs viscosity modification. The viscosity of polysaccharides can be decreased by breaking the large molecule into smaller monomer.
Dyah H. Wardhani, Heri Cahyono, Hana N. Ulya, Aulia Rahmawati, Thio V. K. Sugiarto   +4 more
openaire   +1 more source

Enzymatic degradation of alginate by marine fungi

Hydrobiologia, 1990
A total of 72 pre-selected strains of 19 species of marine fungi were tested for their ability to decompose sodium alginate, calcium alginate or freshly prepared calcium alginate gel. Active alginate decomposition was evident in 18 strains (25% of total tested).
K. Schaumann, G. Weide
openaire   +3 more sources

Isolation of an alginate-degrading organism and purification of its alginate lyase

Journal of Fermentation and Bioengineering, 1991
Abstract We isolated a bacterial strain, OS-ALG-9, which solubilized immobilized gel with calcium alginate in a reactor. It was identified as Pseudomonas sp. We studied the cultural conditions by using a 2.5- l jar fermentor and found that the growth and alginate-degrading enzyme production were optimal at pH 7.0 and 30°C.
Shinichi Kinoshita, Yasushi Kumoi, Atsumi Ohshima, Toshiomi Yoshida, Naoya Kasai   +4 more
openaire   +1 more source

Hydrolytically-degradable click-crosslinked alginate hydrogels

Biomaterials, 2018
Degradable biomaterials aim to recapitulate the dynamic microenvironment that cells are naturally exposed to. By oxidizing the alginate polymer backbone, thereby rendering it susceptible to hydrolysis, and crosslinking it via norbornene-tetrazine click chemistry, we can control rheological, mechanical, and degradation properties of resulting hydrogels.
Lueckgen, A., Garske, D., Ellinghaus, A., Desai, R., Stafford, A., Mooney, D., Duda, G., Cipitria, A. ; https://orcid.org/0000-0002-9918-1512   +7 more
openaire   +3 more sources

Alginate Hydrogels with Tunable Degradation

Macromolecular Rapid Communications
ABSTRACT Hydrogels have found utility as both tissue scaffolds and cell delivery vehicles. As tissue engineering scaffolds, they provide physical and biochemical cues that guide tissue remodeling processes. Degradation of the gel over time is a desirable material property that allows for the complete integration ...
Haoyi Hou, Alison M. Lanzi, Yunpeng Feng, null Raavi, Arturo J. Vegas   +4 more
openaire   +2 more sources