Results 261 to 270 of about 74,825 (303)

Characterization of Multiple Alginate Lyases in a Highly Efficient Alginate-Degrading Vibrio Strain and Its Degradation Strategy

Applied and Environmental Microbiology, 2022
Alginate is an important carbon source in the marine environment, and vibrios are major alginate utilizers. Previous studies focused only on the characteristics of individual alginate lyases in vibrios, but few of them discussed the comprehensive alginate-degrading strategy.
Xinxin He, Yunhui Zhang, Xiaolei Wang, Xiaoyu Zhu, Leiran Chen, Weizhi Liu, Qianqian Lyu, Lingman Ran, Haojin Cheng, Xiao-Hua Zhang   +9 more
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Viscosity of degradated alginate using cellulase

AIP Conference Proceedings, 2020
Alginate consists of long chain polysaccharides, which has high molecular weight and viscosity. This high viscosity limits its use as a matrix in spray drying encapsulation. Hence, it needs viscosity modification. The viscosity of polysaccharides can be decreased by breaking the large molecule into smaller monomer.
Dyah H. Wardhani, Heri Cahyono, Hana N. Ulya, Aulia Rahmawati, Thio V. K. Sugiarto   +4 more
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Hydrolytically-degradable click-crosslinked alginate hydrogels

Biomaterials, 2018
Degradable biomaterials aim to recapitulate the dynamic microenvironment that cells are naturally exposed to. By oxidizing the alginate polymer backbone, thereby rendering it susceptible to hydrolysis, and crosslinking it via norbornene-tetrazine click chemistry, we can control rheological, mechanical, and degradation properties of resulting hydrogels.
Lueckgen, A., Garske, D., Ellinghaus, A., Desai, R., Stafford, A., Mooney, D., Duda, G., Cipitria, A. ; https://orcid.org/0000-0002-9918-1512   +7 more
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Alginate Sequencing: An Analysis of Block Distribution in Alginates Using Specific Alginate Degrading Enzymes

Biomacromolecules, 2011
Distribution and proportion of β-D-mannuronic and α-L-guluronic acid in alginates are important for understanding the chemical-physical properties of the polymer. The present state of art methods, which is based on NMR, provides a statistical description of alginates.
Olav Andreas Aarstad, Anne Tøndervik, Håvard Sletta, Gudmund Skjåk-Bræk   +3 more
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Degradable alginate hydrogels crosslinked by the macromolecular crosslinker alginate dialdehyde

Journal of Materials Chemistry, 2012
Alginate dialdehyde (ADA) biopolymers possessing a degree of oxidation of either 10 or 50% (10-ADA and 50-ADA, respectively) were characterized using FTIR, XPS and SEC. The aldehyde vibrational mode at 1740 cm−1 was observed only in ADA which had been equilibrated under ambient conditions while dry samples did not display this band.
Jejurikar, Aparna, Seow, Xing Ting, Lawrie, Gwen, Martin, Darren, Jayakrishnan, Athipettah, Grøndahl, Lisbeth   +5 more
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Degradable alginate hydrogel microfiber for cell-encapsulation based on alginate lyase loaded nanoparticles

Materials Today Communications, 2021
Abstract Cell-encapsulation in hydrogels is a promising strategy for tissue engineering and cell therapy, particularly alginate hydrogels as they immobilize the cells in porous matrices, which allows an exchange of nutrients and oxygen and protects the cells from immune clearance.
Wisawat Keaswejjareansuk, Somrudee Keawmaloon, Nuttawat Sawangrat, Satit Puttipipatkhachorn, Teerapong Yata, Phornphimon Maitarad, Liyi Shi, Mattaka Khongkow, Katawut Namdee   +8 more
openaire   +1 more source

The depolymerization of sodium alginate by oxidative degradation

Pharmaceutical Development and Technology, 2011
Alginate has been extensively used as a carrier for macromolecules and as gene delivery vehicle. Both properties are molecular weight (Mw) dependent. Herein, we investigated factors affecting the oxidative depolymerization of alginate. The depolymerization process occurred mainly in the first 1 h.
Shirui, Mao, Tingting, Zhang, Wei, Sun, Xuhong, Ren   +3 more
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Encapsulation of fibroblasts causes accelerated alginate hydrogel degradation

Acta Biomaterialia, 2010
Calcium-alginate hydrogel has been widely studied as a material for cell encapsulation for tissue engineering. At present, the effect that cells have on the degradation of alginate hydrogel is largely unknown. We have shown that fibroblasts encapsulated at a density of 7.5 x 10(5) cells ml(-1) in both 2% and 5% w/v alginate remain viable for at least ...
Hunt NC, Smith AM, Gbureck U, Shelton RM, Grover LM   +4 more
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Preparation and potential antitumor activity of alginate oligosaccharides degraded by alginate lyase from Cobetia marina

Carbohydrate Research, 2023
It is of great significance to develop marine resources and study its potential biological activity by using alginate lyase produced by marine psychrophilic bacteria. In the previous study, a new marine psychrophilic bacterium (Cobetia marina HQZ08) was screened from the growth area of Laminaria japonica, and it was found that the strain could ...
Xiao-Ming Qiu, Qi Lin, Bing-De Zheng, Wan-Lin Zhao, Jing Ye, Mei-Tian Xiao   +5 more
openaire   +2 more sources

Modification of alginate degradation properties using orthosilicic acid

Journal of the Mechanical Behavior of Biomedical Materials, 2012
Biopolymers such as alginates have been widely researched for clinical use. Their clinical application, however, have been limited due to their unpredictable and often rapid degradation rates. Here we show that the degradation of an alginate hydrogel can be tailored through the addition of orthosilicic acid (OSA).
Birdi, Gurpreet, Bridson, Rachel H., Smith, Alan M., Mohd. Bohari, Siti Pauliena, Grover, Liam M.   +4 more
openaire   +3 more sources