Results 101 to 110 of about 7,283 (209)

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu   +8 more
wiley   +1 more source

High-Level Expression of a Thermally Stable Alginate Lyase Using Pichia pastoris, Characterization and Application in Producing Brown Alginate Oligosaccharide

open access: yesMarine Drugs, 2018
An alginate lyase encoding gene sagl from Flavobacterium sp. H63 was codon optimized and recombinantly expressed at high level in P.pastoris through high cell-density fermentation.
Haifeng Li   +3 more
doaj   +1 more source

Biochemical characteristics and molecular mechanism of an exo-type alginate lyase VxAly7D and its use for the preparation of unsaturated monosaccharides

open access: yesBiotechnology for Biofuels, 2020
Background As the most abundant polysaccharide in brown algae, alginate has become a promising economical material for bioethanol production. Recently, exo-type alginate lyases have received extensive attention because the unsaturated monosaccharides ...
Luyao Tang   +6 more
doaj   +1 more source

Directional control of angiogenesis to produce a designed multiscale micro-vascular network with bioprinting [PDF]

open access: yes, 2018
Department of Biomedical EngineeringThe biomimetic vascular network is a key element in regeneration of viable, functional and scalable artificial tissues.
Hong, Sung Joon
core  

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors [PDF]

open access: yes, 2008
Biocompatible polymer solutions that can crosslink in situ following injection to form stable hydrogels are of interest as depots for sustained delivery of therapeutic factors or cells, and as scaffolds for regenerative medicine.
Hori, Yuki   +2 more
core   +1 more source

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee   +8 more
wiley   +1 more source

Which microbial factors really are important in Pseudomonas aeruginosa infections? [PDF]

open access: yes, 2015
Over the last two decades, tens of millions of dollars have been invested in understanding virulence in the human pathogen, Pseudomonas aeruginosa. However, the top 'hits' obtained in a recent TnSeq analysis aimed at identifying those genes that are ...
Abdelhamid, Yassmin   +9 more
core   +2 more sources

Genome‐wide association analyses reveal loci controlling 1000‐kernel weight, harvest index, biological yield, and grain yield in bread wheat

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract Understanding the genetic basis of grain yield and related traits in bread wheat under different water regimes is essential for improving moisture stress tolerance and water‐use efficiency. This study aimed to identify stable loci associated with these traits under rainfed conditions.
Sefawdin Berta   +5 more
wiley   +1 more source

Biochemical Characterization of a New Oligoalginate Lyase and Its Biotechnological Application in Laminaria japonica Degradation

open access: yesFrontiers in Microbiology, 2020
Oligoalginate lyases catalyze the degradation of alginate polymers and oligomers into monomers, a prerequisite for biotechnological utilizing alginate.
Shangyong Li   +6 more
doaj   +1 more source

Real‐time quality and safety monitoring of fruit juice using paper‐based platform

open access: yesFood Biomacromolecules, Volume 3, Issue 1, Page 140-162, March 2026.
Schematic illustration of a paper‐based biosensor for rapid detection of fruit juice spoilage. Abstract Food spoilage and safety concerns still remain critically challenging within the fruit juice industry, especially as conventional detection methods, though precise, are often too time‐consuming, costly, and reliant on centralized laboratories.
Priti Das   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy