Results 111 to 120 of about 113,406 (275)

Targeting Metabolic Reprogramming in Tumor: From Mechanisms to Precision Immunotherapies

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Cancer metabolic reprogramming is a key hallmark of tumorigenesis and antitumor immunity. It boosts tumor progression by enhancing cancer cell fitness in hostile microenvironments and facilitates immune evasion by evading natural and therapy‐driven antitumor immune responses.
Tong Zhang, Ping Gao, Linchong Sun
wiley   +1 more source

Isolation and immunocharacterization of lactobacillus salivarius from the intestine of wakame-fed pigs to develop novel "Immunosynbiotics" [PDF]

, 2019
Emerging threats of antimicrobial resistance necessitate the exploration of effective alternatives for healthy livestock growth strategies. ?Immunosynbiotics?, a combination of immunoregulatory probiotics and prebiotics with synergistic effects when used
Albarracín, Leonardo, Aso, Hisashi, Humayun Kober, AKM, Iida, Hikaru, Ikeda-Ohtsubo, Wakako, Islam, M. Aminul, Kitazawa, Haruki, Masumizu, Yuki, Nochi, Tomonori, Suda, Yoshihito, Suzuki, Keiichi, Villena, Julio Cesar, Zhou, Binghui   +12 more
core   +1 more source

Advancing Organ‐on‐Chip Models With a Sacrificial Granular Hydrogel Strategy for Enhanced Permeability and Biomimicry

Small Methods, Volume 9, Issue 12, December 1, 2025.
A reversed granular hydrogel strategy creates highly porous 3D matrices within bone marrow (BM)‐on‐chip devices. Sacrificial alginate microgels generate interconnected microporosity that enhances nano/microparticle and cell mobilitymimicking pathogen agents—from the perfused vascular channel into the BM compartment, while preventing cell sedimentation ...
Hugo R Caires, Óscar Castillo‐Fernández, Núria Sima, Mariana V Magalhães, Andreu Benavent‐Claró, Nil Masó‐Castro, Wanlapa Roobsoong, Carmen Fernandez‐Becerra, Aurora Hernández‐Machado, Hernando A. del Portillo, Cristina C. Barrias   +10 more
wiley   +1 more source

An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation. [PDF]

, 2019
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility.
Deruaz, Maud, Kerr, Matthew D, Mao, Angelo S, Mooney, David J, Raimondo, Theresa M, Scadden, David T, Shah, Nisarg J, Sharda, Azeem, Shih, Ting-Yu, Tager, Andrew M, Vrbanac, Vladimir D, Weaver, James C   +11 more
core   +1 more source

Alginate Lyase and Its Applications in Alginate Oligosaccharides Production

Food Reviews International
In recent years, marine resources become strategic resources and attract widespread attention due to their unique physiological and physiochemical properties. Alginate, a prominent marine polysaccharide, is derived from the cell walls of brown algae and certain bacteria.
Zhang, Wenli, Yang, Junya, Liu, Xiaoyong, Zhu, Yingying, Xu, Wei, Ni, Dawei, Petrova, Penka, Petrov, Kaloyan, Mu, Wanmeng   +8 more
openaire   +1 more source

Genome‐Resolved Approach of Guerrero Negro Hypersaline Microbial Mats Reveals the Metabolic Potential of Key Players in a Stratified Community

Environmental Microbiology, Volume 27, Issue 11, November 2025.
The first metagenome‐assembled genomes (MAGs) from Guerrero Negro hypersaline microbial mats were recovered from natural and incubated samples. These MAGs include dominant and rare taxa, whose metabolic potential provides clues to metabolic versatility in the cycling of three elements (carbon, sulfur, and nitrogen) at the genome and community levels ...
Miguel A. Martínez‐Mercado, Hever Latisnere‐Barragán, Patricia J. Ramírez‐Arenas, Ricardo Vázquez‐Juárez, José Q. García‐Maldonado, Alejandro López‐Cortés   +5 more
wiley   +1 more source

Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]

, 2016
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul, Grumelli, Sandra, Islan, German Abel   +2 more
core   +1 more source

Comparison of the Values of a Novel Exolytic and Two Endolytic Alginate Lyases with Mannuronate Preference for Direct Preparation of Oligosaccharides, Action Modes, and Underlying Catalytic Mechanisms [PDF]

, 2021
Lianghuan Zeng, Junge Li, Yuanyuan Cheng, Dandan Wang, Jingyan Gu, Wenjun Han   +5 more
openalex   +1 more source

Microbial Conversion of Glycerol Into 1,3‐Propanediol by Fermentation: Review of Fundamentals and Operational Strategies

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
This review highlights recent advances in microbial fermentation strategies for converting glycerol, a biodiesel by‐product, into 1,3‐propanediol. It discusses metabolic pathways, microbial inocula and key operational parameters to optimise production, supporting sustainable chemical synthesis aligned with circular economy principles. ABSTRACT Over the
María Fernanda Pérez‐Bernal, Roman Moscoviz, Xiaoli Wang, Nicolas Bernet, Eric Trably   +4 more
wiley   +1 more source

Characterization of a New Bifunctional and Cold-Adapted Polysaccharide Lyase (PL) Family 7 Alginate Lyase from Flavobacterium sp.

Marine Drugs, 2020
Alginate oligosaccharides produced by enzymatic degradation show versatile physiological functions and biological activities. In this study, a new alginate lyase encoding gene alyS02 from Flavobacterium sp. S02 was recombinantly expressed at a high level
Hai-Xiang Zhou, Shan-Shan Xu, Xue-Jing Yin, Feng-Long Wang, Yang Li   +4 more
doaj   +1 more source