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Preparation and potential applications of alginate oligosaccharides

Critical Reviews in Food Science and Nutrition, 2022
Alginate, a linear polymer consisting of β-D-mannuronic acid (M) and α-L-guluronic acid (G) with 1,4-glycosidic linkages and comprising 40% of the dry weight of algae, possesses various applications in the food and nutraceutical industries. However, the potential applications of alginate are restricted in some fields because of its low water solubility
Decheng Bi, Xu Yang, Jun Lu, Xu Xu
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Alginate-Derived Mannuronate Oligosaccharide Attenuates Tauopathy through Enhancing Autophagy

Journal of Agricultural and Food Chemistry, 2021
Polymannuronate (PM) is an acidic polysaccharide prepared from alginate, contained in edible brown seaweeds. An unsaturated mannuronate oligosaccharide (MOS) is an enzymatically depolymerized oligosaccharide prepared from PM. The effects of MOS on attenuating tauopathy were studied in HEK293/Tau cells and primary triple transgenic (3×Tg) neurons.
Decheng Bi   +8 more
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Alginate derived functional oligosaccharides: Recent developments, barriers, and future outlooks

Carbohydrate Polymers, 2021
Alginate is a biopolymer used extensively in the food, pharmaceutical, and chemical industries. Alginate oligosaccharides (AOS) derived from alginate exhibit superior biological activities and therapeutic potential. Alginate lyases with characteristic substrate specificity can facilitate the production of a broad array of AOS with precise structure and
Ushasree, Mrudulakumari Vasudevan   +2 more
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Metabolism and Calcium Antagonism of Sodium Alginate Oligosaccharides

Bioscience, Biotechnology, and Biochemistry, 2007
Sodium alginate oligosaccharides (NaAOs) consisting of a mixture of eight oligosaccharides have previously been reported to lower blood pressure. We investigated in this study the excretion of NaAOs into the urine or feces, and attempted to elucidate the mechanism for lowering blood pressure by using isolated mesenteric arteries from the rabbit.
Takamitsu, Chaki   +4 more
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Alginate Oligosaccharides: Production, Biological Activities, and Potential Applications

Comprehensive Reviews in Food Science and Food Safety, 2019
Abstract Alginate, a group of polyuronic saccharides, has been widely used in both pharmaceutical and food industries due to its unique physicochemical properties as well as beneficial health effects. However, the potential applications of alginate are restricted because of its low water solubility and high ...
Jun Liu   +5 more
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Alginate-chitosan oligosaccharide-ZnO composite hydrogel for accelerating wound healing

Carbohydrate Polymers, 2021
Moist, breathable and antibacterial microenvironment can promote cell proliferation and migration, which is beneficial to wound healing. Here, we fabricated a novel sodium alginate-chitosan oligosaccharide‑zinc oxide (SA-COS-ZnO) composite hydrogel by spontaneous Schiff base reaction, using aldehydated sodium alginate (SA), chitosan oligosaccharide ...
Miao, Zhang   +5 more
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Production of Oligosaccharide from Alginate Using Pseudoalteromonas agarovorans

Applied Biochemistry and Biotechnology, 2009
A marine bacterium was isolated from seawater near the Korean south coast for efficient saccharification from alginate. Based on 16S rDNA sequence, the isolated strain was identified as Pseudoalteromonas agarovorans. Various environmental factors affecting saccharification of alginate using P. agarovorans CHO-12 have been investigated in flask cultures.
DuBok, Choi   +3 more
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Synthesis of Alginate Oligosaccharides Containing L‐Guluronic Acids

Chemistry – An Asian Journal, 2009
AbstractMaking ends meet: The L‐gulopyranosyl trichloroacetimidate and 1,6‐anhydro‐2,3‐di‐O‐benzyl‐β‐L‐gulopyranose, efficiently derived from L‐ascorbic acid, were individually used as a starting unit and an elongation unit to prepare L‐guluronic acid linked alginate oligosaccharides in excellent α selectivity and in good yields.magnified ...
Fa-Chen, Chi   +3 more
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Alginate oligosaccharides enhance small intestine cell integrity and migration ability

Life Sciences, 2020
An integral intestinal barrier is essential for intestinal homeostasis. Yet, as a side effect of cancer treatment, chemotherapeutic drugs have been reported to cause mucositis. In a recent study, we found that alginate oligosaccharides (AOS) prevent busulfan induced intestinal mucositis.
Xiong, B.   +8 more
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Alginate oligosaccharides: Enzymatic preparation and antioxidant property evaluation

Food Chemistry, 2014
Alginate oligosaccharides (AOs) prepared from alginate, by alginate lyase-mediated depolymerization, were structurally characterized by mass spectrometry, infrared spectrometry and thin layer chromatography. Studies of their antioxidant activities revealed that AOs were able to completely (100%) inhibit lipid oxidation in emulsions, superiorly to ...
Mia Falkeborg   +7 more
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