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Alginate Oligosaccharides: Production, Biological Activities, and Potential Applications
Comprehensive Reviews in Food Science and Food Safety, 2019Abstract Alginate, a group of polyuronic saccharides, has been widely used in both pharmaceutical and food industries due to its unique physicochemical properties as well as beneficial health effects. However, the potential applications of alginate are restricted because of its low water solubility and high ...
Jun Liu +5 more
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Critical Reviews in Food Science and Nutrition, 2021
Alginates are linear polymers comprising 40% of the dry weight of algae possess various applications in food and biomedical industries. Alginate oligosaccharides (AOS), a degradation product of alginate, is now gaining much attention for their beneficial role in food, pharmaceutical and agricultural industries.
Chunhua Zhang +7 more
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Alginates are linear polymers comprising 40% of the dry weight of algae possess various applications in food and biomedical industries. Alginate oligosaccharides (AOS), a degradation product of alginate, is now gaining much attention for their beneficial role in food, pharmaceutical and agricultural industries.
Chunhua Zhang +7 more
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Carbohydrate Polymers, 2022
Alginate oligosaccharides (AOS) are degradation products of alginate extracted from brown algae. With low molecular weight, high water solubility, and good biological activity, AOS present anti-inflammatory, antimicrobial, antioxidant, and antitumor properties. They also exert growth-promoting effects in animals and plants.
Shuang, Lu +4 more
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Alginate oligosaccharides (AOS) are degradation products of alginate extracted from brown algae. With low molecular weight, high water solubility, and good biological activity, AOS present anti-inflammatory, antimicrobial, antioxidant, and antitumor properties. They also exert growth-promoting effects in animals and plants.
Shuang, Lu +4 more
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Carbohydrate Research, 2023
It is of great significance to develop marine resources and study its potential biological activity by using alginate lyase produced by marine psychrophilic bacteria. In the previous study, a new marine psychrophilic bacterium (Cobetia marina HQZ08) was screened from the growth area of Laminaria japonica, and it was found that the strain could ...
Xiao-Ming Qiu +5 more
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It is of great significance to develop marine resources and study its potential biological activity by using alginate lyase produced by marine psychrophilic bacteria. In the previous study, a new marine psychrophilic bacterium (Cobetia marina HQZ08) was screened from the growth area of Laminaria japonica, and it was found that the strain could ...
Xiao-Ming Qiu +5 more
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Carbohydrate Research, 2019
This study presents a quick, simple and accurate method to calculate the degree of polymerization (DP) of alginate oligosaccharides (AOS) and low molecular weight alginates from the concentration of reducing sugar determined by 3,5-dinitrosalicylic acid (DNS) assay. 1H NMR spectroscopy, mass spectroscopy (MS) and certified standards were used to verify
Ming, Sun +4 more
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This study presents a quick, simple and accurate method to calculate the degree of polymerization (DP) of alginate oligosaccharides (AOS) and low molecular weight alginates from the concentration of reducing sugar determined by 3,5-dinitrosalicylic acid (DNS) assay. 1H NMR spectroscopy, mass spectroscopy (MS) and certified standards were used to verify
Ming, Sun +4 more
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Food Chemistry
To achieve the cost-effective alginate oligosaccharides production, we have developed a novel rational design strategy that optimized capture behavior, orientation movement and hydrogen bond interaction of substrate in alginate lyase ALYI1. This approach led to S56D and G258Q advantageous variants balancing the trade-off challenge, particularly S56D ...
Jin-Ping, Huang +9 more
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To achieve the cost-effective alginate oligosaccharides production, we have developed a novel rational design strategy that optimized capture behavior, orientation movement and hydrogen bond interaction of substrate in alginate lyase ALYI1. This approach led to S56D and G258Q advantageous variants balancing the trade-off challenge, particularly S56D ...
Jin-Ping, Huang +9 more
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Design, synthesis and biological evaluation of alginate oligosaccharide derivatives
Bioorganic & Medicinal Chemistry LettersTo discover new potential drug for acute kidney injury (AKI), a series of novel alginate oligosaccharide derivatives were synthesized and characterized by the spectroscopic analysis. By using the controlled experimental method, the target compounds were evaluated preliminarily for therapeutic activity in AKI. The results demonstrated that compounds 2a,
Wenkang Guo +5 more
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Nutrition Research, 2006
Abstract To investigate the prebiotic potential of alginate oligosaccharides (AOS), prepared through enzymatic hydrolysis of alginate polymer, the effects of AOS on bacterial growth were studied. In vitro studies showed that the numbers of bifidobacteria or lactobacilli were greater than those in control medium when they were cultured in the medium ...
Ye Wang +4 more
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Abstract To investigate the prebiotic potential of alginate oligosaccharides (AOS), prepared through enzymatic hydrolysis of alginate polymer, the effects of AOS on bacterial growth were studied. In vitro studies showed that the numbers of bifidobacteria or lactobacilli were greater than those in control medium when they were cultured in the medium ...
Ye Wang +4 more
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Alginate oligosaccharides: Enzymatic preparation and antioxidant property evaluation
Food Chemistry, 2014Alginate oligosaccharides (AOs) prepared from alginate, by alginate lyase-mediated depolymerization, were structurally characterized by mass spectrometry, infrared spectrometry and thin layer chromatography. Studies of their antioxidant activities revealed that AOs were able to completely (100%) inhibit lipid oxidation in emulsions, superiorly to ...
Mia Falkeborg +7 more
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International Journal of Biological Macromolecules
Alginate is mainly a linear polysaccharide composed of randomly arranged β-D-mannuronic acid and α-L-guluronic acid linked by α, β-(1,4)-glycosidic bonds. Alginate lyases degrade alginate mainly adopting a β-elimination mechanism, breaking the glycosidic bonds between the monomers and forming a double bond between the C4 and C5 sugar rings to produce ...
Chen, Chen +7 more
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Alginate is mainly a linear polysaccharide composed of randomly arranged β-D-mannuronic acid and α-L-guluronic acid linked by α, β-(1,4)-glycosidic bonds. Alginate lyases degrade alginate mainly adopting a β-elimination mechanism, breaking the glycosidic bonds between the monomers and forming a double bond between the C4 and C5 sugar rings to produce ...
Chen, Chen +7 more
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