Results 91 to 100 of about 945,769 (248)

Overview of Radar Alignment Methods and Analysis of Radar Misalignment’s Impact on Active Safety and Autonomous Systems

Sensors
The rapid development of active safety systems in the automotive industry and research in autonomous driving requires reliable, high-precision sensors that provide rich information about the surrounding environment and the behaviour of other road users ...
Rafał Michał Burza
doaj   +1 more source

Verb Phrases Alignment Technique for English-Malayalam Parallel Corpus in Statistical Machine Translation Special issue on MTIL 2017

Journal of Intelligent Systems, 2019
Machine translation (MT) from English to foreign languages is a fast developing area of research, and various techniques of translation are discussed in the literature. However, translation from English to Malayalam, a Dravidian language, is still in the
Sebastian Mary Priya, Kumar G. Santhosh
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Influence of different standing positions on anatomical parameters of coronal whole‐leg weight‐bearing radiographs in preoperative planning for high tibial osteotomy

Journal of Experimental Orthopaedics
Purpose The purpose of this study was to assess the differences in lower limb global alignment and anatomical parameters of coronal whole‐leg radiographs, which were generally used in preoperative planning for high tibial osteotomy (HTO), according to ...
Tomoaki Kamiya, Kodai Hamaoka, Akira Ono, Yohei Okada, Makoto Emori, Atsushi Teramoto   +5 more
doaj   +1 more source

Alignment charts

, 1944
Contents [start-list] *A. Introduction *B. Scales *C. Slide Rules *D. Three-rowed Determinants *E. Alignment Charts *F. The Quadratic and the Reduced Cubic *G. Parallel Scales *H. Mechanical Details *I. The Transformation Theory *J. Projective Transformations *K. The Straight Line *L. Conics *M. The Problem of the Rectangular Page *N.
openaire   +3 more sources

Aligners: Decoupling LLMs and Alignment

Findings of the Association for Computational Linguistics: EMNLP 2024
Large Language Models (LLMs) need to be aligned with human expectations to ensure their safety and utility in most applications. Alignment is challenging, costly, and needs to be repeated for every LLM and alignment criterion. We propose to decouple LLMs and alignment by training aligner models that can be used to align any LLM for a given criteria on ...
Ngweta, Lilian, Agarwal, Mayank, Maity, Subha, Gittens, Alex, Sun, Yuekai, Yurochkin, Mikhail   +5 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source