Results 41 to 50 of about 614 (192)

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

Allergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang, Telly Sepahpour, Stephanie Kortchak, Kirthiram Krishnaveni Sivakumar, Spyros Karaiskos, Ngoc Pham, Yura Jang, Montserrat Puig, Michael Norcross   +8 more
wiley   +1 more source

Nutritional characterization of Cusco green tea and its synergistic effect with omega‐3 on metabolic and cognitive dysfunctions in obese rats

Journal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5643-5657, July 2026.
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova, Nataly Bernuy‐Osorio, Miguel Rodriguez‐Pozo, Aya Maaloul, Roberto T Abdala‐Diaz, Juan Decara   +5 more
wiley   +1 more source

Antioxidants in Plant‐Based Food Matrices: From Structure–Activity and Degradation Kinetics to Formulation Design

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella, Carmen Silvia Favaro‐Trindade, Bárbara Miranda‐Vilela, Mariana Estefanuto‐Costa, Marina Franco‐Brito, Bibiana Alves dos Santos, Paulo Cezar Bastianello Campagnol   +6 more
wiley   +1 more source

Frei Agostinho da Cruz: a «via plana e clara»

Lusitania Sacra, 2022
Frei Agostinho da Cruz cultivou a poesia ao divino, em voga na segunda metade do século XVI. Estreitamente relacionada com a tratadística espiritual concebida até no meio arrábido, a sua poesia espelha um processo de conversão que, sem depreciar em ...
Isabel Almeida
doaj   +1 more source

In Vitro Biological Activities of Piper corcovadensis C.DC.: Antioxidant, Antineoplastic‐Related and Antibacterial Effects

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Piper corcovadensis extract is rich in bioactive compounds with antioxidant potential, capable of decreasing ROS levels; antitumor activity in cutaneous melanoma cells SK‐MEL‐28; and anti‐inflammatory activity, decreasing the expression of IL‐6 and NLPR3 genes and increasing TNF expression, without cytotoxicity to healthy peripheral blood cells (PBMCs).
Bruno Henrique Fontoura, Ellen Cristina Perin, Margarete Dulce Bagatini, Daiane Manica, Gilnei Bruno da Silva, Michelle Fernanda Faita Rodrigues, José Abramo Marchese, Solange Teresinha Carpes   +7 more
wiley   +1 more source

Dieta Natural (BARF) vs. Dieta Comercial (CROQUETAS)

Revista de Veterinaria y Zootecnia Amazónica, 2022
El presente trabajo se realizó con el objetivo de evaluar la relación costo beneficio de una dieta natural (BARF) y una dieta una dieta comercial (CROQUETAS) en perros criollo, en la ciudad de Tarapoto. Se trabajó con un total de 16 canes, de los cuales
Julio Terán-Piña, Jury Chong Insapillo, Zulema Rojas-Vasquez, Felipe Gutiérrez-Arce, Roberto Roque-Alcarraz   +4 more
doaj   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1650-1661, June 2026.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Effect of Cell Disruption and Protein Extraction on the Structural and Technological Properties of Tetradesmus obliquus Protein‐Rich Extracts

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
Despite its considerable potential as a functional food ingredient, T. obliquus faces a major limitation in protein recovery due to the rigidity of its cell wall. In the microalgae industry, protein extraction typically involves two main steps: cell disruption and protein extraction.
César Augusto Sodré da Silva, Tamires Souza Silva, Nayara Flores Fonseca, Rejane de Castro Santana, Jose Roberto Miranda Júnior, Márcio Arêdes Martins, Jane Sélia dos Reis Coimbra   +6 more
wiley   +1 more source

Cultivo de las microalgas dulceacuícolas Kirchneriella obesa, Scenedesmus quadricauda y Chlorococcum infusorium empleando tres medios de cultivo

AIA Avances en Investigación Agropecuaria, 2012
Se cultivaron las microalgas dulceacuícolas Kirchneriella obesa (G. S. West) Schmidle 1893, Scenedesmus quadricauda (Chodat, Turpin) Bréb 1835 y Chlorococcum infusorium (Schrank) Meneghini 1842, con el propósito comparar las tasas de crecimiento y su ...
A. A. Ortega-Salas, H. Reyes-Bustamante
doaj  

Potential Effects of Prepubertal Exposure to Perfluorooctane Sulfonic Acid on the First Wave of Folliculogenesis in Young CD‐1 Mice

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Perfluorooctane sulfonic acid (PFOS) belongs to a group of synthetic chemicals referred to as per‐ and polyfluoroalkyl substances (PFAS) that are known to degrade slowly. Exposure to PFOS has been reported to cause birth defects and disrupt female sex hormone levels in mice.
Bounleut Phanavanh, Jalina Moore, Amy Inselman, Xiaoqing Li, Kyung Sung, Pei‐Hsuan Hung, Li You, Noriko Nakamura   +7 more
wiley   +1 more source