Results 51 to 60 of about 193,702 (280)
Praca na własny rachunek a ochrona w zakresie zbiorowego prawa pracy
W wyniku nowelizacji ustawy o związkach zawodowych, która weszła w życie 1 stycznia 2019 r., osoby świadczące pracę na własny rachunek spełniające kryteria wskazane w art. 11 pkt 1 ustawy o związkach zawodowych zostały wyposażone w szersze prawo koalicji
Monika Latos-Miłkowska
doaj +1 more source
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
A Case of Metastatic Atypical Neuroendocrine Tumor with ALK Translocation and Diffuse Brain Metastases. [PDF]
A challenge in precision medicine requires identification of actionable driver mutations. Critical to such effort is the deployment of sensitive and well-validated assays for mutation detection.
Ali, Siraj +9 more
core +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Global variations of IgE cross-reactivity in Cupressus allergy
Background: Seasonal allergic rhinitis triggered by Cupressaceae species is a significant concern worldwide, particularly in regions such as Japan, China, Spain, and the United States.
Takeru Sugawara, MSc +12 more
doaj +1 more source
Ceritinib in the treatment of ALK-positive patients with nonsmall-cell lung cancer
Ceritinib is the second ALK tyrosine kinase inhibitor after crizotinib, registered in the Russian Federation for the treatment of ALKpositive patients with non-small cell lung cancer (NSCLC). Later alectinib was registered. Thus, we have the opportunity,
K. K. Laktionov, E. V. Reutova
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Opportunities and challenges of circulating biomarkers in neuroblastoma [PDF]
Molecular analysis of nucleic acid and protein biomarkers is becoming increasingly common in paediatric oncology for diagnosis, risk stratification and molecularly targeted therapeutics. However, many current and emerging biomarkers are based on analysis
Ricky M. Trigg +2 more
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BackgroundRespiratory allergy, commonly manifesting as allergic rhinitis (AR) and asthma, is a chronic progressive disease that frequently starts in childhood.
Benedikt Fritszching +5 more
doaj +1 more source
Effect of fibre treatments on interfacial shear strength of hemp fibre reinforced polylactide and unsaturated polyester composites [PDF]
Surface treatment of hemp fibres was investigated as a means of improving interfacial shear strength (IFSS) of hemp fibre reinforced polylactide (PLA) and unsaturated polyester (UPE) composites. Fibres were treated with sodium hydroxide, acetic anhydride,
Fernyhough, Alan +2 more
core +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source

