Eco-friendly RP-HPLC method for determination of diazepam in coated tablet
A new eco-friendly RP-HPLC method for determining diazepam in coated tablets was developed and validated. The separation was achieved on a Lichrosper® 100 RP-18 (250 mm × 4 mm, 5 µm particle size) using the isocratic elution mode with a mobile phase ...
Marija Tomić +6 more
doaj +1 more source
Fast and simple closed-vessel microwave-assisted digestion procedure was developed for decomposition of three pharmaceutical dosage forms of ibuprofen such as tablets, suspension and gel, prior to elemental impurity analysis by one robust and precise ...
Katerina Jancevska +4 more
doaj +1 more source
Providing clinical evidence under the MDR 2017/745: New challenges for manufacturers in medical device industry [PDF]
Providing necessary clinical evidence throughout the systems for Clinical Evaluation and Post-Market Surveillance in accordance with new MDR 2017/745 requirements imposes new challenges for manufacturers in medical device industry.
Ivanovska Elena +5 more
doaj +1 more source
This research highlights the specificity of the new stability-indicating method developed to evaluate the impurity profile of Atorvastatin film-coated tablets. The proposed method has the ability to capture any possible changes that may occur during the
Elena Trajchova Kovachovska +6 more
doaj +1 more source
Investigation of the influence of critical process parameters in roller compaction process on physical properties of granules and tablets using design of experiments [PDF]
Different granulation methods are used in the pharmaceutical industry, mainly divided as wet or dry granulation. Although roller compaction is a widely used dry granulation process, the evaluation of critical process parameters has proven challenging ...
Atanaskova Elizabeta +2 more
doaj +1 more source
Poison Frog Colors Are Honest Signals Of Toxicity, Particularly For Bird Predators [PDF]
Antipredator defenses and warning signals typically evolve in concert. However, the extensive variation across taxa in both these components of predator deterrence and the relationship between them are poorly understood.
Cummings, Molly E., Maan, Martine E.
core +7 more sources
A study of The effect of the aqueous extract of different organs of Peganum harmala L. on the germination and growth of Amaranthus retroflexus L. and Chenopodium album L. [PDF]
This research was conducted in order to investigate the effect of aqueous extract of different organs of harmel (Peganum harmala) on the growth and germination of Amaranthus retroflexus and Chenopodium album in two experiments (laboratory and greenhouse)
Reza Rezvani, Alireza Dadkhah
doaj +1 more source
Structure-activity relationships of synthetic analogs of jasmonic acid and coronatine on induction of benzo[c]phenanthridine alkaloid accumulation in Eschscholzia californica cell cultures [PDF]
A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like ...
Dzink J.L. +5 more
core +1 more source
Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]
Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain +11 more
core +4 more sources
How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]
The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
core +4 more sources

