Results 91 to 100 of about 225,386 (346)

α‐Amination of 1,3‐Dicarbonyl Compounds and Analogous Reactive Enolate‐Precursors Using Ammonia under Oxidative Conditions

open access: yesAngewandte Chemie International Edition, EarlyView.
Using ammonia in combination with hypochlorites as simple oxidants under phase‐transfer conditions allows for the direct oxidative α‐amination of reactive enolate precursors such as cyclic β‐ketoesters, oxindoles, as well as malonitriles and malonates with good to excellent yields.
Christopher Mairhofer   +6 more
wiley   +1 more source

AVANÇOS RECENTES NA HIDROAMINAÇÃO DE COMPOSTOS INSATURADOS

open access: yesQuímica Nova
This review presents thermodynamics and kinetics aspects of the hydroamination reaction, recent advancements on this field for non-activated alkenes, alkynes and allenes, employing transition metal catalysis or organocatalysis, including activation by ...
Luiz F. T. Novaes, Julio C. Pastre
doaj   +1 more source

(−)-Kunstleramide, a New Antioxidant and Cytotoxic Dienamide from the Bark of Beilschmiedia kunstleri Gamble

open access: yesMolecules, 2012
A new dienamide, (2E,4E)-7-(3',4'-dimethoxyphenyl)-N-ethyl-6-(R)-hydroxyhepta- 2,4-dienamide, named (-)-kunstleramide (1), were isolated from the bark of Beilschmiedia kunstleri Gamble together with one neolignan: (+)-kunstlerone (2) and seven known ...
A. Hamid A. Hadi   +2 more
doaj   +1 more source

Molecular and cellular paradigms of multidrug resistance in cancer

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya   +6 more
wiley   +1 more source

Hazards to golden-mantled ground squirrels and associated secondary hazard potential from strychnine baiting for forest pocket gophers [PDF]

open access: yes, 1984
Radio telemetry and capture-recapture techniques were used to evaluate the hazards to golden-mantled ground squirrels (Spermophilus lateralis) from hand baiting with 0.5% strychnine-treated oats for western pocket gophers (Thomomys mazama) on conifer ...
Anthony, R. Michael   +2 more
core  

Alternative final steps in berberine biosynthesis in Coptis japonica cell cultures [PDF]

open access: yes, 1988
In Coptis japonica cell cultures an alternative pathway has been discovered which leads from (S)-tetrahydrocolumbamine via (S)-canadine to berberine. The two enzymes involved have been partially purified.
Galneder, E.   +4 more
core   +1 more source

A Journey Under the Sea: The Quest for Marine Anti-Cancer Alkaloids

open access: yesMolecules, 2011
The alarming increase in the global cancer death toll has fueled the quest for new effective anti-tumor drugs thorough biological screening of both terrestrial and marine organisms.
Nadine Darwiche   +2 more
doaj   +1 more source

Determination of pyrrolizidine alkaloids in dietary sources using a spectrophotometric method [PDF]

open access: yes, 2018
Pyrrolizidine alkaloids (PAs) are a class of toxic compounds found in the composition of more than 6000 plants. People can be exposed to PAs by consuming phytotherapeutic products, food from crops contaminated with seeds of some species with high content
Diaconu, Camelia   +10 more
core   +1 more source

Handbook of Organic Food Safety and Quality [PDF]

open access: yes, 2007
Handbook of organic food safety and quality - Improve the safety, quality and health benefits of organic foods - Discusses the latest research findings in this area - Focuses on assuring quality and safety throughout the food chain - Quality ...

core   +1 more source

Cephalotaxus Alkaloids

open access: yes, 2017
Cephalotaxus alkaloids represent a family of plant secondary metabolites known for 60 years. Significant activity against leukemia in mice was demonstrated for extracts of Cephalotaxus. Cephalotaxine (CET) (1), the major alkaloid of this series was isolated from Cephalotaxus drupacea species by Paudler in 1963.
Pérard-Viret, Joelle   +4 more
openaire   +5 more sources

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