Results 101 to 110 of about 390,408 (384)
The Potential of Tetrandrine as a Protective Agent for Ischemic Stroke
Molecules, 2011 Stroke is one of the leading causes of mortality, with a high incidence of severe morbidity in survivors. The treatment to minimize tissue injury after stroke is still unsatisfactory and it is mandatory to develop effective treatment strategies for ...
Sheng-Hong Tseng, Ya-Hui Tsai, Yun Chen
doaj +1 more source
Toxins, 2013 Ergot alkaloids are pharmaceutically and agriculturally important secondary metabolites produced by several species of fungi. Ergot alkaloid pathways vary among different fungal lineages, but the pathway intermediate chanoclavine-I is evolutionarily ...
Katy L. Ryan +2 more
semanticscholar +1 more source
AVANÇOS RECENTES NA HIDROAMINAÇÃO DE COMPOSTOS INSATURADOS
Química NovaThis review presents thermodynamics and kinetics aspects of the hydroamination reaction, recent advancements on this field for non-activated alkenes, alkynes and allenes, employing transition metal catalysis or organocatalysis, including activation by ...
Luiz F. T. Novaes, Julio C. Pastre
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Molecules, 2012 A new dienamide, (2E,4E)-7-(3',4'-dimethoxyphenyl)-N-ethyl-6-(R)-hydroxyhepta- 2,4-dienamide, named (-)-kunstleramide (1), were isolated from the bark of Beilschmiedia kunstleri Gamble together with one neolignan: (+)-kunstlerone (2) and seven known ...
A. Hamid A. Hadi +2 more
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Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
, 2013 Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Dörnyei, Gábor +5 more
core +1 more source
A Journey Under the Sea: The Quest for Marine Anti-Cancer Alkaloids
Molecules, 2011 The alarming increase in the global cancer death toll has fueled the quest for new effective anti-tumor drugs thorough biological screening of both terrestrial and marine organisms.
Nadine Darwiche +2 more
doaj +1 more source
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
Journal of Clinical Endocrinology and Metabolism, 2008 CONTEXT Berberine, a natural plant alkaloid, is usually used as an antibiotic drug. The potential glucose-lowering effect of berberine was noted when it was used for diarrhea in diabetic patients. In vitro and in vivo studies have then showed its effects
Yifei Zhang +11 more
semanticscholar +1 more source
The Chemistry and Biology of the Tetrodotoxin Natural Product Family
Angewandte Chemie International Edition, Accepted Article.Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation in 1964, it has attracted the interest of synthetic organic chemists due to its exceptional polarity, complex architecture, and important biological activity.
Benedikt Nißl +6 more
wiley +1 more source
Columbamine, the central intermediate in the late stages of protoberberine biosynthesis [PDF]
, 1986 A specific methyltransferase which in the presence of S-adenosylmethionine [SAM] converts columbamine to palmatine has been demonstrated to occur in cell cultures.
Rüffer, Martina, Zenk, Meinhart H.
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The Plant Journal, 2011 Jasmonates are plant signalling molecules that play key roles in defence against insects and certain pathogens, among others by controlling the biosynthesis of protective secondary metabolites.
Hongtao Zhang +7 more
semanticscholar +1 more source