Results 1 to 10 of about 483,373 (407)

Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020)

open access: yesChemical Reviews, 2023
The tetrahydroisoquinoline (THIQ) natural products constitute one of the largest families of alkaloids and exhibit a wide range of structural diversity and biological activity.
Alexia N Kim, Brian M Stoltz
exaly   +2 more sources

Biosynthesis of medicinal tropane alkaloids in yeast

open access: yesNature, 2020
Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for treating neuromuscular disorders and are classified as essential medicines by the World Health Organization 1 , 2 .
Prashanth Srinivasan, Christina D Smolke
exaly   +2 more sources

Biologically active quinoline and quinazoline alkaloids part I

open access: yesMedicinal Research Reviews, 2018
Susan L Morris-Natschke   +2 more
exaly   +2 more sources

Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

open access: yesCancer Cell International, 2022
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy, along with others, which not only put a tremendous economic effect on ...
P. Dhyani   +11 more
semanticscholar   +1 more source

Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

open access: yesFrontiers in Pharmacology, 2022
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from plants. In this review, the advances in bioactive alkaloids with respect to their chemical structures, herbal sources, and effects for the prevention and treatment ...
Bingfeng Lin   +6 more
doaj   +1 more source

A mass spectrometry imaging approach on spatiotemporal distribution of multiple alkaloids in Gelsemium elegans

open access: yesFrontiers in Plant Science, 2022
Gelsemium elegans contains multiple alkaloids with pharmacological effects, thus researchers focus on the identification and application of alkaloids extracted from G. elegans. Regretfully, the spatiotemporal distribution of alkaloids in G.
Zi-Han Wu   +4 more
doaj   +1 more source

Diversity in Chemical Structures and Biological Properties of Plant Alkaloids

open access: yesMolecules, 2021
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites endowed with countless biological activities. Plants are armored with these naturally produced nitrogenous compounds to combat numerous challenging environmental ...
S. Bhambhani, K. R. Kondhare, A. Giri
semanticscholar   +1 more source

Bioactive Alkaloids as Secondary Metabolites from Plant Endophytic Aspergillus Genus

open access: yesMolecules, 2023
Alkaloids represent a large family of natural products with diverse structures and bioactivities. These compounds and their derivatives have been widely used in clinics to treat various diseases.
Juntai Zhu   +5 more
doaj   +1 more source

Therapeutic Role of Alkaloids and Alkaloid Derivatives in Cancer Management

open access: yesMolecules, 2023
Cancer is a neoplastic disease that remains a global challenge with a reported prevalence that is increasing annually. Though existing drugs can be applied as single or combined therapies for managing this pathology, their concomitant adverse effects in ...
K. Olofinsan, H. Abrahamse, B. George
semanticscholar   +1 more source

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