Results 51 to 60 of about 144,211 (333)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

KOtBu as a Single Electron Donor? Revisiting the Halogenation of Alkanes with CBr4 and CCl4

Molecules, 2018
The search for reactions where KOtBu and other tert-alkoxides might behave as single electron donors led us to explore their reactions with tetrahalomethanes, CX4, in the presence of adamantane.
Katie J. Emery, Allan Young, J. Norman Arokianathar, Tell Tuttle, John A. Murphy   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

alkanes

, 2014
Citation: 'alkanes' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.A00222 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +2 more sources

Change of refractive indices in ternary mixtures containing chlorobenzene + n-hexane + (n-heptane or n-octane) at 298.15 K [PDF]

Journal of the Serbian Chemical Society, 2004
The refractive indices of ternary mixtures of chlorobenzene + n-hexane (n-heptane or n-octane) have been measured at 298.15 K and at atmospheric pressure over the whole composition diagram.
Touriño A., Hervello M., Moreno V., Marino G., Iglesias M.   +4 more
doaj   +1 more source

Estimation of the solubility parameters of model plant surfaces and agrochemicals: a valuable tool for understanding plant surface interactions [PDF]

, 2012
Background Most aerial plant parts are covered with a hydrophobic lipid-rich cuticle, which is the interface between the plant organs and the surrounding environment.
AL Samuels, B Aryal, B Bhushan, BA Uhlig, BC Hancock, C Neinhuis, C Neinhuis, CE Jeffree, CH Jeffree, CM Hansen, DJ Greenhalgh, DK Kosma, DW van Krevelen, DW van Krevelen, E Domínguez, EJ Johnson, EP Parsons, F Kardel, G Kerstiens, H L, H Schott, HJ Ensikat, J Burkhardt, J Graça, JA Heredia-Guerrero, JF Villena, K Koch, L Rapley, M Dias, M Javelle, M Khayet, M Khayet, M Khayet, M Kissinger, M Nosonovsky, M Pollard, M Riederer, M Riederer, MA O’Neill, MG Wirthensohn, MG Wirthensohn, MJ Steinbauer, Mohamed Khayet, MT Tyree, MW Samaha, P Wagner, PE Kolattukudy, PE Kolattukudy, PE Kolattukudy, PJ Holloway, R Gröning, RA Burton, S Bauer, S Pandey, T Eichert, T Scherbatskoy, TH Jones, TH Yeats, V Fernández, V Fernández, Victoria Fernández, VY Senichev   +61 more
core   +8 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Cagelike Octacopper Methylsilsesquioxanes: Self-Assembly in the Focus of Alkaline Metal Ion Influence—Synthesis, Structure, and Catalytic Activity

Molecules, 2023
A family of unusual octacopper cage methylsilsesquioxanes 1–4 were prepared and characterized. Features of their cagelike (prismatic) structure were established using X-ray diffraction studies.
Alexey N. Bilyachenko, Ivan S. Arteev, Victor N. Khrustalev, Anna Y. Zueva, Lidia S. Shul’pina, Elena S. Shubina, Nikolay S. Ikonnikov, Georgiy B. Shul’pin   +7 more
doaj   +1 more source

Trace-gas metabolic versatility of the facultative methanotroph Methylocella silvestris [PDF]

, 2014
The climate-active gas methane is generated both by biological processes and by thermogenic decomposition of fossil organic material, which forms methane and short-chain alkanes, principally ethane, propane and butane1, 2. In addition to natural sources,
A Crombie, AR Theisen, B Gilbert, C Anthony, CJ Marx, CM Reddy, D Mackay, EL Johnson, FD Mango, G Etiope, G Etiope, G Etiope, G Etiope, H Barrios, IR McDonald, J Colby, J Heider, J Sambrook, JD Semrau, JG Leahy, K Tamura, KU Hinrichs, MJ Green, MT Rahman, N Hamamura, NA Patel, NV Coleman, NV Coleman, OU Mason, P Guerlava, RB Cooley, SD Prior, SG Osborn, SN Dedysh, T Furuya, T Kotani, T Kotani, VJ Patel, W Ashraf, WS Reeburgh, Y Chen   +40 more
core   +1 more source