Results 121 to 130 of about 2,197 (160)

Design and synthesis of prostate cancer antigen-1(PCA-1/ALKBH3)inhibitors as anti-prostate cancer drugs

Design and synthesis of prostate cancer antigen-1(PCA-1/ALKBH3)inhibitors as anti-prostate cancer drugs
2016年度
openaire  

ADAMDEC1-driven CCL2-CCR2-PD-1 axis in esophageal squamous cell carcinoma: a dual threat of O-GlcNAcylation and m⁶A methylation in neoadjuvant therapy resistance and immune evasion. [PDF]

Cell Oncol (Dordr)
Cheng J, Ma H, Qian X, Xing W.
europepmc   +1 more source

TRMT6-directed m¹A modification initiates lung squamous cell carcinoma via YTHDF3-stabilized cell cycle genes. [PDF]

NPJ Precis Oncol
Xue W, Zhu L, Wei X, Sun J, Lin W, Huang S, Wu L, Zhang D.   +7 more
europepmc   +1 more source

m⁶A demethylase-driven reprogramming of leukemia-associated macrophages predicts improved outcomes in acute myeloid leukemia. [PDF]

Front Immunol
Shi Z, Xia Y, Zhang M, Peng Y, An Y, Zhu Q, Sun T.   +6 more
europepmc   +1 more source

In vitro selection of N ¹-methyladenosine-sensitive RNA-cleaving deoxyribozymes with 10⁵-fold selectivity over unmethylated RNA. [PDF]

Chem Sci
Shi J, Zhang Q, Wu Y, Chang Y, Liu M.
europepmc   +1 more source

QM/MM simulations of the rate limiting step in the dealkylation reaction catalyzed by ALKBH2 and ALKBH3

, 2020
Alice R. Walker, Gerardo A Cisneros, Erik Antonio Vazquez Montelongo   +2 more
openaire   +1 more source

Harnessing m1A modification: a new frontier in cancer immunotherapy. [PDF]

Front Immunol
Wang X, Ma X, Chen S, Fan M, Jin C, Chen Y, Wang S, Wang Z, Meng F, Zhang C, Yang L.   +10 more
europepmc   +1 more source

Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB. [PDF]

Nucleic Acids Res
Kaur S, Maheswaran P, Kaur S, Lai Y, Salah E, Zhang D, Shishodia S, Schofield CJ, Aik WS.   +8 more
europepmc   +1 more source

DNA repair helicases: from mechanistic understanding to therapeutic implications. [PDF]

NAR Cancer
Menon V, Gueble SE.
europepmc   +1 more source

Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation. [PDF]

J Biol Chem
Gutierrez R, Chan AYS, Lai SWT, Itoh S, Lee DH, Sun K, Battad A, Chen S, O'Connor TR, Shuck SC.   +9 more
europepmc   +1 more source