Results 241 to 250 of about 504,742 (339)

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Palladium-Catalyzed Deaminative Cross-Coupling of Alkyl Nitroso Carbamates. [PDF]

ACS Catal
Paul S, Kumawat KR, Brown MK.
europepmc   +1 more source

Evaluation of Alkyl‐Ferrocene Monolayers on Carbons for Charge Storage Applications, a Voltammetry and Impedance Spectroscopy Investigation

, 2019
Yara Aceta, Yann R. Leroux, Philippe Hapiot   +2 more
openalex   +2 more sources

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

A Unified Synthetic Approach to 2-Alkyl Azetidines, Oxetanes, Thietanes and Cyclobutanes from Unactivated Alkenes. [PDF]

J Am Chem Soc
Buck L, Pelosi M, Paul S, Wheatley E, Richardson A, Ghosh S, Sardelli F, Silvi M.   +7 more
europepmc   +1 more source

Hysteretic thermal spin-crossover in heteroleptic Fe( ii ) complexes using alkyl chain substituted 2,2′-dipyridylamine ligands

, 2019
Blaise L. Geoghegan, Wasinee Phonsri, Peter N. Horton, James B. Orton, Simon J. Coles, Keith S. Murray, Peter J. Cragg, Marcus K. Dymond, Ian A. Gass   +8 more
openalex   +2 more sources

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Biomimetic sulfur-catalyzed carbonyl transfer enables the carbonylative difunctionalization of unactivated alkenes. [PDF]

Chem Sci
Wang Y, Wu XF.
europepmc   +1 more source

Alkyl chain length influence of the functionalized diethanolamine ligand on the slow relaxation of the magnetization in {CoIII3DyIII3} complexes

Chloë Bonnenfant, Nahir Vadra, Mathieu Rouzières, Rodolphe Clérac, Fabio D. Cukiernik, Pablo Alborés   +5 more
openalex   +2 more sources

All‐Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters

Advanced Science, EarlyView.
A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker, Koki Takeuchi, Carolin Süßmuth, Frederico Boekhoff, Martin A. Schäfer, Shunsuke Kato, Alexander Hoffmann, Takashi Hayashi, Sonja Herres‐Pawlis   +8 more
wiley   +1 more source