Results 241 to 250 of about 480,912 (334)

Mg(SPh)2 as a Catalyst for Efficient Photocatalytic Alkylation Reactions of Active Methylene Compounds with Nonactivated Alkenes

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 5, March 4, 2025.
Abstract Mg(SPh)2 has been found to be a highly active catalyst in photocatalytic alkylation reactions of active methylene compounds with nonactivated alkenes. The desired reactions proceeded smoothly to afford the corresponding alkylated products in high yields with low catalyst loadings (0.2–0.3 mol%). This protocol is applicable to a continuous‐flow
Yasuhiro Yamashita   +3 more
wiley   +1 more source

Asymmetric Synthesis of Highly Substituted Spiro[2H‐pyrrole‐2,3‐Succinimide] Derivatives by Copper‐Catalyzed Post‐Ugi Reactions

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract Herein we present a novel one‐pot methodology for the synthesis of enantioenriched 2H‐pyrrolespirosuccinimides by copper‐catalyzed reactions on Ugi adducts derived from enantiopure α‐alkylbenzyl amines through a chirality transfer process. We have proposed a mechanism, supported by density functional theory (DFT) calculations, where a hydrogen
Javier Gómez‐Ayuso   +3 more
wiley   +1 more source

Rapid Oxygen Atom Transfer at a Catalysis-Relevant Ni(I)-Alkyl Complex with N<sub>2</sub>O. [PDF]

open access: yesJ Am Chem Soc
Mateos-Calbet A   +5 more
europepmc   +1 more source

Synthesis of Spirolactones from Carbonyls via Carboborylation of N‐Sulfonylhydrazones with Alkoxycarbonylalkylboronic Acids

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Spirolactones are readily prepared from carbonyls via their N‐tosylhydrazones. The reaction involves carboborylation with ethoxycarbonyl‐substituted boronic acids, followed by oxidation and lactonization. Thermal or photochemical protocols enable versatility.
Lucía López   +3 more
wiley   +1 more source

In-silico analysis of potential phytochemicals targeting mitogen activating protein kinase-14 (MAPK14) gene in colorectal cancer. [PDF]

open access: yesSci Rep
Khalid M   +14 more
europepmc   +1 more source

Photochemical Preparation of (Aza−)Indolines: Diastereoselective Synthesis and Polarity Reversal Strategy

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract Herein, we present the first light‐mediated, diastereoselective de novo synthesis for 2,3‐substituted indolines, a privileged scaffold in pharmaceuticals. The protocol was tested with various aryl and alkyl groups, maintaining high yields up to 85% across different substituents.
Julian J. Melder   +7 more
wiley   +1 more source

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