Results 1 to 10 of about 3,618 (129)

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases. [PDF]

Angew Chem Int Ed Engl
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Damian M, Tseliou V, Peters P, Knaus T, Mutti FG.   +4 more
europepmc   +3 more sources

Catalytic Strategies for Stereoselective Carbohydrate Synthesis: Emerging Concepts for Accessing Challenging Glycosides. [PDF]

Angew Chem Int Ed Engl
The recent developments in catalytic stereoselective carbohydrate synthesis are presented. The converging synthetic trajectories of the catalytic and carbohydrate communities are discussed, including impactful case studies exemplifying noncovalent catalysis, radical catalysis, asymmetric catalysis and new catalytic modalities.
Loh CCJ.
europepmc   +3 more sources

Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective. [PDF]

J Med Chem
Bhattarai P, Trombley TA, Altman RA.
europepmc   +1 more source

Biocatalytic Synthesis of α-Amino Esters via Nitrene C-H Insertion. [PDF]

J Am Chem Soc
Alfonzo E, Hanley D, Li ZQ, Sicinski KM, Gao S, Arnold FH.   +5 more
europepmc   +1 more source

Stereospecific Enzymatic Conversion of Boronic Acids to Amines. [PDF]

J Am Chem Soc
Hanley D, Li ZQ, Gao S, Virgil SC, Arnold FH, Alfonzo E.   +5 more
europepmc   +1 more source

Engineering protein prenylation: an emerging tool for selective protein modification. [PDF]

Biochem Soc Trans
Venkatachalapathy S, Lichtenfels C, Wagner CR, Distefano MD.   +3 more
europepmc   +1 more source

MARTS-DB: a database of mechanisms and reactions of terpene synthases. [PDF]

BMC Bioinformatics
Engst M, Brokeš M, Čalounová T, Samusevich R, Bushuiev R, Bushuiev A, Chatpatanasiri R, Tajovská A, Akmeşe SM, Perković M, Soldát M, Sivic J, Pluskal T.   +12 more
europepmc   +1 more source

Integrated network toxicology, molecular docking, and molecular dynamics simulation reveals mechanisms of benzo[a]pyrene-induced pan-cancer. [PDF]

BMC Pharmacol Toxicol
Pan Y, Qin S, Chen C, He S, Zhang M, Hou J, Wang J, Wang Z, Zhao M.   +8 more
europepmc   +1 more source

Bimolecular Homolytic Substitution (S_H2) and Radical Ligand Transfer (RLT): Emerging Paradigms in Radical Transformations. [PDF]

ACS Cent Sci
Fernandes AJ, Katayev D.
europepmc   +1 more source

Vinigrol Tricyclic Scaffold Biosynthesis Employs an Atypical Terpene Cyclase and a Multipotent Cyclization Cascade. [PDF]

J Am Chem Soc
Tsukada K, Sato F, Matsuyama T, Matsuda R, Ozaki T, Morishita Y, Furumura S, Homma Y, Sekiya H, Sugawara A, Kubota M, Mitsuhashi T, Yasuno Y, Shinada T, Nagata R, Kuzuyama T, Taniguchi T, Fujita M, Uchiyama M, Asai T.   +19 more
europepmc   +1 more source