Results 131 to 140 of about 80,529 (226)

Non-alkylating agents-induced gonadotoxicity in pre-pubertal males: Insights on the clinical and pre-clinical front. [PDF]

Clin Transl Sci
Sriram S, Macedo T, Mavinkurve-Groothuis A, van de Wetering M, Looijenga LHJ.   +4 more
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Abrogation of the G2/M checkpoint as a chemosensitization approach for alkylating agents. [PDF]

Neuro Oncol
Lang F, Cornwell JA, Kaur K, Elmogazy O, Zhang W, Zhang M, Song H, Sun Z, Wu X, Aladjem MI, Aregger M, Cappell SD, Yang C.   +12 more
europepmc   +1 more source

A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents. [PDF]

Cancer Res, 2020
Sapkota Y, Wilson CL, Zaidi AK, Moon W, Fon Tacer K, Lu L, Liu Q, Baedke J, Dhaduk R, Wang Z, Chemaitilly W, Krasin MJ, Berry FB, Zhang J, Hudson MM, Robison LL, Green DM, Yasui Y.   +17 more
europepmc   +1 more source

Enzyme activated alkylating agents [PDF]

British Journal of Cancer, 1973
C R, Ball, J A, Double, J, Goodban
openaire   +2 more sources

Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging

VIEW, EarlyView.
Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao, Jingyu Deng, Qin Li, Tong Xia, Xun Yang, Simei Yang, Changzhen Sun, Xia Xiong, Li Liu   +8 more
wiley   +1 more source

Development of Syngeneic Murine Glioma Models with Somatic Mismatch Repair Deficiency to Study Therapeutic Responses to Alkylating Agents and Immunotherapy. [PDF]

Curr Protoc
Bhatt D, Sundaram RK, López KSL, Lee T, Gueble SE, Vasquez JC.   +5 more
europepmc   +1 more source

The Multifaceted Role of Rad9 in the DNA Damage Response of Saccharomyces cerevisiae

Yeast, EarlyView.
ABSTRACT To maintain the integrity of the genome, cells have evolved a complex signalling system, termed the DNA damage response (DDR), which detects DNA damage and promotes DNA repair. To date, over 600 proteins have been identified that play an integral role in the DDR. RAD9, encoding a DDR mediator protein, was the prototypical DNA damage checkpoint
A. Kiely, F. O'Halloran, P. Young, N. F. Lowndes, M. Grenon, K. Finn   +5 more
wiley   +1 more source

Combination Therapy with Immune Checkpoint Inhibitors and Histone Deacetylase Inhibitors or Alkylating Agents. [PDF]

Cancer Manag Res
Joerger M, Koster KL, Janik T, de Jong FA.   +3 more
europepmc   +1 more source

Development and evaluation of pupal color‐based genetic sexing strains in Anastrepha obliqua (Diptera: Tephritidae)

Insect Science, EarlyView.
Two spontaneous mutations in pupae of the West Indian fruit fly Anastrepha obliqua, named bp and sp, were isolated and studied. The bp mutation was selected, and using two types of Y‐autosoma l translocation inducers and an appropriate crossing scheme, two genetically sexed strains based on pupa l color were developed for the first time in this species,
Daisy P. Cárdenas‐Enríquez, Víctor García‐Martínez, Jorge Ibáñez‐Palacios, Brenda Torres‐Huerta, Maria F. Ruiz‐Pérez, José S. Meza   +5 more
wiley   +1 more source