Results 191 to 200 of about 80,529 (226)

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +1 more source

Photoinduced Generation of (Boryl)Silyl and (Chloro)Silyl Radicals: Access to Trisubstituted Silylboranes and Chlorosilanes

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A versatile photoinduced hydro(boryl)silylation and hydro(chloro)silylation of alkenes to construct trisubstituted silylboranes and chlorosilanes was achieved through in situ generation of (boryl)silyl radicals or (chloro)silyl radicals. This mild methodology affords high chemoselectivity and broad functional group tolerance to enable direct access to ...
Mone Suzuki, Yuki Nagashima
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

[Alkylating agents].

Bulletin du cancer, 2011
With the approval of mechlorethamine by the FDA in 1949 for the treatment of hematologic malignancies, alkylating agents are the oldest class of anticancer agents. Even though their clinical use is far beyond the use of new targeted therapies, they still occupy a major place in specific indications and sometimes represent the unique option for the ...
Victor A. Filadora, Mark J. Lema
  +5 more sources

Alkylating agent resistance

1989
The phenotypic expression of intrinsic or natural resistance and the selection of acquired resistance through sublethal exposure to anticancer agents remain major obstacles to the successful treatment of human neoplasms. A large number of solid tumors that fail to respond to chemotherapy do so because they possess characteristics that allow them to ...
M L, Clapper, K D, Tew
openaire   +2 more sources

Alkylating Agents in Bronchogenic Carcinoma

Journal of Occupational and Environmental Medicine, 1969
Abstract A large number of patients in a group of Veterans Administration Hospitals received a variety of alkylating agents in studies in which these agents were randomized with an inert compound. Intravenous cyclophosphamide, and possibly nitrogen mustard, had a slight favorable influence upon survival for all patients.
R A, Green, E, Humphrey, H, Close, M E, Patno   +3 more
openaire   +2 more sources

Alkylating Agents

Dermatologic Therapy, 2002
Juris Germanas, Amit G. Pandya
openaire   +2 more sources

ALKYLATING AGENTS

British Medical Bulletin, 1964
P, BROOKES, P D, LAWLEY
openaire   +2 more sources