Results 191 to 200 of about 3,196,403 (286)

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Regulation And Expression Of The Adaptive Response To Alkylating Agents

, 1988
T Lindahl
openalex   +1 more source

Versatile Direct (Hetero)Arylation Polymerization of Electro‐Deficient Unsubstituted Thiazolo[5,4‐d]Thiazole: A Tool to Lower the LUMO Level

Macromolecular Rapid Communications, EarlyView.
An unsubstituted thiazolo[5,4‐d]thiazole (TzTz) unit is used to synthesize a series of novel semiconducting polymers via eco‐friendly direct arylation polymerization. These TzTz‐based copolymers, with various electron‐withdrawing comonomers, display optical bandgaps of 1.5–2.0 eV and strong thermal stability.
Badr Jismy, Pablo Durand, Jasmine P. Jacob, Fanny Richard, Olivier Boyron, Benoit Heinrich, Bruno Schmaltz, Patrick Lévêque, Olivier Bardagot, Nicolas Leclerc   +9 more
wiley   +1 more source

Sensitization to Radiation and Alkylating Agents by Inhibitors of Poly(ADP-ribose) Polymerase Is Enhanced in Cells Deficient in DNA Double-Strand Break Repair

Molecular Cancer Therapeutics, 2010
Dana A. Löser, A. Shibata, A. Shibata, L. Woodbine, P. Jeggo, A. Chalmers   +5 more
semanticscholar   +1 more source

Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy

Medicinal Research Reviews, EarlyView.
ABSTRACT Cerebral tumors, particularly in pediatric patients, pose a significant challenge in oncology. Radiotherapy is a crucial component of the multimodal treatment approach for these tumors. Understanding the molecular basis of these tumors, particularly their response to radiotherapy, is crucial for improving treatment outcomes and patient ...
Ahana Maitra, Morena Miciaccia, Manuela Mandorino, Domenico Armenise, Olga Maria Baldelli, Savina Ferorelli, Ludmila Papusha, Alexander Druy, Maria Grazia Perrone, Antonio Scilimati   +9 more
wiley   +1 more source

In‐Silico Exploration of the StreptomeDB Database for Potential Irreversible DprE1 Inhibitors toward Antitubercular Treatment

ChemistryOpen, EarlyView.
StreptomeDB‐derived nitro compounds are screened against Mycobacterium tuberculosis decaprenylphosphoryl‐D‐riboseoxidase (DprE1) . Covalent docking, molecular dynamics simulations, and molecularmechanics/generalized Born surface area analyses identify hydroxythaxtomin and lajollamycin B as potent DprE1 inhibitors, surpassing the reference PBTZ169 in ...
Doaa G. M. Mahmoud, Gamal A. H. Mekhemer, Mohamed‐Elamir F. Hegazy, Jabir H. Al‐Fahemi, Mahmoud A. A. Ibrahim   +4 more
wiley   +1 more source

Separation of the SOS-dependent and SOS-independent components of alkylating-agent mutagenesis

, 1989
Linda B. Couto, Ishrat Chaudhuri, Brian A. Donahue, Bruce Demple, John M. Essigmann   +4 more
openalex   +1 more source

Reproductive adverse events in patients with non‐Hodgkin lymphoma treated with chemotherapeutic regimens including cyclophosphamide, doxorubicin, vincristine, prednisone or CHOP with rituximab: A systematic review and meta‐analysis

Pediatric Discovery, EarlyView.
The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R‐CHOP) is the first‐line treatment for non‐Hodgkin lymphoma (NHL). Nine articles involving 331 patients were included in the meta‐analysis, the pooled proportion of reproductive adverse events was 22.3% (95% CI 11.4%–33.2%; p < 0.001). The findings
Rong Han, Jie Zhao, Chengjun Yu, Ling Wang, Long Chen, Yang Hu, Shengde Wu   +6 more
wiley   +1 more source

Increased therapeutic efficiency of a lipid-soluble alkylating agent incorporated in liposomes

, 1982
J Babbage, M. C. Berenbaum
openalex   +2 more sources

Determination of Reductant and Alkylating Agent in the Alkylated Human Immunoglobulin by High Performance Liquid Chromatography

, 1982
Hideyuki Morita, Tetsuya Konishi
openalex   +2 more sources