Results 201 to 210 of about 81,731 (287)

Chemotherapy‐induced alopecia: an exploratory questionnaire‐based study from Israel comparing knowledge, attitudes, and management practices among dermatologists and oncologists

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives: Chemotherapy‐induced alopecia, encompassing both acute reversible alopecia and its persistent form, significantly impacts patients' quality of life but remains inadequately addressed. This study aimed to compare dermatologists' and oncologists' knowledge, attitudes, and practices regarding chemotherapy‐induced ...
Anna Lyakhovitsky, Oz Segal, Ester Vizan, Arad Dotan, Riad Kassem, Keren Lyakhovitsky, Avner Shemer, Baruch Kaplan, Eran Galili, Aviv Barzilai   +9 more
wiley   +1 more source

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents. [PDF]

Cancer Discov, 2019
Lossos C, Liu Y, Kolb KE, Christie AL, Van Scoyk A, Prakadan SM, Shigemori K, Stevenson KE, Morrow S, Plana OD, Fraser C, Jones KL, Liu H, Pallasch CP, Modiste R, Nguyen QD, Craig JW, Morgan EA, Vega F, Aster JC, Sarosiek KA, Shalek AK, Hemann MT, Weinstock DM.   +23 more
europepmc   +1 more source

Coordinating Fertility Preservation in Children and Young Adults at Risk of Treatment‐Induced Infertility: A Commentary

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Ursula Blyth, Pedro Melo, Rod T. Mitchell, Suzannah A. Williams, Ephia Yasmin, Phillipa Sangster, Kokila Lakhoo, Sheila Lane, Richard A. Anderson, Christian M. Becker   +9 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide. [PDF]

Mutat Res Genet Toxicol Environ Mutagen, 2019
Muenter MM, Aiken A, Akanji JO, Baig S, Bellou S, Carlson A, Conway C, Cowell CM, DeLateur NA, Hester A, Joshi C, Kramer C, Leifer BS, Nash E, Qi MH, Travers M, Wong KC, Hu M, Gou N, Giese RW, Gu AZ, Beuning PJ.   +21 more
europepmc   +1 more source

Redox environment modulates aggregation of ataxin‐3 in vitro — Implications for drug screening of cysteine‐rich proteins

The FEBS Journal, EarlyView.
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak, Martina Sollazzo, Elisa Monaca, Raffaele Sabbatella, Maria Agnese Morando, Oleg Chertkov, Laura Puglisi, Martina Mascellino, Anna Fricano, Sandra Macedo‐Ribeiro, Caterina Alfano   +10 more
wiley   +1 more source

GCN2 in proteostasis: structural logic, signalling networks and disease

The FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

First Report of Brazilian Free-tailed Bat Maternity Colonies in Arkansas [PDF]

, 1983
Beggs, Teresa E., Efaw, Clark, Heath, Darrell R., Heidt, Gary A., Saugey, David A.   +4 more
core   +2 more sources

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Measurement of the DNA alkylating agents busulfan and melphalan in human plasma by mass spectrometry. [PDF]

J Chromatogr B Analyt Technol Biomed Life Sci, 2019
Schofield RC, Landau HJ, Giralt SA, Shah GL, Scordo M, Lin A, Zanutto E, Ramanathan LV, Pessin MS, Carlow DC.   +9 more
europepmc   +1 more source