Results 221 to 230 of about 51,251 (261)
Plant Breeding, EarlyView.ABSTRACT Historically cultivated for medicinal and dyeing purposes, safflower (Carthamus tinctorius L.) saw a shift towards widespread oilseed production after the 1920s due to the growing importance of oils. However, there is a renewed interest in its medicinal and dyeing properties today.
Tansu Uskutoglu +2 more
wiley +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Plant growth–promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium distachyon under contrasting nitrogen (N) regimes using time‐resolved phenotyping, elemental analysis ...
Stefan Sanow +12 more
wiley +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
Photochemistry and Photobiology, EarlyView.UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source
Bulletin du cancer, 2011 With the approval of mechlorethamine by the FDA in 1949 for the treatment of hematologic malignancies, alkylating agents are the oldest class of anticancer agents. Even though their clinical use is far beyond the use of new targeted therapies, they still occupy a major place in specific indications and sometimes represent the unique option for the ...
Victor A. Filadora, Mark J. Lema
core +5 more sources
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Alkylating Agents in Bronchogenic Carcinoma
Journal of Occupational and Environmental Medicine, 1969Abstract A large number of patients in a group of Veterans Administration Hospitals received a variety of alkylating agents in studies in which these agents were randomized with an inert compound. Intravenous cyclophosphamide, and possibly nitrogen mustard, had a slight favorable influence upon survival for all patients.
R A, Green +3 more
openaire +2 more sources
1989
The phenotypic expression of intrinsic or natural resistance and the selection of acquired resistance through sublethal exposure to anticancer agents remain major obstacles to the successful treatment of human neoplasms. A large number of solid tumors that fail to respond to chemotherapy do so because they possess characteristics that allow them to ...
M L, Clapper, K D, Tew
openaire +2 more sources
The phenotypic expression of intrinsic or natural resistance and the selection of acquired resistance through sublethal exposure to anticancer agents remain major obstacles to the successful treatment of human neoplasms. A large number of solid tumors that fail to respond to chemotherapy do so because they possess characteristics that allow them to ...
M L, Clapper, K D, Tew
openaire +2 more sources
On the Biological Alkylating Agents
Perspectives in Biology and Medicine, 1973Les poisons peuvent etre employes comme agents de destruction de la vie ou comme moyens de guerison des maladies; mais, outre ces deux usages bien connus de tout le monde, il en est un troisieme qui interesse particulierement le physiologiste. Pour lui, le poison devient un instrument qui dissocie et analyse les phenomenes les plus delicats de la ...
openaire +2 more sources